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Scientists discover new type of dynamic change in human stem cells

A team led by scientists at The Scripps Research Institute and the University of California (UC) San Diego has discovered a new type of dynamic change in human stem cells.

4 May 2012

JAM-A protein a far more powerful clot inhibitor: Study

Cut your toe, and platelets -- those disc-shaped cells circulating in your blood -- rush to the scene, clumping together to plug the leak. But when an unwanted clot forms in an artery, and an overaccumulation of platelets blocks blood flow, a heart attack or stroke occurs, too often with fatal results.

4 May 2012

Hypoxia may be a primary cause of uncontrollable tumor growth in cancers

Low oxygen levels in cells may be a primary cause of uncontrollable tumor growth in some cancers, according to a new University of Georgia study. The authors' findings run counter to widely accepted beliefs that genetic mutations are responsible for cancer growth.

4 May 2012

Study captures positive experiences of people with bipolar disorder

The problems of living with bipolar have been well documented, but a new study by Lancaster University has captured the views of those who also report highly-valued, positive experiences of living with the condition.

4 May 2012

Scientists discover key element in DNA repair mechanism

Scientists from the Kavli Institute of Nanoscience at Delft University of Technology have discovered a key element in the mechanism of DNA repair.

4 May 2012

CAPE arrests growth of prostate cancer cells and tumors in mice

An over-the-counter natural remedy derived from honeybee hives arrests the growth of prostate cancer cells and tumors in mice, according to a new paper from researchers at the University of Chicago Medicine.

4 May 2012

FDA issues Complete Response Letter to Alexza’s ADASUVE NDA

Alexza Pharmaceuticals, Inc. announced today that it has received a Complete Response Letter (CRL) from the U.S. Food and Drug Administration (FDA) regarding its New Drug Application (NDA) for ADASUVE (loxapine) inhalation powder, 5 mg and 10 mg.

4 May 2012

Topera Medical to showcase RhythmView system at HRS annual meeting

Topera Medical today announced that its FDA-cleared RhythmView 3D mapping and diagnostic system will be featured in 16 scientific presentations at the 33rd Annual Scientific Sessions of the Heart Rhythm Society (HRS), May 9-12 in Boston.

4 May 2012

Repeated blows to the head associated with long term cognitive, pathologic changes

NFL great Junior Seau's apparent suicide might shock the sports world, but to neurosurgeons and neurologists accustomed to seeing an increase in the incidence of concussions, especially among football players, the news isn't as surprising.

3 May 2012

Scientists address mental health and well-being at Association for Psychological Science's annual meeting

Are our existing treatments for mental health issues working? Can we design new and better approaches to intervention? Can we even tell which factors promote mental health? Clinical psychological scientists will be addressing these and many other questions related to mental health and well-being at the Association for Psychological Science's 24th annual meeting in Chicago, May 24-27, 2012.

3 May 2012

Kessler Foundation scientists to share new findings at international multiple sclerosis congress

Kessler Foundation will be represented by four scientists at the inaugural International Congress on Cognition in Multiple Sclerosis to be held at the Congress Center in Bordeaux, France on May 11 & 12, 2012.

3 May 2012

State of health, not age, should decide treatment for cancer

In a study of patients 65 and older with non-small-cell lung cancer (NSCLC), younger patients were more likely to receive treatment than older patients, regardless of overall health and prognosis.

3 May 2012

Therapy to halt symptoms in Parkinson's patients

Parkinson's disease, a disorder which affects movement and cognition, affects over a million Americans, including actor Michael J. Fox, who first brought it to the attention of many TV-watching Americans. It's characterized by a gradual loss of neurons that produce dopamine. Mutations in the gene known as DJ-1 lead to accelerated loss of dopaminergic neurons and result in the onset of Parkinson's symptoms at a young age.

3 May 2012

Nanoparticle carriers successfully deliver therapeutic doses of cancer drug

Current nanomedicine research has focused on the delivery of established and novel therapeutics. But a UNC team is taking a different approach. They developed nanoparticle carriers to successfully deliver therapeutic doses of a cancer drug that had previously failed clinical development due to pharmacologic challenges.

3 May 2012

Senior Health Implementation Center to disseminate Aging Brain Care Program tools

The resources developed for an innovative collaborative model of dementia care, which reduces emergency room and hospital visits and improves the quality of care for those with dementia, are now available to institutions, clinicians and caregivers around the globe with the establishment of the Aging Brain Care Program.

3 May 2012

Cardiac testing important for lung disease prognosis, treatment

A simple test for heart disease risk can go a long way toward determining the long-term prognosis for people with chronic obstructive pulmonary disease, according to UC Irvine researchers.

3 May 2012

Non-invasive imaging technique measures specific brain chemical changes

Alzheimer's disease (AD) is a major neurodegenerative disorder that affects millions of people worldwide. New and accurate techniques for early diagnosis are critical. Pravat K. Mandal, PhD, and his colleagues have developed a completely non-invasive brain imaging technique to measure specific brain chemical changes. This provides a signature of the early stages of AD from the hippocampal region of the brain.

3 May 2012

Large-scale, patient-specific simulations of blood function

Having a virtual copy of a patient's blood in a computer would be a boon to researchers and doctors. They could examine a simulated heart attack caused by blood clotting in a diseased coronary artery and see if a drug like aspirin would be effective in reducing the size of such a clot.

3 May 2012

Reuters examines cancer in Africa

Reuters examines cancer in Africa, writing, "Most of Africa's around 2,000 languages have no word for cancer. The common perception in both developing and developed countries is that it's a disease of the wealthy world, where high-fat, processed-food diets, alcohol, smoking and sedentary lifestyles fuel tumor growth."

3 May 2012

A better understanding of link between glycemic variability and psychological disorders needed

When blood sugar levels in diabetes are poorly controlled, patients tend to have more complications such as depression and other mood disturbances, including anxiety and anger, and a lower overall quality of life.

3 May 2012