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Inovio's SynCon DNA vaccine effective at inducing CD8+ T cell responses specific to CMV

Inovio Pharmaceuticals, Inc. announced today that testing of multiple synthetic vaccine constructs for cytomegalovirus (CMV) induced robust T cells in mice, demonstrating the potential for a SynCon DNA vaccine to treat this virus that causes infant death and congenital abnormalities, is associated with cerebral palsy and brain tumors, and is the most common viral infection in organ transplant recipients. CMV is also associated with numerous inflammatory diseases and cancers, and is implicated in hypertension, a major risk factor for cardiovascular diseases.

26 Nov 2012

Negative messages not having an impact in people with addictive behaviors

What types of public messages will most likely deter drug and alcohol abuse or dissuade people from engaging in risky behavior? Negatively framed messages may not be an effective way to reach those most in need of persuasion, suggests a new study in Psychology of Addictive Behaviors by researchers from Indiana University and Wayne State University.

26 Nov 2012

AMITIZA for treatment of chronic constipation now available in Japan

Sucampo Pharmaceuticals, Inc. and Abbott today announced the availability of AMITIZA (lubiprostone) in Japan, a prescription medicine for the treatment of chronic constipation not caused by organic diseases. AMITIZA was approved by the Ministry of Health, Labor and Welfare (MHLW) in Japan in June.

26 Nov 2012

Cancer-killing viruses found safe but less effective than expected

Doctors now use cancer-killing viruses to treat some patients with lethal, fast-growing brain tumors. Clinical trials show that these therapeutic viruses are safe but less effective than expected.

26 Nov 2012

Mental activities like reading and writing can preserve structural integrity in the brains of older people

Mental activities like reading and writing can preserve structural integrity in the brains of older people, according to a new study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Weight loss and quality of sleep: an interview with Kerry Stewart

In our particular study we used a survey which consisted of 50 different questions which get at different aspects of sleep health. It was a patient self-report.

26 Nov 2012

Researchers reveal molecular mechanisms that lead to basal cell carcinoma initiation

Advanced online publication in Nature Cell Biology: Researchers at the Université libre de Bruxelles, uncover the molecular mechanisms leading to basal cell carcinoma initiation.

26 Nov 2012

Study confirms high biocompatibility of polymeric materials with brain tissue

Professor José Miguel Soria, a member of the Institute of Biomedical Sciences, Universidad CEU Cardenal Herrera, has co-directed with Professor Manuel Monleón of the Universitat Politècnica de València a study on the compatibility of polymeric biomaterials in the brain and its effectiveness to favour neuroregeneration in areas with some kind of damage or brain injury.

26 Nov 2012

Stroke patients may perform better in clinical tests when offered a reward

Stroke patients who have difficulty paying attention to part of their visual field may perform better when offered a reward, a study by Imperial College London and Brunel University researchers has found.

26 Nov 2012

Both very high and low physical activity levels associated with knee cartilage degeneration

Both very high and very low levels of physical activity can accelerate the degeneration of knee cartilage in middle-aged adults, according to a new study presented at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Apitope announces completion of recruitment in ATX-MS-1467 Phase I trial for MS

Apitope, the European drug discovery and development company focused on treating the underlying cause of autoimmune diseases, today announced completion of recruitment into its second Phase I clinical trial of ATX-MS-1467 in patients with multiple sclerosis (MS).

26 Nov 2012

$Study identifies fractional anisotropy as predictor of brain damage after TBI$

Study identifies fractional anisotropy as predictor of brain damage after TBI

Using a special magnetic resonance imaging (MRI) technique to image patients with mild traumatic brain injury (MTBI), researchers have identified a biomarker that may predict which patients will do well over the long term, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Study examines pediatric injuries associated with inflatable bouncers

A new study by researchers at the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital examined pediatric injuries associated with inflatable bouncers, such as bounce houses and moonwalks.

26 Nov 2012

People with Parkinson's benefit from exercise programs on stationary bicycles

People with Parkinson's disease benefit from exercise programs on stationary bicycles, with the greatest effect for those who pedal faster, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Active lifestyle helps preserve brain structure and could reduce burden of dementia, Alzheimer's

An active lifestyle helps preserve gray matter in the brains of older adults and could reduce the burden of dementia and Alzheimer's disease (AD), according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Study shows how MCUR1 protein helps regulate movement of calcium into mitochondria

A team of scientists from Temple University School of Medicine and the University of Pennsylvania has moved another step closer to solving a decades-long mystery of how the all-important flow of calcium into the cell's power source, the mitochondria, is controlled.

26 Nov 2012

iCAD introduces VersaVue Enterprise 3.2.1 MR software

iCAD, Inc., an industry-leading provider of advanced image analysis, workflow solutions and radiation therapy for the identification and treatment of cancer, announced today it will launch VersaVue Enterprise 3.2.1, the latest release of the company's MR software solution that provides improvements in workflow efficiency and flexibility, at the annual conference of the Radiological Society of North America (RSNA) taking place in Chicago, November 25-30.

26 Nov 2012

Turning off particular cytokines reduces Alzheimer's typical amyloid-- deposits in mice

Alzheimer's disease is one of the most common causes of dementia. In Germany and Switzerland alone, around 1.5 million people are affected, and forecasts predict a doubling of the number of patients worldwide within the next 20 years. The accumulation of particular abnormal proteins, including amyloid-- (Aβ) among others, in patients' brains plays a central role in this disease.

26 Nov 2012

Fear of movement affects 20% of patients with coronary artery disease

A doctoral thesis at Sahlgrenska Academy, University of Gothenburg, Sweden, has found that one out of five patients with coronary artery disease experience such a great fear of movement (kinesiophobia) that their health may suffer as a result.

23 Nov 2012

New way of long-term care for elders with memory impairments

Within a stone's throw from the hustle and bustle of Route 128, a revolutionary new way to provide elder care is quietly making a difference in the town of Westwood. From the outside, the White Oak Cottages may look like ordinary, modern family homes with lots of windows and skylights but what's going on inside is anything but ordinary. Their mission is to de-institutionalize long-term care by providing a real home-like environment for those with Alzheimer's, Dementia and other cognitive impairments.

23 Nov 2012