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XJB-5-131 prevents secondary damage of severe traumatic brain injury

Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been impaired, according to a research team from the University of Pittsburgh School of Medicine, Graduate School of Public Health and Department of Chemistry in a report published online today in Nature Neuroscience.

27 Aug 2012

EC grants marketing authorization to Meda's Zyclara for treatment of actinic keratosis

Meda announced today that the European Commission (EC) has granted marketing authorization for Zyclara in the European Union. Zyclara (imiquimod 3.75% cream) is a patented product for the treatment of actinic keratosis.

27 Aug 2012

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

New data to be presented at the Annual Congress of the European Respiratory Society (ERS 2012), in Vienna, Austria, will shed light on the current and potential future role of tiotropium, the first once-daily long-acting inhaled anticholinergic for patients with Chronic Obstructive Pulmonary Disease (COPD).

27 Aug 2012

Profilin-1 gene influences survival time in Lou Gehrig's disease

A team of scientists, including faculty at the University of Massachusetts Medical School (UMMS), have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

27 Aug 2012

People with cardiac arrest during or shortly after exercise more likely to survive

People who have a cardiac arrest during or shortly after exercise are three times more likely to survive than those who have a cardiac arrest that is not exercise related, according to research presented at the ESC Congress 2012 today.

27 Aug 2012

Study confirms electrical storm as potent risk factor for death and impaired quality of life

Electrical storm (ES) is a potent risk factor for mortality and morbidity, according to research presented today at the ESC Congress 2012 by Dr Federico Guerra from Italy. Data was also presented on which patients are prone to developing ES and how effective current treatments are.

27 Aug 2012

Cardiovascular screening with ECG in young athletes is cost effective

Cardiovascular screening with ECG in young athletes is a cost effective way of diagnosing cardiac abnormalities, at just 138 Swiss Francs (about €115) per athlete. The findings were presented today at the ESC Congress 2012 by Dr Andrea Menafoglio from Switzerland.

27 Aug 2012

Genzyme receives Refuse to File letter from FDA for LEMTRADA

Genzyme, a Sanofi company, announced it has received a Refuse to File letter from the U.S. Food and Drug Administration (FDA) in response to the supplemental Biologics License Application (sBLA) for the approval of LEMTRADA (alemtuzumab) as a treatment for relapsing multiple sclerosis.

27 Aug 2012

Female sex associated with increased risk of stroke for AF patients aged ≥75 years

Female gender increases the risk of stroke in patients with atrial fibrillation (AF) aged >75 years by 20%, according to a study presented today at the ESC Congress 2012. The findings were presented by Anders Mikkelsen, from Denmark.

27 Aug 2012

$LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction$

LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction

The novel angiotensin receptor neprilysin inhibitor, LCZ696, demonstrated beneficial effects in heart failure patients with preserved ejection fraction (HFpEF), according to results of the PARAMOUNT (Prospective compArison of ARNI with ARB on Management Of heart failUre with preserved ejectioN fracTion) trial.

27 Aug 2012

People with guanine version of rs55705857 SNP more likely to develop gliomas

People who carry a "G" instead of an "A" at a specific spot in their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, a Mayo Clinic and University of California, San Francisco study has found. The

27 Aug 2012

Results from Roche's trastuzumab emtansine Phase III trial on HER2-positive breast cancer

ImmunoGen, Inc., a biotechnology company that develops anticancer products using its Targeted Antibody Payload (TAP) technology and antibody expertise, today announced that Roche has reported that updated results from its EMILIA Phase III trial show that patients treated with trastuzumab emtansine had a significant improvement in OS compared to those randomized to standard-of-care therapy.

27 Aug 2012

$Noninvasive fractional flow reserve superior to CT in identifying individuals with ischemia$

Noninvasive fractional flow reserve superior to CT in identifying individuals with ischemia

Among patients with suspected or known coronary artery disease, use of a method that applies computational fluid dynamics to derive certain data from computed tomographic (CT) angiography demonstrated improved diagnostic accuracy vs. CT angiography alone for the diagnosis of ischemia, according to a study being published online by JAMA.

27 Aug 2012

Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death

The first trial to study patients with acute coronary syndrome who do not undergo coronary stenting or bypass surgery found no significant difference between two anti-clotting drugs - prasugrel and clopidogrel - in preventing the first occurrence of death, heart attack or stroke, according to Duke University Medical Center cardiologists.

27 Aug 2012

Study investigates effects of passive smoking on the levels of three parameters

"It is well known that passive smoking is harmful for cardiovascular health, but the mechanism has not yet been discovered," said Dr Kaya. "We investigated the effects of passive smoking on the levels of three parameters - mean platelet volume (MPV), carboxyhemoglobin (COHb) and lactate - in an effort to further understand this mechanism. We also looked at the correlation between the three parameters."

27 Aug 2012

Essential Learning announces new partnership with Hazelden

Essential Learning, the leading provider of e-learning solutions to the behavioral health and human service industries, is pleased to announce a new partnership with Hazelden, a nonprofit organization for addiction treatment and publisher of treatment, behavioral health and youth violence educational resources.

27 Aug 2012

New non-invasive brain scan can benefit patients with epileptic seizures

A team of University of Minnesota biomedical engineers and researchers from Mayo Clinic published a groundbreaking study today that outlines how a new type of non-invasive brain scan taken immediately after a seizure gives additional insight into possible causes and treatments for epilepsy patients.

27 Aug 2012

MedQIA develops new software that forms the basis of Imaging Biomarker Information System

MedQIA has developed a software toolkit of image analysis routines that forms the basis of an Imaging Biomarker Information System (IBIS).

27 Aug 2012

New molecular mechanism plays a crucial role in inhibiting TGF-beta signaling

Researchers headed by Maria Macias an ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona) and Joan Massagu-, a Howard Hughes Medical Institute investigator at Memorial Sloan-Kettering Cancer Center (MSKCC) in New York, have identified a new molecular mechanism that plays a crucial role in the control of the activation of certain genes associated with cancer.

27 Aug 2012

Patients tend to have worse outcomes when GBM appears in more than one location

When aggressive, malignant tumors appear in more than one location in the brain, patient survival tends to be significantly shorter than when the disease starts as a single tumor, even though patients in both groups undergo virtually identical treatments, according to research at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Research Institute.

27 Aug 2012

Medical Condition News

XJB-5-131 prevents secondary damage of severe traumatic brain injury

EC grants marketing authorization to Meda's Zyclara for treatment of actinic keratosis

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

Profilin-1 gene influences survival time in Lou Gehrig's disease

People with cardiac arrest during or shortly after exercise more likely to survive

Study confirms electrical storm as potent risk factor for death and impaired quality of life

Cardiovascular screening with ECG in young athletes is cost effective

Genzyme receives Refuse to File letter from FDA for LEMTRADA

Female sex associated with increased risk of stroke for AF patients aged ≥75 years

LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction

People with guanine version of rs55705857 SNP more likely to develop gliomas

Results from Roche's trastuzumab emtansine Phase III trial on HER2-positive breast cancer

Noninvasive fractional flow reserve superior to CT in identifying individuals with ischemia

Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death

Study investigates effects of passive smoking on the levels of three parameters

Essential Learning announces new partnership with Hazelden

New non-invasive brain scan can benefit patients with epileptic seizures

MedQIA develops new software that forms the basis of Imaging Biomarker Information System

New molecular mechanism plays a crucial role in inhibiting TGF-beta signaling

Patients tend to have worse outcomes when GBM appears in more than one location

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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