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New tool uses fluorescence to distinguish cancerous tissue from normal one in low-grade tumors

A new probe developed collaboratively at Norris Cotton Cancer Center and Dartmouth College's Thayer School of Engineering uses an innovative fluorescence-reading technology to help brain surgeons distinguish cancerous tissue from normal tissue. The probe tool, now already in use at the Cancer Center for brain surgery, may one day be used for surgeries for a variety of cancers.

25 Jul 2012

Giving patients a new immune system can cure Crohn's disease

Researchers at Fred Hutchinson Cancer Research Center have opened a clinical trial to test the theory that giving a patient a new immune system can cure severe cases of Crohn's disease, a chronic inflammatory condition of the gastrointestinal tract.

25 Jul 2012

RhoC gene promotes breast cancer stem cell progression

Researchers at the University of Michigan Comprehensive Cancer Center have found that a cancer gene linked to aggressive spread of the disease promotes breast cancer stem cells. The finding implies a new way to target the behavior of these lethal cells.

25 Jul 2012

Moderate-to-severe TBI can disrupt proteins that regulate enzyme associated with Alzheimer's

A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer's disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer's.

25 Jul 2012

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Take a millionth of a human brain and squeeze it into a special chamber the size of a mustard seed. Link it to a second chamber filled with cerebral spinal fluid and thread both of them with artificial blood vessels in order to create a microenvironment that makes the neurons and other brain cells behave as if they were in a living brain. Then surround the chambers with a battery of sensors that monitor how the cells respond when exposed to minute quantities of dietary toxins, disease organisms or new drugs under development.

25 Jul 2012

LSDF announces $570,000 in awards to support commercialization of new health-related products

The Life Sciences Discovery Fund (LSDF) today announced nearly $570,000 in awards in its inaugural corporate grant program to support commercialization of new health and health-care products by four early-stage Washington-based companies.

25 Jul 2012

New algorithm can help scientists predict gene and drug interactions

Researchers from Mount Sinai School of Medicine have developed a new computational method that will make it easier for scientists to identify and prioritize genes, drug targets, and strategies for repositioning drugs that are already on the market. By mining large datasets more simply and efficiently, researchers will be able to better understand gene-gene, protein-protein, and drug/side-effect interactions. The new algorithm will also help scientists identify fellow researchers with whom they can collaborate.

25 Jul 2012

EMA COMP issues positive opinion to Albireo for A4250

Albireo AB, a biopharmaceutical company specializing in gastroenterology, today announced that the European Medicines Agency Committee for Orphan Medicinal Products (COMP) has issued a positive opinion on an application for orphan medicinal product status for the company's lead hepatology candidate, A4250.

25 Jul 2012

Hypoxic lung environment increases HIF-2a tumor growth signaling

In addition to the well-known risk factor of smoking, chronic obstructive pulmonary disease (COPD) increases lung cancer risk.

25 Jul 2012

Aeterna Zentaris files request with FDA for Fast Track designation for AEZS-130

Aeterna Zentaris Inc. today announced that it has filed a request with the United States Food and Drug Administration (FDA) for Fast Track designation for its oral ghrelin agonist, AEZS-130, as a diagnostic test for adult growth hormone deficiency (AGHD).

25 Jul 2012

Researchers plan to develop new rehabilitation tool for stroke victims

Researchers at the University of Luxembourg, along with their international partners, want to develop an easy-to-use, self-motivating tool that stroke patients can use in their rehabilitation process. The 4.4 million euro project is funded by the European Commission Seventh Framework Programme.

25 Jul 2012

New classification scheme for psychiatric symptoms

The traditional approach to psychiatric diagnosis is based on grouping patients on the basis of symptom clusters. This approach to diagnosis has a number of problems, as symptoms are not necessarily specific to a single diagnosis.

25 Jul 2012

Colonoscopy with polypectomy decreases colorectal cancer incidence and mortality

A study from researchers in Switzerland found that colonoscopy with polypectomy significantly reduces colorectal cancer incidence and colorectal cancer-related death in the general population.

25 Jul 2012

Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout

BioCryst Pharmaceuticals, Inc. announced favorable 52-week safety results and sustained efficacy from the extension phase of its randomized Phase 2b trial of ulodesine (BCX4208) added to allopurinol in patients with gout who had failed to reach the serum uric acid (sUA) therapeutic goal of <6 mg/dL on allopurinol alone, as well as positive Phase 2 safety results in patients with mild to moderate renal impairment.

25 Jul 2012

South Asians have higher levels of blood sugar than Europeans: New diabetes study

A new diabetes study at the University of Leicester has discovered that South Asians (people of Indian, Pakistani, Bangladeshi and Sri Lanka origin) have higher levels of blood sugar than white Europeans independent of risk factors that influence sugar levels.

24 Jul 2012

New large animal model for human cancer studies

A naturally occurring line of immunodeficient pigs can support the growth of human tumors injected under their skin, offering a promising new large animal model for studying human cancers and testing new drugs and treatment strategies.

24 Jul 2012

Jersey Shore continues to provide outstanding cardiac surgery services

The 2012 Cardiac Surgery in New Jersey report, recently released by the New Jersey Department of Health & Senior Services (NJDHSS), shows Jersey Shore University Medical Center continues to provide outstanding cardiac surgery services, building on its exceptional track record in coronary artery bypass graft (CABG) surgery mortality rates.

24 Jul 2012

Study identifies MDM4 protein as promising target for treatment of melanoma

A melanoma is a malignant form of skin cancer and is one of the most aggressive types of tumors there is. Treatment is particularly difficult, because melanomas are usually resistant against conventional chemotherapy treatments.

24 Jul 2012

Biokine receives FDA Orphan Drug designation for BKT140 to treat hematological cancers

Biokine Therapeutics Ltd. announced today that it has received Orphan Drug designation from the US Food and Drug Administration (FDA) for the mobilization of hematopoietic stem cells from bone marrow into peripheral blood for collection and subsequent transplantation in patients with hematological cancers.

24 Jul 2012

Blood flow in blocked arteries to extremities improved by new angioplasty procedure

Patients with blocked arteries to their extremities, known as peripheral artery disease (PAD) or critical limb ischemia (CLI), may now find relief from lower leg pain and wounds caused by impaired leg artery circulation with the previously unproven therapy, percutaneous transluminal angioplasty (PTA).

24 Jul 2012

Medical Condition News

New tool uses fluorescence to distinguish cancerous tissue from normal one in low-grade tumors

Giving patients a new immune system can cure Crohn's disease

RhoC gene promotes breast cancer stem cell progression

Moderate-to-severe TBI can disrupt proteins that regulate enzyme associated with Alzheimer's

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

LSDF announces $570,000 in awards to support commercialization of new health-related products

New algorithm can help scientists predict gene and drug interactions

EMA COMP issues positive opinion to Albireo for A4250

Hypoxic lung environment increases HIF-2a tumor growth signaling

Aeterna Zentaris files request with FDA for Fast Track designation for AEZS-130

Researchers plan to develop new rehabilitation tool for stroke victims

New classification scheme for psychiatric symptoms

Colonoscopy with polypectomy decreases colorectal cancer incidence and mortality

Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout

South Asians have higher levels of blood sugar than Europeans: New diabetes study

New large animal model for human cancer studies

Jersey Shore continues to provide outstanding cardiac surgery services

Study identifies MDM4 protein as promising target for treatment of melanoma

Biokine receives FDA Orphan Drug designation for BKT140 to treat hematological cancers

Blood flow in blocked arteries to extremities improved by new angioplasty procedure

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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