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Physically active video games can complement traditional exercise

The majority of consumers believe video games should encourage physical activity and that "physically active" video games can complement traditional exercise, according to a new survey released today by UnitedHealth Group.

11 May 2012

New combination therapy offers potential lifetime cure for advanced type 1 diabetes

City of Hope researchers developed a combination therapy to treat late-stage type 1 diabetes that appears to offer a potential lifetime cure for the disease without toxic side effects. The laboratory study is published in the May 9 edition of Science Translational Medicine.

11 May 2012

Cedars-Sinai’s first patient implanted with SynCardia temporary Total Artificial Heart

SynCardia Systems, Inc., manufacturer of the world's first and only FDA, Health Canada and CE (Europe) approved Total Artificial Heart, said today that Cedars-Sinai Medical Center in Los Angeles has discharged its first patient to be implanted with the SynCardia temporary Total Artificial Heart.

11 May 2012

PET imaging for sudden cardiac arrest can identify candidates for ICDs

New research from the University at Buffalo suggests that cardiologists may have a new way to identify patients who are at the highest risk of sudden cardiac arrest, and the most likely to benefit from receiving an implantable cardiac defibrillator (ICD).

11 May 2012

Top-line results from Takeda vedolizumab phase 3 trial on Crohn's disease

Takeda Pharmaceutical Company Limited today announced top-line results from the international, randomized, placebo-controlled, double-blind GEMINI II pivotal phase 3 trial. The trial evaluated vedolizumab in 1,115 patients with moderately to severely active Crohn's disease who have failed at least one conventional therapy, including TNFα antagonists.

11 May 2012

African-Americans with scleroderma have more antibodies linked to severe complications

A new analysis finds that compared to Caucasians, African-Americans with systemic scleroderma have more antibodies in the blood that are linked to severe complications and an increased likelihood of death. They say this finding, published today in Arthritis & Rheumatism, suggests physicians can use these disease markers to screen and treat scleroderma patients proactively.

11 May 2012

Excess brain activity contributes to amnestic mild cognitive impairment

A study led by a Johns Hopkins neuroscientist and published in the May 10 issue of the journal Neuron suggests a potential new therapeutic approach for improving memory and interrupting disease progression in patients with a form of cognitive impairment that often leads to full-blown Alzheimer's disease.

11 May 2012

NCSU scientists use light-activated molecules to turn gene expression on and off

Imagine being able to control genetic expression by flipping a light switch. Researchers at North Carolina State University are using light-activated molecules to turn gene expression on and off. Their method enables greater precision when studying gene function, and could lead to targeted therapies for diseases like cancer.

11 May 2012

Final results from Alnylam’s ALN-TTR01 Phase I trial on TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today final results from its completed Phase I clinical trial with ALN-TTR01, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis.

11 May 2012

Researchers identify over 2500 mRNA along dendrites and axons

How do we build a memory in the brain? It is well known that for animals (and humans) new proteins are needed to establish long-term memories. During learning information is stored at the synapses, the junctions connecting nerve cells.

11 May 2012

Interim results from Seattle Genetics’ ADCETRIS phase II trial on CTCL

Seattle Genetics, Inc. today announced that interim results from an investigator-sponsored phase II clinical trial of ADCETRIS (brentuximab vedotin) in patients with relapsed cutaneous T-cell lymphoma (CTCL) were presented at the Society for Investigative Dermatology annual meeting being held May 9-12, 2012 in Raleigh, NC.

11 May 2012

Viewpoints: Can Medicare taxes really fund student loans?; Daschle on diabetes and kids

In the case of the student loans, the Democrats' bill would require certain Americans -- high-income partners in small businesses that provide professional services, such as engineering or lobbying -- to pay payroll taxes on their share of the firm's profits. That's a long way of saying the bill would eliminate a tax-avoidance strategy that some small firms use to reduce their contributions to Social Security and Medicare.

11 May 2012

Administering vitamin K2 could possibly help patients with Parkinson's

Neuroscientist Patrik Verstreken, associated with VIB and KU Leuven, succeeded in undoing the effect of one of the genetic defects that leads to Parkinson's using vitamin K2. His discovery gives hope to Parkinson's patients.

11 May 2012

$EC approves CTI’s Pixuvri to treat multiply relapsed or refractory aggressive NHL$

EC approves CTI’s Pixuvri to treat multiply relapsed or refractory aggressive NHL

Cell Therapeutics, Inc. today announced that it has received conditional marketing authorization from the European Commission for Pixuvri (pixantrone) as monotherapy for the treatment of adult patients with multiply relapsed or refractory aggressive non-Hodgkin B-cell lymphomas.

11 May 2012

Ixmyelocel-T shows promise against progressive heart failure

An investigational therapy derived from a patient's own bone marrow stem cells improves heart function in some patients with progressive heart failure due to dilated cardiomyopathy (DCM), according to the results of a Phase 2a study presented today as a late-breaking clinical trial at the SCAI 2012 Scientific Sessions.

11 May 2012

Patients with mitral regurgitation live longer after surgery

Patients with mitral regurgitation, a type of valvular heart disease common in the elderly, are living longer after surgery, Yale School of Medicine researchers report in the journal Circulation: Cardiovascular Quality and Outcomes.

11 May 2012

NEJM publishes results from Celgene’s REVLIMID phase III studies on MM

Celgene International Sàrl, a subsidiary of Celgene Corporation, today announced that results from three phase III studies evaluating the use of continuous REVLIMID(lenalidomide) treatment in newly diagnosed multiple myeloma (MM) patients or maintenance treatment with lenalidomide following autologous stem cell transplant were published online in the May 10, 2012 edition of the New England Journal of Medicine.

11 May 2012

Maternal gluten sensitivity may increase risk of schizophrenia in children

Babies born to women with sensitivity to gluten appear to be at increased risk for certain psychiatric disorders later in life, according to research by scientists at Karolinska Institutet in Sweden and Johns Hopkins Children's Center in Baltimore.

11 May 2012

Rituximab does not appear to benefit children with INS

The drug rituximab, an antibody that targets the immune system and is often used to treat immune disorders such as lymphoma and arthritis, has recently emerged as a potential treatment for a childhood kidney disorder known as idiopathic nephrotic syndrome.

11 May 2012

ICD therapy significantly reduces mortality in patients with moderate heart failure

St. Jude Medical, Inc., a global medical device company, today announced results of the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial) 10-Year Follow-up Study at Heart Rhythm 2012, the Heart Rhythm Society's 33rd Annual Scientific Sessions in Boston. The study demonstrated implantable cardioverter defibrillator (ICD) therapy significantly reduces mortality for at least 11 years in patients with moderate heart failure (HF).

11 May 2012

Medical Condition News

Physically active video games can complement traditional exercise

New combination therapy offers potential lifetime cure for advanced type 1 diabetes

Cedars-Sinai’s first patient implanted with SynCardia temporary Total Artificial Heart

PET imaging for sudden cardiac arrest can identify candidates for ICDs

Top-line results from Takeda vedolizumab phase 3 trial on Crohn's disease

African-Americans with scleroderma have more antibodies linked to severe complications

Excess brain activity contributes to amnestic mild cognitive impairment

NCSU scientists use light-activated molecules to turn gene expression on and off

Final results from Alnylam’s ALN-TTR01 Phase I trial on TTR-mediated amyloidosis

Researchers identify over 2500 mRNA along dendrites and axons

Interim results from Seattle Genetics’ ADCETRIS phase II trial on CTCL

Viewpoints: Can Medicare taxes really fund student loans?; Daschle on diabetes and kids

Administering vitamin K2 could possibly help patients with Parkinson's

EC approves CTI’s Pixuvri to treat multiply relapsed or refractory aggressive NHL

Ixmyelocel-T shows promise against progressive heart failure

Patients with mitral regurgitation live longer after surgery

NEJM publishes results from Celgene’s REVLIMID phase III studies on MM

Maternal gluten sensitivity may increase risk of schizophrenia in children

Rituximab does not appear to benefit children with INS

ICD therapy significantly reduces mortality in patients with moderate heart failure

How can super-resolution technology help study neurotransmission?

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