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Lung cancer molecular subtypes correlate with genetic alterations, patient's response to therapy

Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient's individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient's response to therapy.

14 May 2012

Findings reveal racial disparities in pre-hospital care for cardiac arrest

Black cardiac arrest victims who are stricken outside hospitals are less likely to receive bystander CPR and defibrillation on the scene than white patients, according to research that will be presented by a research team from the Perelman School of Medicine at the University of Pennsylvania today at the annual meeting of Society for Academic Emergency Medicine.

14 May 2012

Novel heart monitoring device helps ER patients avoid unnecessary follow-up care

A study conducted at Scripps Health has found that a novel new heart monitoring device helped emergency room patients avoid unnecessary follow-up care. Scripps Health electrophysiologist Steven Higgins, MD, presented findings of the study titled, "Prevalence of Arrhythmias in Emergency Department Patients Discharged Using a Novel Ambulatory Cardiac Monitor", today at the Heart Rhythm Society's 33rd Annual Scientific Sessions in Boston.

14 May 2012

Even mild head injuries can cause abnormalities in brain function

Even mild head injuries can cause significant abnormalities in brain function that last for several days, which may explain the neurological symptoms experienced by some individuals who have experienced a head injury associated with sports, accidents or combat, according to a study by Virginia Commonwealth University School of Medicine researchers.

14 May 2012

Women more likely to suffer PTSD after being discharged from ICU

Women are more likely to suffer post-traumatic stress than men after leaving an intensive care unit (ICU), finds a new study published in BioMed Central's open access journal Critical Care. However, psychological and physical 'follow-up' can reduce both this and post-ICU depression.

14 May 2012

New system may help restore vision in eye diseases

Using tiny solar-panel-like cells surgically placed underneath the retina, scientists at the Stanford University School of Medicine have devised a system that may someday restore sight to people who have lost vision because of certain types of degenerative eye diseases.

14 May 2012

Mild head injuries can cause structural disruption of axons in the brain

11 May 2012

NBHA commends FDA for continuing investigation of bisphosphonate treatment for osteoporosis

In response to today's Perspective pieces published in the New England Journal Of Medicine, the National Bone Health Alliance (NBHA), a public-private partnership bringing together the expertise and resources of its 42 members from the private and non-profit sectors to collectively advance bone health and prevent disease, commends the U.S. Food and Drug Administration (FDA) for continuing to investigate the risks and benefits of long-term bisphosphonate treatment.

11 May 2012

Study describes new compounds that inhibit PRMT1 enzyme

Scientists at The Scripps Research Institute have found the first chemical compounds that act to block an enzyme that has been linked to inflammatory conditions such as asthma and arthritis, as well as some inflammation-promoted cancers.

11 May 2012

New insights into how body's innate immunity is triggered to create effective immune response

Singapore scientists from Bioprocessing Technology Institute (BTI) under the Agency of Science, Technology and Research (A*STAR) have for the first time, identified the molecular 'switch' that directly triggers the body's first line of defence against pathogens, more accurately known as the body's "innate immunity".

11 May 2012

'Packing problem' could have a solution for cancer treatment

A hidden facet of a math problem that goes back to Sanskrit scrolls has just been exposed by nanotechnology researchers at the University of Michigan and the University of Connecticut.

11 May 2012

FDA advisory committee supports lorcaserin for weight management

Arena Pharmaceuticals, Inc. and Eisai Inc. announced today that the US Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee voted 18 to 4, with one abstention, that the available data demonstrate that the potential benefits of lorcaserin outweigh the potential risks when used long-term in a population of overweight and obese individuals.

11 May 2012

FDA warns about 'liberation therapy' for multiple sclerosis

The U.S. Food and Drug Administration is alerting health care professionals and patients about injuries and death associated with the use of an experimental procedure sometimes called "liberation therapy" or the "liberation procedure" to treat chronic cerebrospinal venous insufficiency (CCSVI).

11 May 2012

BioTrends tracks uptake of Yervoy and Zelboraf for advanced melanoma

BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, has released findings from the second wave of its LaunchTrends® Yervoy and Zelboraf report, in which 103 U.S.-based medical oncologists were surveyed about their current and expected treatment patterns in advanced melanoma.

11 May 2012

Threshold for when to choose surgery over medical therapy for recurrent acute rhinosinusitis

A study in the May 2012 issue of Otolaryngology-Head and Neck Surgery suggests a threshold for when to choose surgery over medical therapy for recurrent acute rhinosinusitis (RARS) based on the patients' lost productivity in response to RARS and each treatment strategy.

11 May 2012

Less invasive procedure for heart disease

Doctors at Regions Hospital have begun performing a less invasive procedure for heart disease. Transcatheter aortic valve replacement (TAVR) was approved last November by the U.S. Food and Drug Administration for elderly patients who are too frail or too old for open heart surgery. The device is not approved for patients who are eligible for open heart surgery.

11 May 2012

Mylan introduces Atorvastatin Calcium in France, Belgium, UK, Ireland and the Netherlands

Mylan Inc. today announced that it has launched Atorvastatin Calcium Tablets, 10 mg, 20 mg, 40 mg and 80 mg in France, Belgium, the UK, the Netherlands and Ireland.

11 May 2012

Positive results from Cytochroma CTAP101 Phase 2b clinical trial for CKD

Cytochroma today announced positive clinical trial results for its lead product, CTAP101 Capsules. In a recently completed Phase 2b trial, CTAP101 Capsules effectively and safely lowered elevated plasma intact parathyroid hormone (iPTH) in patients with Stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

11 May 2012

Study supports catheter ablation as first-line treatment for paroxysmal atrial fibrillation

Patients with the heart rhythm disorder atrial fibrillation (AFib) who received first-line catheter ablation treatment had a longer arrhythmia-free interval than patients receiving antiarrhythmic drugs, the standard first-line treatment.

11 May 2012

CTI receives EU conditional marketing authorization for Pixuvri to treat non-Hodgkin B-cell lymphomas

CellTherapeutics today announced that it has received conditional marketing authorization from the European Commission for Pixuvri (pixantrone) as monotherapy for the treatment of adult patients with multiply relapsed or refractory aggressive non-Hodgkin B-cell lymphomas. Pixuvri is the first approved treatment in the European Union in this patient setting.

11 May 2012

Medical Condition News

Lung cancer molecular subtypes correlate with genetic alterations, patient's response to therapy

Findings reveal racial disparities in pre-hospital care for cardiac arrest

Novel heart monitoring device helps ER patients avoid unnecessary follow-up care

Even mild head injuries can cause abnormalities in brain function

Women more likely to suffer PTSD after being discharged from ICU

New system may help restore vision in eye diseases

Mild head injuries can cause structural disruption of axons in the brain

NBHA commends FDA for continuing investigation of bisphosphonate treatment for osteoporosis

Study describes new compounds that inhibit PRMT1 enzyme

New insights into how body's innate immunity is triggered to create effective immune response

'Packing problem' could have a solution for cancer treatment

FDA advisory committee supports lorcaserin for weight management

FDA warns about 'liberation therapy' for multiple sclerosis

BioTrends tracks uptake of Yervoy and Zelboraf for advanced melanoma

Threshold for when to choose surgery over medical therapy for recurrent acute rhinosinusitis

Less invasive procedure for heart disease

Mylan introduces Atorvastatin Calcium in France, Belgium, UK, Ireland and the Netherlands

Positive results from Cytochroma CTAP101 Phase 2b clinical trial for CKD

Study supports catheter ablation as first-line treatment for paroxysmal atrial fibrillation

CTI receives EU conditional marketing authorization for Pixuvri to treat non-Hodgkin B-cell lymphomas

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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