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UB researchers develop aniontransporters to trigger cancer cell apoptosis

The journal Accounts of Chemical Research, which has a profound impact on Chemistry and other related sciences, publishes on its current issue the article "Anion Transporters and Biological Systems", signed by Professor Ricardo Pérez Tomás, from the Department of Pathology and Experimental Therapy of the Faculty of Medicine at the University of Barcelona, Roberto Quesada, from the Department of Chemistry of the Sciences Faculty at the University of Burgos, and Philip A. Gale, from the University of Southampton, in the United Kingdom.

22 Apr 2013

Discovery reverses the prevailing model of how dividing cells monitor equal distribution of chromosomes

Ludwig researchers Arshad Desai and Christopher Campbell, a post-doctoral fellow in his laboratory, were conducting an experiment to parse the molecular details of cell division about three years ago, when they engineered a mutant yeast cell as a control that, in theory, had no chance of surviving. Apparently unaware of this, the mutant thrived.

22 Apr 2013

American College of Surgeons grants Outstanding Achievement Award to 79 accredited cancer programs

The Commission on Cancer (CoC) of the American College of Surgeons (ACS) has granted its 2012 Outstanding Achievement Award to a select group of 79 accredited cancer programs throughout the United States.

22 Apr 2013

Two views are necessary in 3D breast screening to ensure cancer is optimally visualized

One view 3D breast screening (tomosynthesis) means less radiation dose and about five seconds less compression, but a study from Yale University, New Haven, CT, found that obtaining both views is necessary to help ensure that a cancer won't be missed.

22 Apr 2013

Single puncture technique safe and effective in intravascular ultrasound-guided inferior vena cava filter placement

One venous puncture, rather than two, is a safe and effective approach to intravascular ultrasound-guided inferior vena cava filter placement in critically-ill patients, a new study shows.

22 Apr 2013

Study: Image-guided brachytherapy prevents growth of cervical tumour in over 90% of patients

Two large, landmark radiotherapy studies have shown that it is possible to treat cervical cancer effectively with high doses specifically adapted to each tumour, and with fewer serious side-effects to the surrounding normal organs.

22 Apr 2013

Researchers suggest two days of staging at moderate altitude reduces acute mountain sickness

Afghanistan's geography is dominated by a collection of craggy peaks, the highest-a mountain known as Noshaq-has been measured to 7,492 meters. Consequently, the soldiers on duty in this mountainous terrain must often ascend to great heights as part of their duty.

22 Apr 2013

Advances in treatment have improved the chances of survival for young patients with cancer

Over the years, advances in treatment have improved the chances of survival for young patients with cancer. But long-term survivors need to be aware of cancer treatments that may place them at increased risk of heart disease later in life.

22 Apr 2013

Cerecor obtains exclusive, worldwide rights to NR2B receptor antagonist from Merck

Cerecor Inc, a neuroscience biotech company that develops therapies that have the potential to make a difference in diseases with high unmet medical needs, today announced that it has acquired exclusive, worldwide rights from Merck, known as MSD outside the United States and Canada, to develop and commercialize MK-0657, a small molecule NMDA receptor subunit 2B (NR2B) antagonist for all human indications, including depression.

22 Apr 2013

Advaxis completes ADXS-HPV Phase 1/2 dosing in patients with HPV-associated anal cancer

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that the first patient has been dosed in a Phase 1/2 study of ADXS-HPV in 25 patients with HPV-associated anal cancer coordinated by the Brown University Oncology Research Group (BrUOG).

22 Apr 2013

Advaxis to license its ADXS-HPV product candidate to FusionVax

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that it has entered into a Memorandum of Understanding (MoU) with FusionVax, Inc. ("FusionVax") setting forth the main terms under which Advaxis will, subject to the entry of a definitive agreement, exclusively license its lead clinical stage product candidate, ADXS-HPV, to FusionVax for Asia.

22 Apr 2013

Clinical Research Forum selects sickle cell project among 'Top 10' clinical research achievements of 2012

Pioneering research led by Johns Hopkins scientists on the use of partially matched bone marrow transplants to wipe out sickle cell disease has been selected as one of the Top 10 Clinical Research Achievements of 2012 by the Clinical Research Forum.

22 Apr 2013

Synta completes GALAXY-2 trial evaluating ganetespib inhibitor in non-small cell lung cance

Synta Pharmaceuticals Corp. announced today that the first patients have been treated in the randomized GALAXY-2 Phase 3 trial designed to evaluate docetaxel plus ganetespib, its investigational Hsp90 inhibitor, versus docetaxel alone for the second-line treatment of non-small cell lung adenocarcinoma.

22 Apr 2013

Janssen Diabetes Forum: A medical education initiative for management of type 2 diabetes

Launched today in Beerse, the Janssen Diabetes Forum (www.janssendiabetesforum.com) is a novel medical education initiative, which has been developed to contribute to the understanding of the latest developments in the management of type 2 diabetes.

22 Apr 2013

Study indentifies unmet medical need for treatment of patients with chronic pain and dysphagia

Collegium Pharmaceutical, Inc., a specialty pharmaceutical company focused on the development of innovative treatments for chronic pain, today announced the completion of a research study, conducted with an independent market research firm, that identified a significant unmet medical need for improved treatments for patients with chronic pain and dysphagia/odynophagia. In clinical practice, dysphagia is most often defined as difficulty in swallowing and odynophagia is defined as pain upon swallowing.

22 Apr 2013

Investigator honored for advancing osteoporosis research and advocacy worldwide

Professor Socrates Papapoulos, a long standing member of the IOF Board and leading researcher at the Leiden University Medical Center, has been named the recipient of the prestigious Pierre Delmas Award.

22 Apr 2013

Phase 2 study of VX-661 and ivacaftor shows significant improvements in lung function among CF patients

Vertex Pharmaceuticals Incorporated today announced data from a Phase 2 study of VX-661 and ivacaftor that showed statistically significant improvements in lung function among adults with cystic fibrosis (CF) who have two copies (homozygous) of the most common mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, known as F508del.

22 Apr 2013

First Edition: April 22, 2013

Today's headlines include reports ranging from how state leaders are dealing with the consequences of rejecting the health law's Medicaid expansion to how pending immigration reform proposals could ease the nation's physician shortage.

22 Apr 2013

Advanced microscope reveals process where mutations lead to autism and other diseases

Using spinning disk microscopy on barely day-old zebra fish embryos, University of Oregon scientists have gained a new window on how synapse-building components move to worksites in the central nervous system.

22 Apr 2013

MEDIAN Technologies selected as imaging solutions provider in phase II NSCLC clinical trial

MEDIAN Technologies (ALMDT), a leading medical imaging software solutions developer and a service provider for image interpretation and management in oncology clinical trials, announced today it has been selected as the imaging solutions and services provider in a new phase II clinical trial on Non Small Cell Lung Cancer (NSCLC).

22 Apr 2013

Medical Condition News

UB researchers develop aniontransporters to trigger cancer cell apoptosis

Discovery reverses the prevailing model of how dividing cells monitor equal distribution of chromosomes

American College of Surgeons grants Outstanding Achievement Award to 79 accredited cancer programs

Two views are necessary in 3D breast screening to ensure cancer is optimally visualized

Single puncture technique safe and effective in intravascular ultrasound-guided inferior vena cava filter placement

Study: Image-guided brachytherapy prevents growth of cervical tumour in over 90% of patients

Researchers suggest two days of staging at moderate altitude reduces acute mountain sickness

Advances in treatment have improved the chances of survival for young patients with cancer

Cerecor obtains exclusive, worldwide rights to NR2B receptor antagonist from Merck

Advaxis completes ADXS-HPV Phase 1/2 dosing in patients with HPV-associated anal cancer

Advaxis to license its ADXS-HPV product candidate to FusionVax

Clinical Research Forum selects sickle cell project among 'Top 10' clinical research achievements of 2012

Synta completes GALAXY-2 trial evaluating ganetespib inhibitor in non-small cell lung cance

Janssen Diabetes Forum: A medical education initiative for management of type 2 diabetes

Study indentifies unmet medical need for treatment of patients with chronic pain and dysphagia

Investigator honored for advancing osteoporosis research and advocacy worldwide

Phase 2 study of VX-661 and ivacaftor shows significant improvements in lung function among CF patients

First Edition: April 22, 2013

Advanced microscope reveals process where mutations lead to autism and other diseases

MEDIAN Technologies selected as imaging solutions provider in phase II NSCLC clinical trial

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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