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PCA inhibits multiple pathways involved in development of diabetic nephropathy

Diabetic nephropathy is one of the most serious complications related to diabetes, often leading to end-stage kidney disease. Purple corn grown in Peru and Chile is a relative of blue corn, which is readily available in the U.S.

20 Sep 2012

New 3D endoscope at UMDNJ-The University Hospital can treat complex neurosurgical diseases

Ana Cores, a 54-year old Hackensack resident, worried about how a sudden loss of peripheral vision would impact the quality of her life. After undergoing MRIs, eye exams and many diagnostic tests, Cores opted to visit UMDNJ-The University Hospital where Dr. James K. Liu, a skull base neurosurgeon, and Dr. Jean Anderson Eloy, an otolaryngologist, used a new three- dimensional endoscope to remove a brain tumor through her nose that was pressing on her optic nerve and causing her to go blind.

20 Sep 2012

RRM2 may be a facilitating factor in colorectal cancer and UV-induced DNA damage repair

Colorectal cancer (CRC) is the leading cause of cancer-related death worldwide. In addition, the incidence and mortality rates of colorectal cancer are on the rise. Recently, metabolic genes have received increasing and specific attention due to their potential role in carcinogenesis.

20 Sep 2012

Hip implants are more likely to fail in obese people due to thigh size

University of Iowa researchers have determined that thigh size in obese people is a reason their hip implants are more likely to fail.

20 Sep 2012

Therapeutic video games can show health-related benefits

Can video games help patients with cancer, diabetes, asthma, depression, autism and Parkinson's disease? A new publication by researchers from the University of Utah, appearing in the Sept 19 issue of the journal Science Translational Medicine, indicates video games can be therapeutic and are already beginning to show health-related benefits.

20 Sep 2012

FDA Oncologic Drugs Advisory Committee to review Celgene’s pomalidomide NDA on Nov. 8

Celgene Corporation today announced the U.S. Food and Drug Administration's (FDA) Oncologic Drugs Advisory Committee will hold a review of the Company's new drug application (NDA) for pomalidomide at its meeting on November 8, 2012.

20 Sep 2012

Endothelial colony-forming cells show promise against inflammatory bowel disease

New research shows that a special population of stem cells found in cord blood has the innate ability to migrate to the intestine and contribute to the cell population there, suggesting the cells' potential to treat inflammatory bowel disease (IBD).

20 Sep 2012

Greater adherence to DASH diet can lead to significant reductions in blood pressure

The Dietary Approaches to Stop Hypertension (DASH) diet, which promotes consumption of more fruits, vegetables, low-fat dairy products, and whole grain, and less meats and sweets, is a proven effective treatment for hypertension. For some individuals, adherence to the diet can be just as effective in lowering blood pressure as taking antihypertensive medication.

20 Sep 2012

New 24/7 Cardiologist program now available at ProMedica Toledo Hospital

ProMedica Toledo Hospital is the only hospital in northwest Ohio with a cardiologist on duty 24 hours a day, seven days a week, to treat patients who may be experiencing a heart attack.

20 Sep 2012

British Medical Association commends two textbooks by Loyola neurologist

Two textbooks co-authored by Loyola University Medical Center neurologist Dr. Jos- Biller have been named "Highly Commended" in the 2012 British Medical Association Medical Book Awards.

20 Sep 2012

Aerpio Therapeutics commences AKB-9778 Phase 1b/2a trial in diabetic macular edema

Aerpio Therapeutics, a clinical-stage biopharmaceutical company developing innovative therapies for vascular diseases by targeting the Tie2 pathway, today announced that it has dosed the first patient in a Phase 1b/2a trial of AKB-9778 for the treatment of diabetic macular edema (DME).

20 Sep 2012

Enrollment complete in Gamida Cell’s NiCord Phase I/II trial for hematological malignancies

Gamida Cell, a leader in adult stem cell expansion technologies and products, announced today that it has completed enrollment for a Phase I/II clinical trial of NiCord, the company's second pipeline product.

20 Sep 2012

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

Obese adults with excess visceral fat (fat located inside the abdominal cavity, around the body's internal organs) and biomarkers of insulin resistance had an associated increased risk for the development of type 2 diabetes mellitus, while obese individuals with higher amounts of total body fat and subcutaneous fat (underneath the skin) did not have this increased risk, according to a study in the September 19 issue of JAMA, and theme issue on obesity.

20 Sep 2012

Tasered adolescents do not appear to be at increased risk for serious injury

Adolescents who are tasered by law enforcement officers do not appear to be at higher risk for serious injury than adults, according to new a new study from Wake Forest Baptist Medical Center researchers.

20 Sep 2012

Small subset of patients with OAG accounts for large proportion of all glaucoma-related charges

A small subset of patients with open-angle glaucoma (OAG) account for a large proportion of all glaucoma-related charges in the United States, according to new data published by researchers at the University of Michigan Kellogg Eye Center and Washington University, St. Louis.

20 Sep 2012

Complete story behind connection between XMRV virus and prostate cancer

A once-promising discovery linking prostate cancer to an obscure retrovirus derived from mice was the result of an inadvertent laboratory contamination, a forensic analysis of tissue samples and lab experiments - some dating back nearly a decade - has confirmed.

20 Sep 2012

APR-246 can restore function of defective p53 and activate apoptosis in cancer cells

The p53 gene plays a key role in the prevention of cancer, by blocking cell growth and triggering programmed cell death or apoptosis. If, however, p53 has mutated and become defective, the cancer cells can acquire the ability to evade apoptosis and become more resistant to therapy.

20 Sep 2012

Study examines association of Roux-en-Y gastric bypass surgery with weight loss, diabetes mellitus

Severely obese patients who had Roux-en-Y gastric bypass surgery had significant weight loss that was sustained for an average of 6 years after the surgery and also experienced frequent remission and lower incidence of diabetes, hypertension, and abnormal cholesterol levels, compared to participants who did not have the surgery, according to a study in the September 19 issue of JAMA, and theme issue on obesity.

20 Sep 2012

Loyola study to evaluate whether transcranial magnetic stimulation can help people with tinnitus

Loyola University Medical Center is studying whether a new form of non-invasive magnetic therapy can help people who suffer debilitating tinnitus (ringing in the ears).

19 Sep 2012

Children and adolescents with high BPA levels more likely to have obesity

In a nationally representative sample of nearly 3,000 children and adolescents, those who had higher concentrations of urinary bisphenol A (BPA), a manufactured chemical found in consumer products, had significantly increased odds of being obese, according to a study in the September 19 issue of JAMA, and theme issue on obesity.

19 Sep 2012

Medical Condition News

PCA inhibits multiple pathways involved in development of diabetic nephropathy

New 3D endoscope at UMDNJ-The University Hospital can treat complex neurosurgical diseases

RRM2 may be a facilitating factor in colorectal cancer and UV-induced DNA damage repair

Hip implants are more likely to fail in obese people due to thigh size

Therapeutic video games can show health-related benefits

FDA Oncologic Drugs Advisory Committee to review Celgene’s pomalidomide NDA on Nov. 8

Endothelial colony-forming cells show promise against inflammatory bowel disease

Greater adherence to DASH diet can lead to significant reductions in blood pressure

New 24/7 Cardiologist program now available at ProMedica Toledo Hospital

British Medical Association commends two textbooks by Loyola neurologist

Aerpio Therapeutics commences AKB-9778 Phase 1b/2a trial in diabetic macular edema

Enrollment complete in Gamida Cell’s NiCord Phase I/II trial for hematological malignancies

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

Tasered adolescents do not appear to be at increased risk for serious injury

Small subset of patients with OAG accounts for large proportion of all glaucoma-related charges

Complete story behind connection between XMRV virus and prostate cancer

APR-246 can restore function of defective p53 and activate apoptosis in cancer cells

Study examines association of Roux-en-Y gastric bypass surgery with weight loss, diabetes mellitus

Loyola study to evaluate whether transcranial magnetic stimulation can help people with tinnitus

Children and adolescents with high BPA levels more likely to have obesity

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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