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Researchers discover new cause of congenital myopathy

University of Michigan researchers have discovered a new cause of congenital myopathy: a mutation in a previously uncharacterized gene, according to research published this month in the American Journal of Human Genetics.

26 Jul 2012

Studies look at surgical site infections and hyperglycemia

Two recent studies in the July issues of the Journal of Bone and Joint Surgery (JBJS) looked at surgical site infections and hyperglycemia, the technical term for high blood glucose, or high blood sugar.

26 Jul 2012

Everyday words that describe feelings lost in dementia

Dementia can affect a person’s ability to recognise the meaning of common emotional words such as ‘thrilled’ and ‘annoyed’, according to new research.

25 Jul 2012

Single event of brain trauma can lead to Alzheimer’s

A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer’s disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer’s. The paper, published in The Journal of Neuroscience, identifies the complex mechanisms that result in a rapid and robust post-injury elevation of the enzyme, BACE1, in the brain. These results may lead to the development of a drug treatment that targets this mechanism to slow the progression of Alzheimer’s disease.

25 Jul 2012

Cepheid launches new Xpert BCR-ABL Monitor test

Cepheid today announced the release of an updated Xpert BCR-ABL Monitor test, now incorporating lot-specific standardization using the WHO (World Health Organization) BCR-ABL standards.

25 Jul 2012

Karyopharm commences two KPT-330 phase 1 studies in cancers

Karyopharm Therapeutics Inc., a leader in the new field of nuclear transport modulators, announced dosing of patients in the first-in-human clinical trials with KPT-330.

25 Jul 2012

Increased distribution of neurosurgeons may reduce risk of motor vehicle accident-related deaths

Researchers at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire have found an association between increasing the distribution of neurosurgeons throughout the United States and decreasing the risk of death from motor vehicle accidents (MVAs).

25 Jul 2012

New cell regeneration method uses gene therapy to repair bone tissue

Researchers at the Royal College of Surgeons in Ireland (RCSI) have developed a new method of repairing bone using synthetic bone graft substitute material, which combined with gene therapy, can mimic real bone tissue and has potential to regenerate bone in patients who have lost large areas of bone from either disease or trauma.

25 Jul 2012

MASL protein from plant's seeds may halt spread of melanoma

An international team of scientists led by Gary Goldberg, PhD, of the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine (UMDNJ-SOM), has found that a protein from the seeds of a plant used for centuries in traditional medicines may be able to halt the spread of melanoma, a lethal form of skin cancer.

25 Jul 2012

EntreMed commences ENMD-2076 Phase 2 study in triple-negative breast cancer

EntreMed, Inc., a clinical-stage pharmaceutical company, announced today the initiation of a dual-institutional Phase 2 study of ENMD-2076 in triple-negative breast cancer. Jennifer R. Diamond, MD at the University of Colorado serves as the principal investigator for the study.

25 Jul 2012

WASC accredits Cedars-Sinai PhD program in biomedical sciences and translational medicine

The Graduate Program in Biomedical Sciences and Translational Medicine at Cedars-Sinai has been accredited by the Western Association of Schools and Colleges, an affirmation that the PhD-awarding educational effort meets the most rigorous standards of higher learning.

25 Jul 2012

Study uses photodynamic therapy to ablate cardiac myocytes responsible for arrhythmias

University of Michigan heart researchers are shedding light on a safer method for steadying an abnormal heart rhythm that prevents collateral damage to healthy cells.

25 Jul 2012

Study uncovers pathways by which yoga impacts biological processes

Six months ago, researchers at UCLA published a study that showed using a specific type of yoga to engage in a brief, simple daily meditation reduced the stress levels of people who care for those stricken by Alzheimer's and dementia. Now they know why.

25 Jul 2012

Daily Beast profiles George W. Bush's post-presidency global health work

The Daily Beast's "U.S. Policy" blog profiles former president George W. Bush's post-presidency work in global health through the Bush Institute, which "houses a variety of programs under the broad headings of global health, education reform, economic growth, and advancing human freedom, areas that advance Bush's interests and reflect his presidency."

25 Jul 2012

NBTI participates in ICT-107 phase II trial for glioblastoma multiforme

Researchers at Northwestern Brain Tumor Institute (NBTI) are seeking to understand if a vaccine made from a patient's own blood cells may slow the growth of a type of brain tumor.

25 Jul 2012

EC grants Marketing Authorisation to Boehringer Ingelheim and Lilly’s Jentadueto for diabetes

Boehringer Ingelheim and Eli Lilly and Company received Marketing Authorisation from the European Commission for Jentadueto which combines the DPP-4 inhibitor, linagliptin and metformin in a single tablet.

25 Jul 2012

Malaria misdiagnosis in parts of Asia

Substantial overdiagnosis and mistreatment of malaria is evident in south and central Asia, warns a study published on bmj.com today.

25 Jul 2012

Sunbed users at a 20% increased relative risk of skin cancer

Of 63,942 new cases of cutaneous melanoma (a form of skin cancer) diagnosed each year in Europe an estimated 3,438 (5.4%) are related to sunbed use. Sunbed users are at a 20% increased relative risk of skin cancer compared with those who have never used a sunbed. This risk doubles if they start before the age of 35 and experts warn that “tougher actions” are needed to reduce this risk.

25 Jul 2012

Insights into link between fat-hoarding genes and ancient diet

Why do Native Americans experience high rates of diabetes? A common theory is that they possess fat-hoarding "thrifty genes" left over from their ancestors - genes that were required for survival during ancient cycles of feast and famine, but that now contribute to the disease in a modern world of more fatty and sugary diets.

25 Jul 2012

Researchers discover important link between sodium and calcium

The scientific community has always wanted to know why people who eat high-salt diets are prone to developing medical problems such as kidney stones and osteoporosis.

25 Jul 2012