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New report analyzes annual trends for biomarker FDA approvals since 2008

"Approval Trends for Biomarker-Based IVD Tests: Realizing the Promise of Personalized Medicine," a new report published by Amplion Research analyzes annual trends for FDA approvals since 2008 with some interesting findings.

27 Nov 2012

Study compares effects of weight loss induced by gastric bypass and banding on metabolic response

Obesity is associated with insulin resistance and type 2 diabetes, both of which can be significantly improved by weight loss. Gastric bypass and adjustable gastric banding are two bariatric surgery techniques that are frequently used to effect weight loss in obese patients, but it is unclear if the two procedures produce different outcomes.

27 Nov 2012

Antifibrinolytics inhibit glycine receptor activity in the brain and cause seizures

Antifibrinolytic drugs are frequently used to prevent blood loss during surgery, but sometimes cause convulsive seizures. In this issue of the Journal of Clinical Investigation, researchers led by Beverly Orser at the University of Toronto investigated the molecular mechanisms that underlie this side effect.

27 Nov 2012

Paper illuminates importance of PKM2 in cancer development and progression

Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which brain tumors thrive.

26 Nov 2012

CLCA1 molecule plays a special role in the mucus pathway

Respiratory conditions that restrict breathing such as asthma and chronic obstructive pulmonary disease (COPD) are common killers worldwide. But no effective treatments exist to address the major cause of death in these conditions - excess mucus production.

26 Nov 2012

Epilepsy & Behavior Case Reports from Elsevier

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announces the launch of Epilepsy & Behavior Case Reports a new, online-only, Open Access journal devoted to the rapid publication of case reports on the behavioral aspects of seizures and epilepsy.

26 Nov 2012

Researchers discover LSD-1 enzyme as important target for treatment of Ewing sarcoma

Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study by researchers from Huntsman Cancer Institute (HCI) at the University of Utah. The report appears in today's online issue of the journal Oncogene.

26 Nov 2012

Word-training program found to restore key words in some dementia patients

A simple word-training program has been found to restore key words in people with a type of dementia that attacks language and our memory for words.

26 Nov 2012

Chronic suppurative lung disease: an interview with Dr Robyn Marsh

Chronic suppurative lung disease, or CSLD, is used to describe a range of lung diseases characterised by a chronic wet cough and progressive lung damage. We are interested in the non-cystic fibrosis forms of the disease with a focus on bronchiectasis – the severe form of CSLD.

26 Nov 2012

Researchers discover molecular basis for potential cancer preventive effects of vitamin D

A team of researchers at McGill University have discovered a molecular basis for the potential cancer preventive effects of vitamin D. The team, led by McGill professors John White and David Goltzman, of the Faculty of Medicine's Department of Physiology, discovered that the active form of vitamin D acts by several mechanisms to inhibit both the production and function of the protein cMYC.

26 Nov 2012

New therapeutic technique to repair and rebuild muscle for degenerative muscle disorders

A study published today in BioMed Central's open access journal Skeletal Muscle reports of a new therapeutic technique to repair and rebuild muscle for sufferers of degenerative muscle disorders. The therapy brings together two existing techniques for muscle repair - cell transplantation and tissue engineering - specifically, mesoangioblast stem cells delivered via a hydrogel cell-carrier matrix.

26 Nov 2012

First evidence of blood vessel dysfunction found in healthy young people with cystic fibrosis

The first evidence of blood vessel dysfunction has been found in a small cohort of generally healthy young people with cystic fibrosis, researchers report.

26 Nov 2012

Accera commences clinical efficacy trial of AC-1204 for mild-to-moderate Alzheimer's disease

Accera, Inc., a privately-held, commercial-stage, healthcare company focused on the discovery and development of innovative clinical applications to address acute and chronic neurodegenerative diseases, announced today the initiation of a clinical efficacy trial examining the effects of AC-1204 in patients with mild-to-moderate Alzheimer's disease (AD).

26 Nov 2012

Study shows neurobiological mechanisms of how individual risk preferences determine risk perception

Some people live their lives by the motto "no risk - no fun!" and avoid hardly any risks. Others are clearly more cautious and focus primarily on safety when investing and for other business activities. Scientists from the University of Bonn in cooperation with colleagues from the University of Zurich studied the attitudes towards risk in a group of 56 subjects.

26 Nov 2012

USPTO grants patent for galactomannan-based carbohydrate galectin inhibitor compounds

Galectin Therapeutics, the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, today announced that it has received a notice of allowance from the U.S. Patent and Trademark Office for a divisional patent of Patent Number 8,236,780 "Galactose-prolonged polysaccharides in a formulation for antifibrotic therapies".

26 Nov 2012

FDA grants Seattle Genetics orphan drug designation for ADCETRIS to treat mycosis fungoides

Seattle Genetics, Inc. announced today that ADCETRIS (brentuximab vedotin) has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) for the treatment of mycosis fungoides (MF). MF is the most common type of cutaneous T-cell lymphoma (CTCL).

26 Nov 2012

BSD-2000 Hyperthermia System purchased by Cancer Treatment Centers of America

BSD Medical Corporation, a leading provider of medical systems that utilize targeted heat therapy to treat cancer, announced today that the Cancer Treatment Centers of America (CTCA) at Western Regional Medical Center (WRMC), located in Goodyear, Arizona, has purchased a BSD-2000 Hyperthermia System (BSD-2000).

26 Nov 2012

Interim GALAXY Phase 2b lung cancer study results to be presented at APLCC 2012

Synta Pharmaceuticals Corp. announced today that interim results of the Phase 2b portion of the GALAXY program will be presented on November 28, 2012 at 12:15 p.m. (JST) during the "Highlights of Oral Presentations" session at the Fifth Asia Pacific Lung Cancer Conference (APLCC 2012) in Fukuoka City, Japan.

26 Nov 2012

Frankfurt University Hospital implements microwave ablation for treatment of thyroid nodules

The Department of Nuclear Medicine at the Frankfurt University Hospital recently became the first European hospital to use microwaves to ablate thyroid nodules.

26 Nov 2012

Enrollment complete in Tryton's Pivotal IDE Side Branch Stent trial to treat bifurcation lesions

Tryton Medical, Inc., the leading developer of stents designed to definitively treat bifurcation lesions, today announced the completion of enrollment in the TRYTON Pivotal IDE trial evaluating the Tryton Side Branch Stent.

26 Nov 2012

Medical Condition News

New report analyzes annual trends for biomarker FDA approvals since 2008

Study compares effects of weight loss induced by gastric bypass and banding on metabolic response

Antifibrinolytics inhibit glycine receptor activity in the brain and cause seizures

Paper illuminates importance of PKM2 in cancer development and progression

CLCA1 molecule plays a special role in the mucus pathway

Epilepsy & Behavior Case Reports from Elsevier

Researchers discover LSD-1 enzyme as important target for treatment of Ewing sarcoma

Word-training program found to restore key words in some dementia patients

Chronic suppurative lung disease: an interview with Dr Robyn Marsh

Researchers discover molecular basis for potential cancer preventive effects of vitamin D

New therapeutic technique to repair and rebuild muscle for degenerative muscle disorders

First evidence of blood vessel dysfunction found in healthy young people with cystic fibrosis

Accera commences clinical efficacy trial of AC-1204 for mild-to-moderate Alzheimer's disease

Study shows neurobiological mechanisms of how individual risk preferences determine risk perception

USPTO grants patent for galactomannan-based carbohydrate galectin inhibitor compounds

FDA grants Seattle Genetics orphan drug designation for ADCETRIS to treat mycosis fungoides

BSD-2000 Hyperthermia System purchased by Cancer Treatment Centers of America

Interim GALAXY Phase 2b lung cancer study results to be presented at APLCC 2012

Frankfurt University Hospital implements microwave ablation for treatment of thyroid nodules

Enrollment complete in Tryton's Pivotal IDE Side Branch Stent trial to treat bifurcation lesions

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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