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Top-line results from Genzyme's teriflunomide and Rebif Phase III comparison trial on RMS

Genzyme, a Sanofi company, today reported top-line results from TENERE, a Phase III clinical trial comparing the effectiveness, safety and tolerability of once-daily oral teriflunomide to interferon beta-1a, an approved injectable therapy, in people with relapsing forms of multiple sclerosis.

20 Dec 2011

Top-line results from AstraZeneca and Targacept's TC-5214 Phase 3 study on MDD

AstraZeneca and Targacept, Inc. today announced top-line results from the second of four RENAISSANCE Phase 3 studies investigating the efficacy and tolerability of TC-5214 as an adjunct therapy to an antidepressant in patients with major depressive disorder (MDD) who do not respond adequately to initial antidepressant treatment.

20 Dec 2011

Lostartan can reduce cigarette smoke-induced lung injury

Chronic obstructive pulmonary disease (COPD) is among the most common causes of death in the US. It is a smoking-related disease for which there are currently no disease-altering therapies. However, hope that one could be developed is now provided by the work of Enid Neptune and colleagues, at Johns Hopkins University, Baltimore, in a mouse model of lung disease caused by exposure to cigarette smoke.

20 Dec 2011

Acupuncture can reduce protein associated with chronic stress

Acupuncture significantly reduces levels of a protein in rats linked to chronic stress, researchers at Georgetown University Medical Center (GUMC) have found. They say their animal study may help explain the sense of well-being that many people receive from this ancient Chinese therapy.

20 Dec 2011

Top winter skin care tips

As the holiday song goes, "Baby, it's cold outside." And that cold weather can wreak havoc on your skin. Wake Forest Baptist Medical Center dermatologist Amy McMichael, M.D., recommends a proactive approach to winter skin care.

20 Dec 2011

New UA cancer research centre to focus on personalised treatment options

A new cancer research centre established at the University of Adelaide will focus on treatment options tailored to the individual, taking into account DNA and genetic variations between people.

20 Dec 2011

Stabilizing mitochondria protects against Parkinson's in a rat model

Stabilizing the cell's power-generating center protects against Parkinson's disease (PD) in a rat model, according to a report published online this week in the Journal of Experimental Medicine.

20 Dec 2011

Blocking EETs may represent novel strategy for cancer therapy

Recent findings in mice suggest that blocking the production of small molecules produced in the body, known as epoxyeicosatrienoic acids (EETs), may represent a novel strategy for treating cancer by eliminating the blood vessels that feed cancer tumors.

20 Dec 2011

High blood pressure in middle age raises risk of heart attack or stroke

A hike in your blood pressure during middle age significantly raises the risk of having a heart attack or a stroke during your lifetime, according to new Northwestern Medicine research. The study offers a new understanding on the importance of maintaining low blood pressure early in middle age to prevent heart disease later in life.

20 Dec 2011

Tufts professor receives IEEE Fellow designation

Eric Miller, professor of electrical and computer engineering in the School of Engineering at Tufts University, has been elected a fellow by the Institute for Electrical and Electronics Engineers.

20 Dec 2011

EETs promote primary tumor growth and metastasis in mouse models of cancer

Drugs that enhance levels of small molecules derived naturally in the body from a major component of animal fats (small molecules known as epoxyeicosatrienoic acids [EETs]) are currently in clinical trials for the treatment of high blood pressure and diabetes.

20 Dec 2011

Impax commences IPX159 Phase IIb trial in Restless Legs Syndrome

Impax Pharmaceuticals, the branded products division of Impax Laboratories, Inc., announced that it has initiated a Phase IIb trial of its drug candidate IPX159 in patients with moderate to severe Restless Legs Syndrome.

20 Dec 2011

ESC welcomes the US study that explores PCI readmissions

The European Society of Cardiology (ESC) welcomes the spotlight that a US study has placed on the importance of measuring rates of rehospitalisation following percutaneous coronary intervention (PCI) procedures.

20 Dec 2011

Gene therapy may promote growth of hair cells in inner ear

Normal hearing depends on the presence of healthy hair cells in the inner ear. Gene therapy has the potential to slow the loss of hair cells and promote the growth of hair cells that have already been damaged.

20 Dec 2011

Viewpoints: Is Wyden-Ryan Medicare plan a game changer?; The GOP and the individual mandate

In the maelstrom of dysfunction and partisanship better known as the 112th Congress, it is always surprising and gratifying when lawmakers from opposing parties manage to work together. That is particularly true when their collaboration involves an issue as politically charged and substantively complex as Medicare. So we begin by congratulating Sen. Ron Wyden (D-Ore.) and Rep. Paul Ryan (R-Wis.) for having the tenacity to try again, with a revamped version of Medicare reform unveiled last week.

20 Dec 2011

Smoking in women associated with skin cancer: Study

A new study has found a link between tobacco use and skin cancer especially in women. The study found that women who had squamous cell skin cancer were more likely to have smoked than those who were free from the disease. And those who smoked at least 20 years were twice as likely to develop squamous cell skin cancer - a less aggressive form of skin cancer as melanoma.

19 Dec 2011

Phase I clinical study of Selexys SelG1 for sickle cell disease completed

Selexys Pharmaceuticals announced today that it has completed a Phase I clinical study of its lead compound SelG1, an antibody specific for the pro-inflammatory cell adhesion molecule P-selectin.

19 Dec 2011

Individualised approach to cancer medicine considering genetic variations

A new cancer research centre established at the University of Adelaide will focus on treatment options tailored to the individual, taking into account DNA and genetic variations between people.

19 Dec 2011

Exactech commences clinical trial to evaluate new cartilage repair technology

Exactech, Inc., a developer and producer of bone and joint restoration products for hip, knee, shoulder, spine and biologic materials announced today it has initiated a prospective, randomized, multi-center, clinical trial to evaluate the safety and effectiveness of a new cartilage repair technology.

19 Dec 2011

UCL awarded 20M grant to establish The Leonard Wolfson Experimental Neurology Centre

A new centre dedicated to the understanding and treatment of neurodegenerative diseases will be established at UCL following the award of a -20million grant from the Wolfson Foundation, it was announced today.

19 Dec 2011