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FDA approves Mallinckrodt's EXALGO (32 mg) sNDA to manage opioid-related pain

Zalicus Inc., a biopharmaceutical company that discovers and develops novel treatments for patients suffering from pain and immuno-inflammatory diseases, today announced that the U.S. Food and Drug Administration (FDA) has approved the supplemental new drug application (sNDA) filed by Mallinckrodt Inc., a subsidiary of Covidien plc, for the 32 mg dose strength of EXALGO (hydromorphone HCl) Extended-Release Tablets (CII), for the management of moderate to severe pain in opioid-tolerant patients requiring continuous, around-the-clock opioid analgesia for an extended period of time.

27 Aug 2012

Regulating microbes could help prevent diseases associated with obesity

Vaccines and antibiotics may someday join caloric restriction or bariatric surgery as a way to regulate weight gain, according to a new study focused on the interactions between diet, the bacteria that live in the bowel, and the immune system.

27 Aug 2012

Spironolactone should be considered as a treatment option in hypertensive patients with DHF

Mineralocorticoid receptor antagonists should be considered as a treatment option in hypertensive patients with diastolic heart failure, said Professor Burkert Pieske presenting results today of the Aldosterone Receptor Blockade in Diastolic Heart Failure (Aldo-DHF) study at ESC Congress 2012.

27 Aug 2012

Baylor Plano first hospital to merge MEM software and Epoch platform for atrial fibrillation therapy

Baylor Plano became the first hospital in the world on Friday to merge two highly advanced technologies for atrial fibrillation therapy.

27 Aug 2012

Renal denervation improves depression, QOL and stress in patients with resistant hypertension

Renal sympathetic denervation improves anxiety, depression, quality of life and stress in patients with resistant hypertension, according to research presented at ESC Congress 2012 by Dr Denise Fischer from Saarland University Hospital.

27 Aug 2012

Healthy behaviours decrease risk of high blood pressure by two thirds

Healthy behaviours regarding alcohol, physical activity, vegetable intake and body weight reduce the risk of hypertension by two thirds, according to research presented at the ESC Congress today.

27 Aug 2012

IABP does not improve blood pressure symptoms in patients with cardiogenic shock

A balloon pump inserted in the aorta is currently the most widely used support device in the treatment of cardiogenic shock and, since its introduction in 1968, has been used in several million people.

27 Aug 2012

Patients with psoriasis are at high risk of new-onset diabetes mellitus

Patients with psoriasis are at high risk of new-onset diabetes mellitus, according to research presented at ESC Congress 2012.

27 Aug 2012

Renal denervation safe and effective in patients with treatment resistant hypertension

Renal denervation leads to significant and sustained blood pressure reduction for up to 18 months in patients with treatment resistant hypertension, according to research presented at ESC Congress 2012.

27 Aug 2012

Consuming energy drinks can exert acute positive benefits on myocardial performance

Consuming energy drinks can exert acute positive benefits on myocardial performance, according to research presented today at the ESC Congress by Dr Matteo Cameli from University of Siena.

27 Aug 2012

Belly fat linked with increased risk of cardiovascular death in normal weight individuals

Normal weight individuals who carry weight concentrated in their belly have a higher death risk than obese individuals, according to research presented at ESC Congress 2012.

27 Aug 2012

New blood test can predict which heart failure patients would benefit from ICDs

A novel blood test that predicts sudden death risk in heart failure patients is set to help physicians decide which patients would benefit from implantable cardioverter defibrillators (ICDs).

27 Aug 2012

Obesity at diagnosis of breast cancer associated with increased risk of recurrence

Extra pounds-even within the overweight but not obese range-are linked to a higher risk of recurrence of the most common type of breast cancer despite optimal cancer treatment, according to a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

27 Aug 2012

New device can measure mass of individual molecules one at a time

A team led by scientists at the California Institute of Technology (Caltech) have made the first-ever mechanical device that can measure the mass of individual molecules one at a time.

27 Aug 2012

XJB-5-131 prevents secondary damage of severe traumatic brain injury

Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been impaired, according to a research team from the University of Pittsburgh School of Medicine, Graduate School of Public Health and Department of Chemistry in a report published online today in Nature Neuroscience.

27 Aug 2012

EC grants marketing authorization to Meda's Zyclara for treatment of actinic keratosis

Meda announced today that the European Commission (EC) has granted marketing authorization for Zyclara in the European Union. Zyclara (imiquimod 3.75% cream) is a patented product for the treatment of actinic keratosis.

27 Aug 2012

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

New data to be presented at the Annual Congress of the European Respiratory Society (ERS 2012), in Vienna, Austria, will shed light on the current and potential future role of tiotropium, the first once-daily long-acting inhaled anticholinergic for patients with Chronic Obstructive Pulmonary Disease (COPD).

27 Aug 2012

Profilin-1 gene influences survival time in Lou Gehrig's disease

A team of scientists, including faculty at the University of Massachusetts Medical School (UMMS), have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

27 Aug 2012

People with cardiac arrest during or shortly after exercise more likely to survive

People who have a cardiac arrest during or shortly after exercise are three times more likely to survive than those who have a cardiac arrest that is not exercise related, according to research presented at the ESC Congress 2012 today.

27 Aug 2012

Study confirms electrical storm as potent risk factor for death and impaired quality of life

Electrical storm (ES) is a potent risk factor for mortality and morbidity, according to research presented today at the ESC Congress 2012 by Dr Federico Guerra from Italy. Data was also presented on which patients are prone to developing ES and how effective current treatments are.

27 Aug 2012

Medical Condition News

FDA approves Mallinckrodt's EXALGO (32 mg) sNDA to manage opioid-related pain

Regulating microbes could help prevent diseases associated with obesity

Spironolactone should be considered as a treatment option in hypertensive patients with DHF

Baylor Plano first hospital to merge MEM software and Epoch platform for atrial fibrillation therapy

Renal denervation improves depression, QOL and stress in patients with resistant hypertension

Healthy behaviours decrease risk of high blood pressure by two thirds

IABP does not improve blood pressure symptoms in patients with cardiogenic shock

Patients with psoriasis are at high risk of new-onset diabetes mellitus

Renal denervation safe and effective in patients with treatment resistant hypertension

Consuming energy drinks can exert acute positive benefits on myocardial performance

Belly fat linked with increased risk of cardiovascular death in normal weight individuals

New blood test can predict which heart failure patients would benefit from ICDs

Obesity at diagnosis of breast cancer associated with increased risk of recurrence

New device can measure mass of individual molecules one at a time

XJB-5-131 prevents secondary damage of severe traumatic brain injury

EC grants marketing authorization to Meda's Zyclara for treatment of actinic keratosis

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

Profilin-1 gene influences survival time in Lou Gehrig's disease

People with cardiac arrest during or shortly after exercise more likely to survive

Study confirms electrical storm as potent risk factor for death and impaired quality of life

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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