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Infinity announces new data from IPI-145 Phase 1 trial on advanced hematologic malignancies

Infinity Pharmaceuticals, Inc. today announced new data from its ongoing Phase 1, open-label, dose-escalation trial of IPI-145, the company's potent, oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma, in patients with advanced hematologic malignancies.

11 Dec 2012

Alpha arrestins may play a role in cell signaling that is crucial to new drug development

A newly found understanding of receptor signaling may have revealed a better way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a role in cell signaling that is crucial to new drug development.

11 Dec 2012

Boston College professor to research into new drugs that can prevent onset of toxoplasmosis

The American Cancer Society has awarded a four-year, $720,000 grant to Boston College Associate Professor of Biology Marc-Jan Gubbels for research into potential new drugs that can prevent the onset of toxoplasmosis in cancer patients with weakened immune systems.

10 Dec 2012

Boehringer Ingelheim to commence volasertib plus LDAC Phase III study for AML

New positive Phase II results from an interim analysis of the randomised Phase I/II study involving the company's investigational haematology/oncology compound volasertib in newly diagnosed patients with acute myeloid leukemia (AML) considered ineligible for intensive remission induction therapy were presented at the 54th American Society of Hematology (ASH) annual meeting in Atlanta, USA.

10 Dec 2012

Strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality

A new American Cancer Society study finds a strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality. The authors say people who drank more than four cups of caffeinated coffee per day were at about half the risk of death of these often fatal cancers compared to those who only occasionally or who never drank coffee.

10 Dec 2012

Patients with sickle cell disease rely more on emergency room

Patients with sickle cell disease rely more on the emergency room as they move from pediatric to adult health care, according to researchers at Washington University School of Medicine in St. Louis.

10 Dec 2012

Potential way to attack common stomach bacteria that cause ulcers

Experiments at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have revealed a potential new way to attack common stomach bacteria that cause ulcers and significantly increase the odds of developing stomach cancer.

10 Dec 2012

Tips to prevent ‘holiday heart’ syndrome

The holiday season is supposed to be joyous, fun and happy. But it can also be stressful. The nation's emergency physicians want to remind all Americans to keep your stress in check.

10 Dec 2012

Pfizer joins WIN Consortium to improve personalized cancer care

Worldwide Innovative Network (WIN) in personalized cancer medicine consortium today proudly announced that Pfizer, Inc (NYSE:PFE) is the first pharmaceutical company to become a member of the consortium. Founded on the recognition that greater success can be achieved through collaboration than any organization can achieve alone, the WIN Consortium is a global network of leading academic, industry, and patient advocacy organizations working to make personalized cancer care a reality for patients worldwide.

10 Dec 2012

Giving iron supplements to low birth weight infants reduces behavior problems later in life

In a study published today in Pediatrics, scientists at Umeå University in Sweden conclude that giving iron supplements to low birth weight infants reduces the risk of behavior problems like ADHD later in life.

10 Dec 2012

New study could help develop anti-inflammatory drugs with fewer side effects

10 Dec 2012

Ex-con gets arrested on purpose in order to get health care

A 56-year-old ex-convict says he purposely got arrested for shoplifting to get prison health care for his leukemia.

10 Dec 2012

New assay test shows positive results for patients with recurrent or metastatic breast cancer

When breast cancer advances, the patient doesn't have the luxury of time. Finding the right type of chemotherapy as quickly as possible is a critical factor for the patient's success and, until now, predicting the patient's sensitivity to chemotherapy has often been a shot in the dark.

10 Dec 2012

JPND invites proposals from researchers to understand the underlying causes of neurodegenerative diseases

The EU Joint Programme - Neurodegenerative Disease Research (JPND) is inviting calls for proposals from research teams across Europe to increase understanding of the factors that put people at risk of developing neurodegenerative diseases (ND) such as Alzheimer's and also to evaluate health and social care strategies for people living with these debilitating illnesses.

10 Dec 2012

New hope for leukemia patients

Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients' tumors responded to the therapy, which was pioneered by scientists in the Perelman School of Medicine at the University of Pennsylvania

10 Dec 2012

Surgical patients with chronic psychological symptoms require psychotherapeutic treatment

In their study, the research group, headed by Privatdozent Dr. Henning Krampe, psychologist at the Charité Department of Anesthesiology and Intensive Care Medicine, Prof. Claudia Spies, Director of the Charité Department of Anesthesiology and Intensive Care Medicine and Prof. Elmar Brähler, Head of the Department of Medical Psychology and Medical Sociology at the University of Leipzig, initially recorded how many patients faced by a forthcoming operation were interested in psychotherapy sessions and to what extent this interest was associated with the increased psychological distress occurring before the operation. Finally, the scientists examined whether changes in the psychological symptoms took place during the six months following the surgery.

10 Dec 2012

Cervical disc replacement: an interview with Joe Ross, VP of U.S. Marketing at LDR

Cervical disc replacement is a surgical procedure that involves removing a damaged or degenerated cervical disc and replacing it with an artificial disc device.

10 Dec 2012

Physician's Technology launches WilloMD iLaserX device

The Italian Renaissance sculptor Michelangelo once declared "everything hurts". Baby boomers are more active than ever and stress their joints. Millions rely on dangerous pain meds and injections to stay active. Pain medication and injections can be dangerous and even lethal. Popular therapeutic pain laser technology offers hope but is not practical for home use and is out of reach of a vast patient population.

10 Dec 2012

Vorinostat reduces risk of graft-vs.-host disease from bone marrow transplant treatments

A new class of drugs reduced the risk of patients contracting a serious and often deadly side effect of lifesaving bone marrow transplant treatments, according to a study from researchers at the University of Michigan Comprehensive Cancer Center.

10 Dec 2012

Ipsen, Active Biotech complete enrollment in tasquinimod Phase III trial for prostate cancer

Active Biotech and Ipsen today announced that the Phase III clinical trial for tasquinimod, a novel compound for the treatment of prostate cancer, is successfully enrolled with over 1,200 randomized patients as planned in the clinical protocol.

10 Dec 2012

Medical Condition News

Infinity announces new data from IPI-145 Phase 1 trial on advanced hematologic malignancies

Alpha arrestins may play a role in cell signaling that is crucial to new drug development

Boston College professor to research into new drugs that can prevent onset of toxoplasmosis

Boehringer Ingelheim to commence volasertib plus LDAC Phase III study for AML

Strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality

Patients with sickle cell disease rely more on emergency room

Potential way to attack common stomach bacteria that cause ulcers

Tips to prevent ‘holiday heart’ syndrome

Pfizer joins WIN Consortium to improve personalized cancer care

Giving iron supplements to low birth weight infants reduces behavior problems later in life

New study could help develop anti-inflammatory drugs with fewer side effects

Ex-con gets arrested on purpose in order to get health care

New assay test shows positive results for patients with recurrent or metastatic breast cancer

JPND invites proposals from researchers to understand the underlying causes of neurodegenerative diseases

New hope for leukemia patients

Surgical patients with chronic psychological symptoms require psychotherapeutic treatment

Cervical disc replacement: an interview with Joe Ross, VP of U.S. Marketing at LDR

Physician's Technology launches WilloMD iLaserX device

Vorinostat reduces risk of graft-vs.-host disease from bone marrow transplant treatments

Ipsen, Active Biotech complete enrollment in tasquinimod Phase III trial for prostate cancer

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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