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Article describes immune-related adverse events with newly approved melanoma drug

An internationally recognized melanoma researcher at Moffitt Cancer Center and colleagues at the University of Kiel in Germany, including Axel Hauschild, M.D. and Katharina C. K-hler, M.D., have published an article in the current issue of The Journal of Clinical Oncology that describes immune-related adverse events for patients receiving either tremelimumab or ipilimumab, the latter a drug approved last year by the U.S. Food and Drug Administration for treating metastatic melanoma and other cancers.

23 Aug 2012

Power Over Pressure steering committee launches world's first hypertension online resource

The Power Over Pressure steering committee today announced the launch of the world's first online resource created to help healthcare professionals improve diagnosis and develop solutions for treatment-resistant hypertension, an urgent and growing public health issue that affects 120 million people worldwide.

23 Aug 2012

Study provides new direction for research in bipolar disorder during pregnancy

The impact of bipolar disorder during pregnancy has been hotly contended among the research community. Now, a new study from Lawson Health Research Institute and Western University is sorting out the debate and calling for more targeted, prospective research.

23 Aug 2012

New results describe development of DC cancer vaccine with enhanced immunogenic potential

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators at Radboud University Nijmegen Medical Centre in the Netherlands announced today that they have published new pre-clinical results in the journal Cancer Immunology Immunotherapy describing the development of a dendritic cell (DC) cancer vaccine with enhanced immunogenic potential.

23 Aug 2012

Statin's potency may cause muscle problems in patients with cardiovascular disease

A study from the University of California, San Diego School of Medicine, published August 22 online by PLoS ONE, reports that muscle problems reported by patients taking statins were related to the strength or potency of the given cholesterol-lowering drugs.

23 Aug 2012

Preemptive cognitive training can help the brain function normally later in life

Preemptive cognitive training—an early intervention to address neuropsychiatric deficiencies—can help the brain function normally later in life, a team of researchers has found through a series of experiments on laboratory rats.

23 Aug 2012

Study might help solve the biggest mystery of Parkinson’s

The recent discoveries that α-Synuclein(α-Syn) protein, a central player in Parkinson´s disease (PD) brain destruction, could not only pass from one neuron to another but also exist outside neuronal cells has led to major rethink on the disease.

23 Aug 2012

Two Penn Medicine hospitals receive Primary Stroke Center certification from The Joint Commission

Two Penn Medicine hospitals have received Primary Stroke Center certification from The Joint Commission for efforts to achieve long-term success in improving outcomes for stroke patients.

23 Aug 2012

Epigallocatechin gallate can shrink cancerous tumours

A compound found in green tea could be a weapon in treatments for tackling cancer, according to newly-published research at the University of Strathclyde in Glasgow, Scotland.

23 Aug 2012

Laminin-111 protein therapy could treat Duchenne muscular dystrophy

A novel treatment in development at the University of Nevada School of Medicine for the most common form of muscular dystrophy is advancing towards human trials with a $308,000 boost from the Muscular Dystrophy Association.

23 Aug 2012

Newly discovered on/off switch in enzymes may help battle fat-related disease

Enzymes involved in breaking down fat can now be manipulated to work three times harder by turning on a molecular switch recently observed by chemists at the University of Copenhagen. Being able to control this chemical on/off button could have massive implications for curing diseases related to obesity including diabetes, cardio vascular disease, stroke and even skin problems like acne. But the implications may be wider.

23 Aug 2012

NIH awards $100,000 STTR Phase I Grant to Transgenomic for pancreatic cancer research

Transgenomic, Inc. today announced it has been awarded a $100,000 Small Business Technology Transfer Program (STTR) Phase I Grant by the National Institutes of Health's National Center For Advancing Translational Sciences.

23 Aug 2012

Simple eye tracking test could hold key to early Alzheimer's diagnosis

A simple eye tracking test could hold the key to earlier Alzheimer's diagnosis, according to new research published today in the Journal of the American Aging Association.

23 Aug 2012

One blog examines GAVI Alliance's efforts to accelerate introduction of hepatitis B vaccines in developing countries

"I am looking forward to participating in the 2012 World Cancer Leaders' Summit, to be held in Montreal, Canada on August 27," GAVI Alliance Deputy CEO Helen Evans writes in this post in the One Blog.

23 Aug 2012

TREM-1 gene disrupts inflammatory process implicated in liver cancer

Researchers at the Georgia Health Sciences University Cancer Center have identified a gene that disrupts the inflammatory process implicated in liver cancer.

23 Aug 2012

UMN study shows eating less is about reduced desire and willpower

New research from the University of Minnesota's Carlson School of Management suggests learning how to stop enjoying unhealthy food sooner may play a pivotal role in combating America's obesity problem. The research, published in the Journal of Consumer Research, explores how satiation, defined as the drop in liking during repeated consumption, can be a positive mechanism when it lowers the desire for unhealthy foods.

23 Aug 2012

APSSLH and Maney collaborate to launch Speech, Language and Hearing journal

Starting in 2013 Maney will be collaborating with the Asia Pacific Society for the Study of Speech, Language and Hearing (APSSLH) to launch Speech, Language and Hearing. This is a significant development for both Maney and the Society.

23 Aug 2012

New medical technology improves image quality and reduces radiation

Particle physicists have developed a new medical technology that combines PET and MRI in one. Benefit: Improved image quality and less radiation.

22 Aug 2012

RNA switches can better equip and regulate viruses for many therapeutic applications

Numerous viruses are used in the service of science today. They serve as gene taxis to transfer therapeutic genes into body cells or as therapeutic viruses targeted to infect and destroy cancer cells. For such applications, the viruses are often equipped with additional genes, such as for immune mediators or for proteins inducing programmed cell death. However, these gene products can harm the body if they are released at the wrong moment or at excessive levels.

22 Aug 2012

UC San Diego, iSAEC partner to study genetics of drug induced renal injury

The International Serious Adverse Events Consortium (iSAEC) announced today it will collaborate with the University of California, San Diego School of Medicine and UC San Diego Skaggs School of Pharmacy and Pharmaceutical Science to research the genetics of drug induced renal injury (DIRI).

22 Aug 2012

Medical Condition News

Article describes immune-related adverse events with newly approved melanoma drug

Power Over Pressure steering committee launches world's first hypertension online resource

Study provides new direction for research in bipolar disorder during pregnancy

New results describe development of DC cancer vaccine with enhanced immunogenic potential

Statin's potency may cause muscle problems in patients with cardiovascular disease

Preemptive cognitive training can help the brain function normally later in life

Study might help solve the biggest mystery of Parkinson’s

Two Penn Medicine hospitals receive Primary Stroke Center certification from The Joint Commission

Epigallocatechin gallate can shrink cancerous tumours

Laminin-111 protein therapy could treat Duchenne muscular dystrophy

Newly discovered on/off switch in enzymes may help battle fat-related disease

NIH awards $100,000 STTR Phase I Grant to Transgenomic for pancreatic cancer research

Simple eye tracking test could hold key to early Alzheimer's diagnosis

One blog examines GAVI Alliance's efforts to accelerate introduction of hepatitis B vaccines in developing countries

TREM-1 gene disrupts inflammatory process implicated in liver cancer

UMN study shows eating less is about reduced desire and willpower

APSSLH and Maney collaborate to launch Speech, Language and Hearing journal

New medical technology improves image quality and reduces radiation

RNA switches can better equip and regulate viruses for many therapeutic applications

UC San Diego, iSAEC partner to study genetics of drug induced renal injury

Todd Bauman and Chris Povich

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