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Study describes new compounds that inhibit PRMT1 enzyme

Scientists at The Scripps Research Institute have found the first chemical compounds that act to block an enzyme that has been linked to inflammatory conditions such as asthma and arthritis, as well as some inflammation-promoted cancers.

11 May 2012

New insights into how body's innate immunity is triggered to create effective immune response

Singapore scientists from Bioprocessing Technology Institute (BTI) under the Agency of Science, Technology and Research (A*STAR) have for the first time, identified the molecular 'switch' that directly triggers the body's first line of defence against pathogens, more accurately known as the body's "innate immunity".

11 May 2012

'Packing problem' could have a solution for cancer treatment

A hidden facet of a math problem that goes back to Sanskrit scrolls has just been exposed by nanotechnology researchers at the University of Michigan and the University of Connecticut.

11 May 2012

FDA advisory committee supports lorcaserin for weight management

Arena Pharmaceuticals, Inc. and Eisai Inc. announced today that the US Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee voted 18 to 4, with one abstention, that the available data demonstrate that the potential benefits of lorcaserin outweigh the potential risks when used long-term in a population of overweight and obese individuals.

11 May 2012

FDA warns about 'liberation therapy' for multiple sclerosis

The U.S. Food and Drug Administration is alerting health care professionals and patients about injuries and death associated with the use of an experimental procedure sometimes called "liberation therapy" or the "liberation procedure" to treat chronic cerebrospinal venous insufficiency (CCSVI).

11 May 2012

BioTrends tracks uptake of Yervoy and Zelboraf for advanced melanoma

BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, has released findings from the second wave of its LaunchTrends® Yervoy and Zelboraf report, in which 103 U.S.-based medical oncologists were surveyed about their current and expected treatment patterns in advanced melanoma.

11 May 2012

Threshold for when to choose surgery over medical therapy for recurrent acute rhinosinusitis

A study in the May 2012 issue of Otolaryngology-Head and Neck Surgery suggests a threshold for when to choose surgery over medical therapy for recurrent acute rhinosinusitis (RARS) based on the patients' lost productivity in response to RARS and each treatment strategy.

11 May 2012

Less invasive procedure for heart disease

Doctors at Regions Hospital have begun performing a less invasive procedure for heart disease. Transcatheter aortic valve replacement (TAVR) was approved last November by the U.S. Food and Drug Administration for elderly patients who are too frail or too old for open heart surgery. The device is not approved for patients who are eligible for open heart surgery.

11 May 2012

Mylan introduces Atorvastatin Calcium in France, Belgium, UK, Ireland and the Netherlands

Mylan Inc. today announced that it has launched Atorvastatin Calcium Tablets, 10 mg, 20 mg, 40 mg and 80 mg in France, Belgium, the UK, the Netherlands and Ireland.

11 May 2012

Positive results from Cytochroma CTAP101 Phase 2b clinical trial for CKD

Cytochroma today announced positive clinical trial results for its lead product, CTAP101 Capsules. In a recently completed Phase 2b trial, CTAP101 Capsules effectively and safely lowered elevated plasma intact parathyroid hormone (iPTH) in patients with Stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

11 May 2012

Study supports catheter ablation as first-line treatment for paroxysmal atrial fibrillation

Patients with the heart rhythm disorder atrial fibrillation (AFib) who received first-line catheter ablation treatment had a longer arrhythmia-free interval than patients receiving antiarrhythmic drugs, the standard first-line treatment.

11 May 2012

CTI receives EU conditional marketing authorization for Pixuvri to treat non-Hodgkin B-cell lymphomas

CellTherapeutics today announced that it has received conditional marketing authorization from the European Commission for Pixuvri (pixantrone) as monotherapy for the treatment of adult patients with multiply relapsed or refractory aggressive non-Hodgkin B-cell lymphomas. Pixuvri is the first approved treatment in the European Union in this patient setting.

11 May 2012

New discovery platform for antigen-specific monoclonal antibodies

Cell Signaling Technology, Inc. of Danvers, MA is pleased to announce the development of a new discovery platform for antigen-specific monoclonal antibodies.

From Cell Signaling Technology 11 May 2012

BIOTRONIK launches new Reocor external pacemaker

BIOTRONIK, Inc., announced today the U.S. launch of its new Reocor external pacemaker. The device is available in two models, for dual- and single-chamber pacing therapy, and offers individualized patient therapy, easy handling and flexibility in every detail. Reocor enriches BIOTRONIK's portfolio of high quality cardiovascular devices and sets a new standard of quality for external pacing therapy.

11 May 2012

Dyax introduces free Attack Tracker smartphone application for hereditary angioedema patients

Dyax Corp. today announced the launch of a free smartphone application for the iPhone - HAE Attack Tracker. This application allows HAE patients to keep detailed records of their disease related information, including emergency and physician contacts as well as individual attack data.

11 May 2012

Arno AR-42 for neurofibromatosis type 2 receives EMA orphan-drug designation

Arno Therapeutics, Inc. announced today that its investigational compound known as AR-42 has been granted orphan-drug designation by the European Medicines Agency's (EMA) Committee for Orphan Medicinal Products for the treatment of neurofibromatosis type 2 (NF2).

11 May 2012

Rule change has consequences for dialysis patients

A shift last year by the federal government in how it pays for drugs to treat dialysis patients may have had an unintended and potentially dire consequence, according to new research: a significant jump in blood transfusions for patients who now may not be getting enough of the medications.

11 May 2012

Lot of fat and few carbohydrates could have better effect on blood sugar levels, lipids in diabetics

People with Type 2 diabetes are usually advised to keep a low-fat diet. Now, a study at Linköping University shows that food with a lot of fat and few carbohydrates could have a better effect on blood sugar levels and blood lipids.

11 May 2012

Discrepancies between recommendations and implementation for management of cardiovascular risk factors

There are discrepancies between the recommendations for the management of cardiovascular risk factors and their implementation in clinical practice. In the latest issue of Deutsches Ärzteblatt International, Christof Prugger and his fellow authors present the results of the EUROASPIRE I, II and III surveys in the Münster region of Germany.

11 May 2012

Two types of stent systems are both effective in treating iliac artery disease

Two types of stent systems are both effective in treating patients who have severe forms of peripheral artery disease (PAD), according to results of the MOBILITY trial presented today as a late-breaking clinical trial at the SCAI 2012 Scientific Sessions.

11 May 2012

Medical Condition News

Study describes new compounds that inhibit PRMT1 enzyme

New insights into how body's innate immunity is triggered to create effective immune response

'Packing problem' could have a solution for cancer treatment

FDA advisory committee supports lorcaserin for weight management

FDA warns about 'liberation therapy' for multiple sclerosis

BioTrends tracks uptake of Yervoy and Zelboraf for advanced melanoma

Threshold for when to choose surgery over medical therapy for recurrent acute rhinosinusitis

Less invasive procedure for heart disease

Mylan introduces Atorvastatin Calcium in France, Belgium, UK, Ireland and the Netherlands

Positive results from Cytochroma CTAP101 Phase 2b clinical trial for CKD

Study supports catheter ablation as first-line treatment for paroxysmal atrial fibrillation

CTI receives EU conditional marketing authorization for Pixuvri to treat non-Hodgkin B-cell lymphomas

New discovery platform for antigen-specific monoclonal antibodies

BIOTRONIK launches new Reocor external pacemaker

Dyax introduces free Attack Tracker smartphone application for hereditary angioedema patients

Arno AR-42 for neurofibromatosis type 2 receives EMA orphan-drug designation

Rule change has consequences for dialysis patients

Lot of fat and few carbohydrates could have better effect on blood sugar levels, lipids in diabetics

Discrepancies between recommendations and implementation for management of cardiovascular risk factors

Two types of stent systems are both effective in treating iliac artery disease

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The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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