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Challenges in treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a rare progressive liver disease that damages bile ducts and significantly increases the risk of bile duct cancer, particularly a type called cholangiocarcinoma (CCA).

20 Jun 2024

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals - Mass Eye and Ear and Massachusetts General Hospital (MGH) - reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.

20 Jun 2024

Walking reduces recurrence of low back pain, study finds

Adults with a history of low back pain went nearly twice as long without a recurrence of their back pain if they walked regularly, a world-first study has found.

20 Jun 2024

Doctors may soon be able to use AI for cancer detection

A new paper in Biology Methods & Protocols, published by Oxford University Press, indicates that it may soon be possible for doctors to use artificial intelligence (AI) to detect and diagnose cancer in patients, allowing for earlier treatment.

20 Jun 2024

Exercising at night improves glucose control in overweight adults

Researchers explore differences in the timing physical activity and its impact on blood glucose levels and metabolic function.

20 Jun 2024

High-fat diet triggers anxiety in male rats through gut-brain axis disruption

Researchers investigate the impact of a high-fat diet on gut microbiome diversity and its effects on anxiety-related symptoms.

20 Jun 2024

Young adults with periodontitis at higher risk for cryptogenic ischemic stroke

Periodontitis, a common condition, has been linked to a specific type of ischemic stroke.

20 Jun 2024

Yeast-fermented bread shows promise in preventing asthma symptoms

The effects of a functional bread fermented with yeast (Saccharomyces cerevisiae) in asthma prevention.

20 Jun 2024

Study reveals cognitive benefits of ketogenic diet in aged mice

The impact of cyclic ketogenic diet treatments in improving the age-related decline in brain function.

20 Jun 2024

Non-chemotherapy treatment regimen achieves full remission in aggressive B-cell lymphoma

Researchers at the National Institutes of Health (NIH) have developed a non-chemotherapy treatment regimen that is achieving full remissions for some people with aggressive B-cell lymphoma that has come back or is no longer responding to standard treatments.

19 Jun 2024

Enlarged prostate medications may also decrease the risk for dementia with Lewy bodies

A new study suggests that certain drugs commonly used to treat enlarged prostate may also decrease the risk for dementia with Lewy bodies (DLB).

19 Jun 2024

New cellular atlas revolutionizes understanding of spinal cord injury

Scientists at EPFL have achieved a significant research milestone in the field of spinal cord injuries - mapping out the cellular and molecular dynamics of paralysis in unprecedented detail with their open-source project 'Tabulae Paralytica'.

19 Jun 2024

Innovative collar device for detecting sleep apnea in dogs at home

A doctoral study completed at the University of Helsinki investigated the diagnostic possibilities for canine sleep apnea, as well as its predisposing risk factors and potential symptoms.

19 Jun 2024

AI-driven blood test offers hope for early Parkinson's diagnosis

A team of researchers, led by scientists at UCL and University Medical Center Goettingen, Germany, have developed a simple blood test that uses artificial intelligence (AI) to predict Parkinson's up to seven years before the onset of symptoms.

19 Jun 2024

Improving stroke survivor health outcomes through home safety interventions

Researchers at Washington University School of Medicine in St. Louis have found that safety interventions - such as walkers, grab bars, ramps and other home modifications - allow many stroke survivors to keep living independently in their homes and may reduce their risk of death.

19 Jun 2024