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Scientists decode signals that boost the burning of fat

The numbers of obese people are climbing steeply all over the world - with obvious major consequences for their health. Due to excess food intake and a lack of physical activity, but also due to genetic factors, the risk for overweight people dying from diseases like coronary heart disease, diabetes und atherosclerosis increases.

29 Aug 2012

Risk of stroke after myocardial infarction seems to decrease with improvements in coronary care

The analysis of data from two Swedish registries was presented by Dr Anders Ulvenstam, and suggests that the reduction is due to improvements in AMI care.

29 Aug 2012

Esperance completes EP 100 and paclitaxel Phase 2 combination trial on advanced ovarian cancer

Esperance Pharmaceuticals today announced the completion of the run-in cohort of its Phase 2, randomized, multi‐center trial of EP‑100 in combination with paclitaxel for patients with advanced ovarian cancer. EP‐100 is a targeted membrane‐disrupting peptide (tMDP) designed to seek and destroy cancer cells that overexpress luteinizing hormone releasing hormone (LHRH) receptors on their surfaces.

29 Aug 2012

Catheter ablation for Afib is safe and suppresses arrhythmia recurrences

Catheter ablation for atrial fibrillation (Afib) is safe and suppresses arrhythmia recurrences in 74% of patients after a single procedure, according to results from the one-year follow-up of the Atrial Fibrillation Ablation Pilot Study, the first European registry to evaluate the real-life epidemiology of catheter ablation for AFib.

29 Aug 2012

Ultra-fast 320-detector CT scanner can accurately diagnose arterial blockages

An ultra-fast, 320-detector computed tomography (CT) scanner can accurately sort out which people with chest pain need - or don't need - an invasive procedure such as cardiac angioplasty or bypass surgery to restore blood flow to the heart, according to an international study. Results of the study, which involved 381 patients at 16 hospitals in eight countries, are scheduled to be presented at the European Society of Cardiology Congress in Munich, Germany, on August 28.

29 Aug 2012

Scientists identify genes that underlie growth of primitive leukemia stem cells

University of Rochester Medical Center scientists believe they are the first to identify genes that underlie the growth of primitive leukemia stem cells, and then to use the new genetic signature to identify currently available drugs that selectively target the rogue cells.

29 Aug 2012

Top-line results from Rexahn’s Archexin Phase II study on metastatic pancreatic cancer

Rexahn Pharmaceuticals, Inc., a clinical stage biopharmaceutical company focused on developing multi-indication therapeutics in oncology and CNS, today announced top-line results from a Phase II clinical study of Archexin, its clinical-stage oncology drug candidate.

29 Aug 2012

Addition of CTP to CT angiography allows clinicians to identify flow-limiting coronary artery disease

A non-invasive imaging strategy which integrates non-invasive CT angiography (CTA) and CT myocardial perfusion imaging (CTP) has robust diagnostic accuracy for identifying patients with flow-limiting coronary artery disease in need of myocardial revascularisation, according to results of the CORE320 study presented here today by Dr Joao AC Lima from Johns Hopkins Hospital, Baltimore, USA.

29 Aug 2012

St. Jude’s EnligHTN renal denervation system safe and effective in treating resistant hypertension

St. Jude Medical, Inc., a global medical device company, today announced that interim data demonstrated the company's EnligHTN renal denervation system is safe and effective for the treatment of resistant hypertension.

29 Aug 2012

Study looks at exercise habits among cancer patients

Numerous studies have shown the powerful effect that exercise can have on cancer care and recovery. For patients who have gone through breast or colon cancer treatment, regular exercise has been found to reduce recurrence of the disease by up to 50 percent.

29 Aug 2012

VA report shows improvement in gender disparities in 12 out of 14 HEDIS measures

The Department of Veterans Affairs (VA) has released a report that shows improvement in gender disparities in 12 out of 14 Healthcare Effectiveness Data and Information Set (HEDIS) measures in VA since 2008.

29 Aug 2012

One in four women experience vulvar pain at some point in their lifetime

According to a study conducted by the University of Michigan, one in four women experience vulvar pain at some point in their lifetime. Like all medical concerns, vulvar pain causes both physical and mental stress. Additionally, vulvar pain can have an adverse effect on intimacy and relationships.

29 Aug 2012

Cyclin D3 protein regulates size and quantity of RBCs

The adult human circulatory system contains between 20 and 30 trillion red blood cells (RBCs), the precise size and number of which can vary from person to person. Some people may have fewer, but larger RBCs, while others may have a larger number of smaller RBCs. Although these differences in size and number may seem inconsequential, they raise an important question: Just what controls these characteristics of RBCs?

29 Aug 2012

Elixir Medical’s DESyne BD Novolimus Eluting Coronary Stent System receives CE Mark approval

Elixir Medical Corporation, a developer of product platforms that combine state-of-the-art medical devices with advanced pharmaceuticals, announced that it has received CE Mark approval for its DESyne BD Novolimus Eluting Coronary Stent System for the treatment of coronary artery disease.

29 Aug 2012

GeneTex to introduce new antibody against hypoxia-inducible factor 1alpha

GeneTex, Inc., a leading manufacturer of antibodies, has announced that they will be launching a new antibody against HIF1a (hypoxia-inducible factor 1alpha).

29 Aug 2012

Altheus Therapeutics initiates enrollment in Zoenasa Phase 2 study for ulcerative colitis

Altheus Therapeutics announced today it has randomized its first patient in a comparator-controlled Phase 2 efficacy study of Zoenasa, a novel combination therapy for ulcerative colitis (UC).

29 Aug 2012

Aeterna Zentaris commences enrollment in AEZS-130 Phase 2A trial for cancer cachexia

Aeterna Zentaris Inc. today announced that a first patient has been recruited for a Phase 2A trial with its ghrelin agonist, AEZS-130 in patients with cancer cachexia.

28 Aug 2012

Study raises cautionary note about preferential use of endovascular technique for ruptured AAA

A new study raises a cautionary note about the increasing use of a minimally invasive procedure to repair ruptured abdominal aortic aneurysms, according to vascular surgeon Dr. Jae Sung Cho of Loyola University Medical Center.

28 Aug 2012

Oxford University Press announces acquisition of American Journal of Hypertension

Oxford University Press (OUP) today announced that the esteemed American Journal of Hypertension will be joining the publisher's journal collection.

28 Aug 2012

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

Pulmatrix, Inc., a clinical stage biotechnology company creating novel inhaled therapeutics, announced today that three posters on its lead iCALM therapeutic, the first treatment developed utilizing its iSPERSE inhaled drug platform, will be presented at the European Respiratory Society (ERS) Annual Congress taking place September 1-5, 2012, in Vienna, Austria.

28 Aug 2012

Medical Condition News

Scientists decode signals that boost the burning of fat

Risk of stroke after myocardial infarction seems to decrease with improvements in coronary care

Esperance completes EP 100 and paclitaxel Phase 2 combination trial on advanced ovarian cancer

Catheter ablation for Afib is safe and suppresses arrhythmia recurrences

Ultra-fast 320-detector CT scanner can accurately diagnose arterial blockages

Scientists identify genes that underlie growth of primitive leukemia stem cells

Top-line results from Rexahn’s Archexin Phase II study on metastatic pancreatic cancer

Addition of CTP to CT angiography allows clinicians to identify flow-limiting coronary artery disease

St. Jude’s EnligHTN renal denervation system safe and effective in treating resistant hypertension

Study looks at exercise habits among cancer patients

VA report shows improvement in gender disparities in 12 out of 14 HEDIS measures

One in four women experience vulvar pain at some point in their lifetime

Cyclin D3 protein regulates size and quantity of RBCs

Elixir Medical’s DESyne BD Novolimus Eluting Coronary Stent System receives CE Mark approval

GeneTex to introduce new antibody against hypoxia-inducible factor 1alpha

Altheus Therapeutics initiates enrollment in Zoenasa Phase 2 study for ulcerative colitis

Aeterna Zentaris commences enrollment in AEZS-130 Phase 2A trial for cancer cachexia

Study raises cautionary note about preferential use of endovascular technique for ruptured AAA

Oxford University Press announces acquisition of American Journal of Hypertension

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

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