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Ancestry could simplify searches for harmful mutations

Explosive advancement in human genome sequencing opens new possibilities for identifying the genetic roots of certain diseases and finding cures. However, so many variations among individual genomes exist that identifying mutations responsible for a specific disease has in many cases proven an insurmountable challenge.

26 Oct 2012

mTor molecule plays a significant role in myeloid differentiation

University of Illinois cell and developmental Biology professor Fei Wang and colleagues have created a new technique to study how myeloids, a type of blood stem cell, become the white blood cells important for immune system defense against infections and tissue damage.

26 Oct 2012

Targeted deletion of major VEGF gene in mice induces vision loss

Millions of people with "wet" macular degeneration are prescribed a class of medication known as anti-VEGF drugs. But now scientists at The Scripps Research Institute (TSRI) have found that a drastic reduction of VEGF activity may do more harm than good.

26 Oct 2012

Medical practice evolves: Prescribing habits, doc-patient relationship, health law changes

A push to treat chronic pain and financial disincentives for treating addiction may pressure clinicians into prescribing opioids for patients who are already addicted, a researcher suggested.

26 Oct 2012

Zebrafish model can test unique individual genetic differences in humans

The zebrafish is a potential tool for testing one class of unique individual genetic differences found in humans, and may yield information helpful for the emerging field of personalized medicine, according to a team led by Penn State College of Medicine scientists. The differences, or mutations, in question create minor changes in amino acids -- the building blocks of DNA -- from person to person.

26 Oct 2012

GW SMHS to host health expo for people with intellectual and developmental disabilities

The George Washington University (GW) School of Medicine and Health Sciences' (SMHS) Doctoral Physical Therapy program and Physician Assistant program will be hosting a health and wellness expo for persons living with intellectual and developmental disabilities (ages 16 and up). Caregivers are encouraged to attend, as well.

26 Oct 2012

NHCS researchers develop human heart cell model of ARVC

Researchers at the National Heart Centre Singapore (NHCS) have successfully created a human heart cell model of arrhythmogenic right ventricular cardiomyopathy (ARVC), an inherited heart muscle disorder which puts one at high risk of developing life-threatening arrhythmias and sudden cardiac death.

26 Oct 2012

Human Gene Therapy articles describe two novel anti-tumor therapies

Targeted T-cells can seek out and destroy tumor cells that carry specific antigen markers. Two novel anti-tumor therapies that take advantage of this T-cell response are described in articles published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

26 Oct 2012

NewYork-Presbyterian/Columbia participates in Symplicity system trial for hypertension

Patients with hypertension whose blood pressure cannot be brought down to safe levels despite taking three or more medications may have some relief coming their way. An innovative, first-of-its-kind clinical trial for a device representing a dramatic shift in treatment approaches for the toughest-to-treat patients is currently being conducted at NewYork-Presbyterian Hospital.

From Medtronic 26 Oct 2012

Highlights from 25th European College of Neuropsychopharmacology Congress

In the course of the 25th ECNP Congress leading experts and five and a half thousand psychiatrists, neurologists, neuroscience researchers and public health professionals from over 90 different countries met from 13 to 17 October 2012 in Vienna, Austria, to celebrate ECNP´s 25-year anniversary and engage in groundbreaking debate.

26 Oct 2012

CTCtrap can capture circulating tumour cells in cancer patients

The 7.5 millilitres of blood contained in a standard sample tube is not nearly enough to detect circulating tumour cells (CTCs) in the blood of patients with metastatic breast cancer, prostate cancer, or colorectal cancer with a high enough degree of reliability. These CTCs are the cause of metastases in cancer patients. If they can be effectively characterized, it is possible to arrive at a prognosis and to determine the most effective course of treatment.

26 Oct 2012

PFO closure with investigational device may prevent cryptogenic ischemic stroke

A clinical trial indicates that using an investigational medical device to close a PFO, or "hole in the heart," may be superior to medical management alone in the prevention of a repeated stroke.

26 Oct 2012

ACS BSCN accredits UCSD Bariatric Metabolic Institute as Level 1 facility

The Bariatric Metabolic Institute (BMI) at University of California, San Diego Health System has been accredited as a Level 1 facility by the Bariatric Surgery Center Network (BSCN) Accreditation Program of the American College of Surgeons (ACS). This designation means that the institutional performance of UC San Diego BMI meets the rigorous requirements outlined by the ACS BSCN Accreditation Program.

26 Oct 2012

Study defines complexity of underlying mutations responsible for pancreatic cancers

A large-scale study that defines the complexity of underlying mutations responsible for pancreatic cancers in more than 100 patients was published in Nature today.

26 Oct 2012

Study identifies essential mechanism that regulates calcium flow into mitochondria

Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell's energy storehouse - the mitochondria -- is important for understanding a cell's normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.

26 Oct 2012

New study offers hope for lonely older adults at increased risk of health problems

Always look on the bright side of life. Thanks to a new study from Concordia University, this catchy refrain offers a prescription for staying healthy during one's golden years.

26 Oct 2012

Extended exercises may improve people’s satisfaction with life

Had a bad day? Extending your normal exercise routine by a few minutes may be the solution, according to Penn State researchers, who found that people's satisfaction with life was higher on days when they exercised more than usual.

26 Oct 2012

UWCCC enrolls first patient in Phase 1-2 PET imaging trial of LIGHT for solid tumors

Novelos Therapeutics, Inc., a pharmaceutical company developing novel drugs for the treatment and diagnosis of cancer, today announced that the University of Wisconsin Carbone Cancer Center, a leading oncology research institution, has enrolled the first patient in a Phase 1-2 positron emission tomography (PET) imaging trial of I-124-CLR1404, a cancer-targeted PET imaging agent, in patients with nine solid tumor types, including triple negative breast, soft tissue sarcoma, colorectal, gastric, esophageal, prostate, ovarian, pancreatic and head & neck cancer.

26 Oct 2012

Jefferson researchers to investigate mechanisms involved in nephrogenic systemic fibrosis

Researchers at the Jefferson Institute of Molecular Medicine were awarded almost $384,000 by the National Institutes of Health to investigate the mechanisms involved in the development of a serious and sometimes fatal disease, known as Nephrogenic Systemic Fibrosis, a rare skin disorder linked to Gadolinium-based contrast agents used in magnetic resonance (MRI and MRA) studies.

26 Oct 2012

HCFC1 protein may cause intellectual disability

Genetics researchers at the University of Adelaide have solved a 40-year mystery for a family beset by a rare intellectual disability - and they've discovered something new about the causes of intellectual disability in the process.

26 Oct 2012

Medical Condition News

Ancestry could simplify searches for harmful mutations

mTor molecule plays a significant role in myeloid differentiation

Targeted deletion of major VEGF gene in mice induces vision loss

Medical practice evolves: Prescribing habits, doc-patient relationship, health law changes

Zebrafish model can test unique individual genetic differences in humans

GW SMHS to host health expo for people with intellectual and developmental disabilities

NHCS researchers develop human heart cell model of ARVC

Human Gene Therapy articles describe two novel anti-tumor therapies

NewYork-Presbyterian/Columbia participates in Symplicity system trial for hypertension

Highlights from 25th European College of Neuropsychopharmacology Congress

CTCtrap can capture circulating tumour cells in cancer patients

PFO closure with investigational device may prevent cryptogenic ischemic stroke

ACS BSCN accredits UCSD Bariatric Metabolic Institute as Level 1 facility

Study defines complexity of underlying mutations responsible for pancreatic cancers

Study identifies essential mechanism that regulates calcium flow into mitochondria

New study offers hope for lonely older adults at increased risk of health problems

Extended exercises may improve people’s satisfaction with life

UWCCC enrolls first patient in Phase 1-2 PET imaging trial of LIGHT for solid tumors

Jefferson researchers to investigate mechanisms involved in nephrogenic systemic fibrosis

HCFC1 protein may cause intellectual disability

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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