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Over-expression of NEK2 in cancer cells significantly enhances drug resistance

Increased NEK2 gene expression linked to increased drug resistance, faster cancer growth, and poorer patient outcome - The finding may improved diagnostic and prognostic tools for cancer care and could lead to improved cancer therapies

16 Jan 2013

Functionally deaf patients can gain normal hearing with new implant that replaces the middle ear

Functionally deaf patients can gain normal hearing with a new implant that replaces the middle ear. The unique invention from the Chalmers University of Technology has been approved for a clinical study. The first operation was performed on a patient in December 2012.

15 Jan 2013

Novel system could allow broader screening for esophageal cancer, other conditions

Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) have developed an imaging system enclosed in a capsule about the size of a multivitamin pill that creates detailed, microscopic images of the esophageal wall. The system has several advantages over traditional endoscopy.

15 Jan 2013

Children with chronic medical conditions more likely to use alternative medicine

Children who regularly see specialists for chronic medical conditions are also using complementary medicine at a high rate, demonstrates recently published research from the University of Alberta and the University of Ottawa.

15 Jan 2013

Obese youngsters at far greater risk than had been supposed

While a great deal of research on childhood obesity has spotlighted the long-term health problems that emerge in adulthood, a new UCLA study focuses on the condition's immediate consequences and shows that obese youngsters are at far greater risk than had been supposed.

15 Jan 2013

Aggressive breast cancer’s metastasis molecular switch identified

Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor and metastasize throughout the body. Their findings, published in Cancer Cell, suggest a novel approach for developing agents to treat cancer once it has spread.

15 Jan 2013

Knee cartilage repair success with new biomaterial

In a small study, researchers reported increased healthy tissue growth after surgical repair of damaged cartilage if they put a “hydrogel” scaffolding into the wound to support and nourish the healing process. The squishy hydrogel material was implanted in 15 patients during standard microfracture surgery, in which tiny holes are punched in a bone near the injured cartilage. The holes stimulate patients’ own specialized stem cells to emerge from bone marrow and grow new cartilage atop the bone.

15 Jan 2013

Dementia care services: an interview with Sue McLean

The term 'dementia' is used to describe symptoms that occur when the brain is affected by specific diseases and conditions, such as Alzheimer’s disease, vascular dementia, Lewy Bodies or Korsakoff’s syndrome.

From Community Integrated Care 15 Jan 2013

Smoking intensity affects course of bladder cancer

Smoking not only causes bladder cancer—it also affects its course, in that people who smoke more have greater likelihood of developing more aggressive and deadly disease. That is one of the conclusions of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The study also found that a panel of bladder cancer markers can predict which particular cases are at the highest risk for a fatal outcome.

14 Jan 2013

Repression of PTB protein in fibroblasts can convert pluripotent stem cells into functional neurons

Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells - abundantly found in connective tissues - into functional neurons. The findings, which could have far-reaching implications for the development of new treatments for neurodegenerative diseases like Huntington's, Parkinson's and Alzheimer's, will be published online in advance of the January 17 issue of the journal Cell.

11 Jan 2013

Angiotensin II blockade does not seem to provide benefit to kidney transplant recipients

A drug that protects the kidneys of patients with chronic kidney disease does not seem to provide the same benefit to kidney transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

11 Jan 2013

Fiscal cliff boosts clinical data registries, but cuts some health care payments

CQ HealthBeat reports on a provision of the fiscal cliff law intended to encourage physicians to submit data to registries that could be a tool to promote better quality care. The Medicare NewsGroup analyzes another provision that changes how payments are calculated for end stage renal disease drugs.

11 Jan 2013

Scientists track electrical signals in the brain region linked to spatial awareness

Research at the University of Edinburgh tracked electrical signals in the part of the brain linked to spatial awareness.

11 Jan 2013

Baboon embryonic stem cells can be programmed to completely restore severely damaged arteries

Scientists at the Texas Biomedical Research Institute have for the first time demonstrated that baboon embryonic stem cells can be programmed to completely restore a severely damaged artery. These early results show promise for eventually developing stem cell therapies to restore human tissues or organs damaged by age or disease.

11 Jan 2013

Blocking interaction of JNK enzyme may counteract neuron destruction

Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer's disease, Amyotrophic Lateral Sclerosis and Parkinson's disease.

11 Jan 2013

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.

11 Jan 2013

Young humans capable of generating new heart muscle cells

Researchers at Boston Children's Hospital have found, for the first time that young humans (infants, children and adolescents) are capable of generating new heart muscle cells.

11 Jan 2013

Lower liver quality from donation after cardiac death linked to drop in transplants

A new study, funded in part by the National Institutes of Health (NIH) and Health Resources and Services Administration, and published in the January 2013 issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases (AASLD), found that the non-use of donor livers climbed through 2010 due to a worsening of donor liver quality, primarily from donation following cardiac death. Diabetes, donor age, and body mass index (BMI) were also linked to a decrease in use of organs.

11 Jan 2013

Placing peanut protein under a patient's tongue helps dampen allergic reactions

Of all foods, peanuts are the most frequent cause of life-threatening and fatal allergic reactions. New research at National Jewish Health provides additional support for a strategy to reduce the severity of reactions to peanut- repeatedly consuming small amounts of the very food that causes those reactions in the first place, a practice called immunotherapy.

11 Jan 2013

Melanomas that develop resistance to vemurafenib also become addicted to the drug

Researchers in California and Switzerland have discovered that melanomas that develop resistance to the anti-cancer drug vemurafenib (marketed as Zelboraf), also develop addiction to the drug, an observation that may have important implications for the lives of patients with late-stage disease.

11 Jan 2013

Medical Condition News

Over-expression of NEK2 in cancer cells significantly enhances drug resistance

Functionally deaf patients can gain normal hearing with new implant that replaces the middle ear

Novel system could allow broader screening for esophageal cancer, other conditions

Children with chronic medical conditions more likely to use alternative medicine

Obese youngsters at far greater risk than had been supposed

Aggressive breast cancer’s metastasis molecular switch identified

Knee cartilage repair success with new biomaterial

Dementia care services: an interview with Sue McLean

Smoking intensity affects course of bladder cancer

Repression of PTB protein in fibroblasts can convert pluripotent stem cells into functional neurons

Angiotensin II blockade does not seem to provide benefit to kidney transplant recipients

Fiscal cliff boosts clinical data registries, but cuts some health care payments

Scientists track electrical signals in the brain region linked to spatial awareness

Baboon embryonic stem cells can be programmed to completely restore severely damaged arteries

Blocking interaction of JNK enzyme may counteract neuron destruction

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

Young humans capable of generating new heart muscle cells

Lower liver quality from donation after cardiac death linked to drop in transplants

Placing peanut protein under a patient's tongue helps dampen allergic reactions

Melanomas that develop resistance to vemurafenib also become addicted to the drug

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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