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New survival results from Genentech’s Perjeta Phase III combination study on HER2-positive mBC

Genentech, a member of the Roche Group, today announced updated survival results from the Phase III CLEOPATRA study, which showed that the combination of Perjeta (pertuzumab), Herceptin (trastuzumab) and docetaxel chemotherapy significantly extended the lives (overall survival) of people with previously untreated HER2-positive metastatic breast cancer (mBC), compared to Herceptin, chemotherapy and placebo.

10 Dec 2012

Study examines association between ischemic-hypoxic conditions and ADHD

Children who had in-utero exposure to ischemic-hypoxic conditions, situations during which the brain is deprived of oxygen, were significantly more likely to develop attention deficit hyperactivity disorder later in life as compared to unexposed children, according to a Kaiser Permanente study published in the journal Pediatrics.

10 Dec 2012

Ibrutinib may effectively combat chronic lymphocytic leukemia

The promising investigational targeted therapy ibrutinib and its mechanism of silencing gene communication pathways critical to the development of cancer may be an effective way to combat chronic lymphocytic leukemia (CLL), according to studies presented today at the 54th Annual Meeting of the American Society of Hematology (ASH).

10 Dec 2012

MSKCC establishes new pancreatic cancer research center

A new pancreatic cancer research center has been created at Memorial Sloan-Kettering Cancer Center (MSKCC). The ambitious initiative was established with an initial commitment of $10 million from MSKCC Board member David M. Rubenstein.

10 Dec 2012

Genzyme receives EC approval for Thyrogen product label expansion

Genzyme, a Sanofi company, today announced it has received European Commission approval of a product label expansion for the use of Thyrogen (thyrotropin alfa) with a wider irradiation dose range for postoperative thyroid remnant ablation.

10 Dec 2012

Angiocidin reduces acute myeloid leukemia cells in vivo by almost two-thirds in pre-clinical studies

Angiocidin, a novel tumor-inhibiting protein, has been shown to reduce acute myeloid leukemia (AML) cells in vivo by almost two-thirds in pre-clinical experiments.

10 Dec 2012

Maintaining weight loss may improve cardiometabolic profile in postmenopausal women

When you're postmenopausal and overweight, losing weight is a good thing, but gaining back just a few pounds may actually be detrimental to your cardiovascular health.

10 Dec 2012

BlueGenics aims to discover new drugs from deep sea to combat osteoporosis

Searching for substances from the deep sea to combat osteoporosis and other human common diseases is one of the objectives of the new European research project "BlueGenics" which has received funding of EUR 6 million from the European Commission.

10 Dec 2012

Mesupron could extend progression-free survival for metastatic breast cancer patients

Previous research has shown that a family of genes, proteins and enzymes called the uPA system (for urokinase plasminogen activator) plays an active role in different facets of cancer's biology, including tumor cell invasion, the spread of metastases, and the growth of a primary tumor. Mesupron- is a new small molecule inhibitor, taken as a pill, that inhibits the uPA system.

10 Dec 2012

Sinai Hospital of Baltimore announces opening of new geriatric surgery center

Sinai Hospital of Baltimore, a LifeBridge Health center, is proud to announce the opening of the Sinai Center for Geriatric Surgery, the nation's first surgical center dedicated exclusively to providing specialized surgical and pre and postoperative care for elderly patients.

10 Dec 2012

Sanofi announces new data from SAR302503 Phase II trial on myelofibrosis

Sanofi announced today new Phase II data showing that treatment with a novel, investigational, selective JAK2 inhibitor (SAR302503) reduced spleen size and improved constitutional symptoms in patients with intermediate-2 or high-risk primary or secondary myelofibrosis (MF), a hematologic malignancy with unmet medical needs.

10 Dec 2012

Delirium associated with higher mortality rates

A new meta-analysis has found that delirium, a condition developed by many patients in hospital intensive care units (ICU), is associated with higher mortality rates, more complications, longer stays in the ICU, and longer hospitalizations.

10 Dec 2012

Iroko’s submicron indomethacin Phase 3 study on post-surgical acute pain meets primary endpoint

Iroko Pharmaceuticals, LLC today announced that the Phase 3 study evaluating the company's investigational, lower dose submicron indomethacin in post-surgical acute pain met its primary endpoint of demonstrating significant pain relief compared with placebo.

10 Dec 2012

New 3D culture system mimics environment surrounding inflammatory breast cancer cells

Inflammatory breast cancer (IBC) is a very rare and aggressive disease that progresses rapidly and is associated with a very low survival rate. To understand how this type of cancer spreads, it's crucial to characterize the interactions between cancer cells and their 3D environment.

10 Dec 2012

Brazil Scientific Motility Society awards training grant to GHSU’s Department of Physiology

The Department of Physiology at the Medical College of Georgia at Georgia Health Sciences University has been awarded a training grant from the Brazil Scientific Motility Society to advance the education of future scientists and scientific discovery.

10 Dec 2012

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant to treatment and may even accumulate additional genetic aberrations, eventually leading to disease progression and relapse. These leukemia stem cells are full of genetic errors, loaded with potentially lethal breaks in DNA, and are in a state of constant self-repair.

10 Dec 2012

FoxP3 gene expression identifies ALS disease progression in 80% of patients

The debilitating symptoms of amyotrophic lateral sclerosis, or ALS, appear to be increased by a lack of inflammation-reducing T cells, report scientists from the Methodist Neurological Institute in an upcoming print issue of The EMBO Molecular Medicine Journal.

10 Dec 2012

Beth Israel Deaconess Medical Center introduces CeliacNow website

It's estimated that one in 100 people in the United States are living with celiac disease, but there are only a handful of celiac centers throughout the country. In response to a growing need for educational materials, clinicians at Beth Israel Deaconess Medical Center's Celiac Center have launched CeliacNow, a nutritional management website designed to maximize the health and wellbeing of people living with celiac disease and other gluten-related disorders.

10 Dec 2012

GSK, MD Anderson partner to develop new therapeutic antibodies against cancer

The University of Texas MD Anderson Cancer Center and GlaxoSmithKline (GSK) have signed a research collaboration and license agreement to develop new therapeutic antibodies that promote an immune system attack against cancer.

10 Dec 2012

American Journal of Psychiatry publishes results from Successful Aging Evaluation study

Presently, there are about 40 million Americans over the age of 65, with the fastest-growing segment of the population over 80 years old. Traditionally, aging has been viewed as a period of progressive decline in physical, cognitive and psychosocial functioning, and aging is viewed by many as the "number one public health problem" facing Americans today.

9 Dec 2012

Medical Condition News

New survival results from Genentech’s Perjeta Phase III combination study on HER2-positive mBC

Study examines association between ischemic-hypoxic conditions and ADHD

Ibrutinib may effectively combat chronic lymphocytic leukemia

MSKCC establishes new pancreatic cancer research center

Genzyme receives EC approval for Thyrogen product label expansion

Angiocidin reduces acute myeloid leukemia cells in vivo by almost two-thirds in pre-clinical studies

Maintaining weight loss may improve cardiometabolic profile in postmenopausal women

BlueGenics aims to discover new drugs from deep sea to combat osteoporosis

Mesupron could extend progression-free survival for metastatic breast cancer patients

Sinai Hospital of Baltimore announces opening of new geriatric surgery center

Sanofi announces new data from SAR302503 Phase II trial on myelofibrosis

Delirium associated with higher mortality rates

Iroko’s submicron indomethacin Phase 3 study on post-surgical acute pain meets primary endpoint

New 3D culture system mimics environment surrounding inflammatory breast cancer cells

Brazil Scientific Motility Society awards training grant to GHSU’s Department of Physiology

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

FoxP3 gene expression identifies ALS disease progression in 80% of patients

Beth Israel Deaconess Medical Center introduces CeliacNow website

GSK, MD Anderson partner to develop new therapeutic antibodies against cancer

American Journal of Psychiatry publishes results from Successful Aging Evaluation study

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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