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New, more effective DBS paradigm may manage Parkinson's symptoms

Parkinson's disease (PD) is a devastating and incurable disease that causes abnormal poverty of movement, involuntary tremor, and lack of coordination. A technique called deep brain stimulation (DBS) is sometimes used to improve motor symptoms in patients with advanced disease. Now, a study published by Cell Press in the October 20 issue of the journal Neuron describes a new and more effective DBS paradigm that makes real-time adjustments in response to disease dynamics and progression and may be better for managing symptoms of advanced PD.

20 Oct 2011

Link between neighborhood poverty and low-income women's health

Low-income women with children who move from high-poverty to lower-poverty neighborhoods experience notable long-term improvements in some aspects of their health, namely reductions in diabetes and extreme obesity, according to a new study by researchers at the University of Chicago and partner institutions.

20 Oct 2011

Advances in yttrium-90 radioembolization for liver cancer

Finding innovative, minimally invasive ways to treat liver cancer-and being able to tailor that treatment individually to patients-are hallmarks of interventional radiologists. Advances in yttrium-90 (Y-90) radioembolization for liver cancer, a leading cause of cancer deaths worldwide, are reported in studies in the October Journal of Vascular and Interventional Radiology.

20 Oct 2011

'Lance Armstrong effect' could become powerful new cancer weapon

The "Lance Armstrong effect" could become a powerful new weapon to fight cancer cells that develop resistance to chemotherapy, radiation and other treatments, scientists say in a report in the ACS journal Molecular Pharmaceutics.

20 Oct 2011

JHU, Eisai enter drug-discovery research collaboration for brain disorders

The Johns Hopkins University (JHU) has entered into a drug-discovery research collaboration with Eisai, a pharmaceutical company based in Tokyo, to develop proprietary small-molecule drugs for a range of brain conditions such as schizophrenia, pain, brain tumors and Alzheimer's disease.

20 Oct 2011

EMA, FDA endorse use of biomarkers in Alzheimer's drug trials

A news feature in Alzforum explains the impact of new guidelines for selecting volunteers in clinical trials of Alzheimer's drugs. The European Medicines Agency (EMA), the European counterpart to the U.S. Food and Drug Administration (FDA), has endorsed the use of biomarkers—substances in the body or measurements that serve as indicators of disease—to select patients to be included in drug trials.

20 Oct 2011

Winter health and safety tips

Winter is a special time for celebration. It should also be a time for added caution if you or someone in your family is an older adult. It is the season for falls, slips on icy streets, and other dangers that can be especially harmful for older adults. "Something as simple as a fall can be devastating for older men and women," says Dr. Evelyn Granieri, director of the Division of Geriatrics at NewYork-Presbyterian Hospital/The Allen Hospital. "Before the cold weather arrives, it is important to prepare."

20 Oct 2011

CJC publishes paper on safety of cardiac imaging methods

Canadian Journal of Cardiology has published a paper on the safety of cardiac imaging methods. This study is important for patients worried about radiation exposure during X-ray based studies of the heart. X-ray based methods have greatly improved the diagnosis of heart disease, but they can produce significant levels of radiation exposure.

20 Oct 2011

BUSM, COE receive NIH training grant to examine inflammatory disorders

The National Institutes of Health (NIH) has awarded Boston University School of Medicine (BUSM) and the College of Engineering (COE) a five year, $316,875 training grant to examine inflammatory disorders.

20 Oct 2011

CJC publishes paper on the timing of coronary stenting

The Canadian Journal of Cardiology has published a paper on the timing of coronary stenting, a thought-provoking paper that challenges one of the dogmas of acute heart attack management today.

20 Oct 2011

RCSI study: Alpha-1 antitrypsin deficiency more prevalent in Ireland

Researchers from the Royal College of Surgeons in Ireland (RCSI), Beaumont Hospital, and Trinity College Dublin have conducted a study which has found that Ireland has one of the highest incidences in the world of a genetic condition that causes severe hereditary emphysema.

20 Oct 2011

IOF's 1st Middle-East and Africa Osteoporosis Meeting to be held in Dubai

Doctors and clinical investigators from the throughout the Middle East gathered today in Dubai for the opening of the International Osteoporosis Foundation's (IOF) 1st Middle-East and Africa Osteoporosis Meeting.

20 Oct 2011

Common link between Type 2 diabetes and autism

A review of the genetic and biochemical abnormalities associated with autism reveals a possible link between the widely diagnosed neurological disorder and Type 2 diabetes, another medical disorder on the rise in recent decades.

20 Oct 2011

AAN updated guideline on how to best treat essential tremor

The American Academy of Neurology is releasing an updated guideline on how to best treat essential tremor, which is the most common type of tremor disorder and is often confused with other movement disorders such as Parkinson's disease.

20 Oct 2011

Pesticides, pollutants increase risk of spina bifida and anencephaly in rural China

Pesticides and pollutants are related to an alarming 450 percent increase in the risk of spina bifida and anencephaly in rural China, according to scientists at The University of Texas at Austin and Peking University.

20 Oct 2011

BUSM to develop novel technologies for early lung cancer detection

Boston University School of Medicine (BUSM) is the lead institution on a $13.6 million study aimed at developing novel technologies for the early detection of lung cancer.

20 Oct 2011

UofL, Frazier Rehab to establish Spinal Cord Injury Model System

The National Institute on Disability and Rehabilitation Research (NIDRR) of the U.S. Department of Education has awarded researchers at Frazier Rehab Institute and the University of Louisville $2.2 million for five years to establish a Spinal Cord Injury Model System.

20 Oct 2011

People with Parkinson's can benefit from computer-based physical therapy games

Playing computer-based physical therapy games can help people with Parkinson's disease improve their gait and balance, according to a new pilot study led by the UCSF School of Nursing and Red Hill Studios, a California serious games developer.

20 Oct 2011

Data from Concert Pharmaceuticals' CTP-499 study to be presented at ASN Kidney Week 2011

Concert Pharmaceuticals, Inc. today announced that three abstracts relating to CTP-499, its clinical candidate for the potential treatment of diabetic nephropathy, have been accepted for poster presentations at the American Society of Nephrology's (ASN) Kidney Week 2011.

19 Oct 2011

Comprehensive roadmap promises to improve cancer immunotherapy development

The Cancer Immunotherapy Consortium (CIC) of the Cancer Research Institute (CRI) and the Association for Cancer Immunotherapy (CIMT) have issued a joint white paper, published in the October 13 issue of Nature Biotechnology, outlining a comprehensive roadmap that promises to help improve and facilitate the path forward in the development of novel immunotherapies for cancer.

19 Oct 2011