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New hope for GI cancers: Review analyzes molecular targets and treatment advancements

Gastrointestinal (GI) cancers, encompassing esophageal, gastric, small bowel, and colorectal carcinomas, represent a significant global health burden due to their high incidence and mortality rates.

18 Jun 2024

Gprc5a identified as potential drug target for treating osteoporosis

Osteoporosis is a skeletal condition that leads to the weakening of bones, making them porous, fragile, and prone to breakage.

18 Jun 2024

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing alpha-synuclein.

18 Jun 2024

Cancer survivors are at greater risk for cardiovascular diseases, other cancers

Swedish researchers have surveyed all people under the age of 25 who have had cancer since 1958. The study, led by researchers at Linköping University and Region Östergötland, shows that cancer survivors are at greater risk for cardiovascular diseases, other cancers and other diagnoses later in life.

18 Jun 2024

Mitophagy fuels cancer stem cell growth and survival

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, "Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration."

18 Jun 2024

EULAR updates PRP guidelines: Enhancing patient involvement in rheumatic disease research

In recent years, the benefits of involving PRPs has increasing been recognized. The role is an important one, which goes well beyond the inclusion of patients as study participants.

18 Jun 2024

New research explores maternal influence on brain biomarkers

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences risk of biological changes in the brain that lead to disease. By evaluating 4,400 cognitively unimpaired adults ages 65-85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains. Their results are published in JAMA Neurology.

18 Jun 2024

Precise protein design offers hope for damaged hearts and kidneys

Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope for repairing damaged hearts, kidneys, and other organs.

18 Jun 2024

Amoxicillin outperforms penicillin V in treating pediatric pneumonia, study finds

A recent study confirmed amoxicillin's lower risk of treatment failure compared to penicillin V in treating pediatric pneumonia, with no difference in severe complications.

18 Jun 2024

AI technology offers hope for faster stroke detection

Strokes, which affect millions of people globally, occur when the blood supply to part of the brain is interrupted or reduced, which prevent brain tissue from getting oxygen and nutrients. A few minutes of delay can result in permanent damage to the brain cells.

18 Jun 2024

Safety-focused summary of GLP-1 receptor agonists in diabetes, obesity, and beyond

A recent review in Diabetes Care evaluates the efficacy and safety of GLP-1 receptor agonists for type 2 diabetes and obesity, exploring their potential for new medical indications.

18 Jun 2024

New AI tool could revolutionize clinical trial efficiency and cost

Generative Artificial Intelligence (Gen AI) can rapidly and accurately screen patients for clinical trial eligibility, according to a new study from Mass General Brigham researchers. Such technology could make it faster and cheaper to evaluate new treatments and, ultimately, help bring successful ones to patients.

17 Jun 2024

New technique uses nutrients to effectively treat cancer

An international research team has discovered a new way to effectively treat cancer, by using nutrients to reactivate suppressed metabolic pathways in cancer cells.

17 Jun 2024

Rapid test detects brain cancer mutations in cerebrospinal fluid

A test that looks for genetic hallmarks of brain cancers in samples of cerebrospinal fluid can decrease the time to diagnosis and eliminate the need for invasive brain biopsies for some patients.

17 Jun 2024

Daily loneliness linked to increased physical symptoms in middle age, study finds

Daily loneliness significantly impacts physical health in middle-aged adults, leading to increased symptoms like headaches and nausea. Variability in loneliness correlates with higher symptom severity, emphasizing the need for stable social connections.

17 Jun 2024

9/11 first responders face increased midlife dementia risk from severe dust exposure

Severe dust exposure among World Trade Center responders is linked to higher rates of dementia before age 65, highlighting long-term cognitive risks from 9/11.

17 Jun 2024

Revolutionary anti-ceramide immunotherapy could prevent blindness in diabetic patients

Patients with diabetes face a host of potential health problems as they work to manage the chronic disease.

17 Jun 2024

Innovative bread formulation shows promise in preventing asthma

Brazilian researchers have developed functional bread with the potential to prevent asthma, a respiratory disorder responsible for some 350,000 hospitalizations per year in the SUS (Sistema Único de Saúde), the nation's public healthcare network.

17 Jun 2024

Protein aggregation: A new frontier in age-related disease detection

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU), who are also adjunct directors at the Institute of Molecular Biology (IMB) in Mainz, propose the concept of a "protein aggregation clock" to measure aging and health in a new perspective article published in Nature Cell Biology.

17 Jun 2024

Newly designed genetic therapy could alleviate debilitating giant moles in rare skin condition

Researchers at the Francis Crick Institute, UCL Great Ormond Street Institute for Child Health and Great Ormond Street Hospital for Children (GOSH) have designed a new genetic therapy that could alleviate debilitating giant moles in a rare skin condition.

17 Jun 2024

Medical Condition News

New hope for GI cancers: Review analyzes molecular targets and treatment advancements

Gprc5a identified as potential drug target for treating osteoporosis

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

Cancer survivors are at greater risk for cardiovascular diseases, other cancers

Mitophagy fuels cancer stem cell growth and survival

EULAR updates PRP guidelines: Enhancing patient involvement in rheumatic disease research

New research explores maternal influence on brain biomarkers

Precise protein design offers hope for damaged hearts and kidneys

Amoxicillin outperforms penicillin V in treating pediatric pneumonia, study finds

AI technology offers hope for faster stroke detection

Safety-focused summary of GLP-1 receptor agonists in diabetes, obesity, and beyond

New AI tool could revolutionize clinical trial efficiency and cost

New technique uses nutrients to effectively treat cancer

Rapid test detects brain cancer mutations in cerebrospinal fluid

Daily loneliness linked to increased physical symptoms in middle age, study finds

9/11 first responders face increased midlife dementia risk from severe dust exposure

Revolutionary anti-ceramide immunotherapy could prevent blindness in diabetic patients

Innovative bread formulation shows promise in preventing asthma

Protein aggregation: A new frontier in age-related disease detection

Newly designed genetic therapy could alleviate debilitating giant moles in rare skin condition

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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