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BUSM leads genome-wide evaluation of genetic variants associated with Parkinson's disease

Boston University School of Medicine investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease (PD). The study, which is published online in PLOS ONE, points to the involvement of specific genes and alterations in their expression as influencing the risk for developing PD.

6 Oct 2012

Benzodiazepine exposure for over-65s linked to increased risk of dementia

The results from comparative analysis of this population demonstrate the risk of developing dementia increased by 50% for subjects who consumed benzodiazepines during the follow-up period, compared with those who had never used benzodiazepines.

6 Oct 2012

Researchers discover brain mechanism responsible for sensation of nausea

Nausea is a common and distressing side effect of many drugs and treatments. Unlike vomiting, nausea is not well understood, but new research by University of Guelph scientists may soon change that.

6 Oct 2012

Two genes linked to increased risk of diabetes-associated kidney disease

An international group of researchers has discovered two genes that increase the risk of developing diabetes-associated kidney disease.

6 Oct 2012

Public health significance and societal consequences of pathological gambling

The panel discussion on the occasion of the 25th ECNP Congress in Vienna, Austria, will focus not only on medical issues of pathological gambling, but also on its public health significance and societal consequences.

6 Oct 2012

RXi receives SBIR grant to enable discovery and preclinical development of sd-rxRNAs

RXi Pharmaceuticals Corporation, a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced that it was awarded a Small Business Innovation Research (SBIR) grant by the National Cancer Institute (NCI) of the National Institutes of Health (NIH).

5 Oct 2012

MannKind completes enrollment in AFREZZA Phase 3 clinical studies for type 1 and 2 diabetes

MannKind Corporation today announced that it has completed recruiting patients for two Phase 3 clinical studies of AFREZZA (insulin human [rDNA origin]), an investigational, ultra rapid-acting mealtime insulin therapy, administered using MannKind's to-be-marketed next-generation inhaler.

5 Oct 2012

Home hemodialysis more accessible than ever

Most patients with chronic kidney disease who undergo hemodialysis put up with a grueling treatment regimen that involves going into a clinic several days a week and sitting through a three-to-four hour dialysis session at each visit. Home hemodialysis is more accessible than ever, though, with the advent of newer systems that are easier for patients to learn, use, and maintain, according to a review appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

5 Oct 2012

UCLA project to promote healthy nutrition and physical activity to curb obesity

Researchers at the UCLA Fielding School of Public Health and UCLA's Jonsson Comprehensive Cancer Center have been awarded a $20 million federal grant to further their innovative efforts to curb obesity, a global pandemic that has reached the level of a national crisis in the United States.

5 Oct 2012

Paper proposes novel mathematical models for injection of insulin in type 1 and 2 diabetes

Diabetes mellitus is a chronic disease in which individuals exhibit high levels of sugar in the blood, either due to insufficient production of insulin-the hormone that allows glucose to be absorbed by body cells-or the body's lack of response to insulin. Type 1 diabetes occurs due to loss or dysfunction of β-cells of the pancreas, the organ that produces insulin. Type 2 diabetes is caused by a defective glucose-insulin regulatory system.

5 Oct 2012

Type 2 diabetes screening does not appear to affect mortality rates

Screening for type 2 diabetes does not appear to affect overall population mortality rates, according to a new study published in The Lancet.

5 Oct 2012

UT Austin chair to receive Founders Award from National Academy of Engineering

The National Academy of Engineering has selected Nicholas Peppas as its 2012 Founders Award recipient in recognition of his pioneering work in the areas of polymer chemistry, bioengineering, pharmaceutical sciences and advanced drug delivery.

5 Oct 2012

The New York Times articles address harsh realities of what happens when addiction hits home

In Tuesday's health section of The New York Times, "When a Drug Addict Isn't Ready to Accept Help" and "In Business, Nondrinking Can Be a Costly Expense," both articles address the harsh realities of what happens when addiction hits home.

5 Oct 2012

Researchers determine function of new IKKα enzyme variant in colorectal cancer

Researchers from IMIM, Hospital del Mar Medical Research Institute, have succeeded in determining the function of a new variant of enzyme IKKalpha (IKKα) to activate some of the genes taking part in the tumor progressions of colorectal cancer.

5 Oct 2012

Study links PI3Kgamma molecule with multiple sclerosis

A University of Adelaide researcher has published results that suggest a possible new mechanism to control multiple sclerosis (MS).

5 Oct 2012

People with difficulty in chewing foods more likely to develop dementia

Can you bite into an apple? If so, you are more likely to maintain mental abilities, according to new research from Karolinska Institutet in Sweden.

5 Oct 2012

QRS prolongation associated with increased rates of heart-failure mortality

A new study from Karolinska Institutet in Sweden demonstrates that a change in the ECG wave called the QRS prolongation is associated with a higher rate of heart-failure mortality.

5 Oct 2012

Blood clot-busting enzymes much busier than previously imagined

The body's blood clot-busting enzymes are much busier than previously imagined, with new research showing that they also dispose of every cell that dies prematurely from disease or trauma.

5 Oct 2012

Myocardial infarction mortality rates decrease by 44% over the last 15 years in Argentina

Mortality caused by myocardial infarction has decreased by 44% over the last 15 years in Argentina, according to new research which will be presented during the 38th Argentine Congress of Cardiology.

5 Oct 2012

Urgent action needed to improve outcomes for lung cancer patients, says expert

Urgent action is needed to improve outcomes for lung cancer patients, a leading lung cancer expert will explain in a public lecture at the University of Leicester.

5 Oct 2012