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Researchers create first 3D structure of key cancer protein

Cancer Research UK scientists have created the first 3D structure of a key protein that protects against the development of cancer, according to research published in Nature Structural & Molecular Biology today.

22 Jan 2012

SSRI use raises risk of fall among elderly with dementia: Study

A new study reveals that nursing home residents with dementia who use selective serotonin reuptake inhibitors (SSRIs) have an increased risk of having a fall that causes injury compared with those who do not use SSRIs. Additionally those using average doses have 3 times the risk compared with nonusers, the authors, led by Carolyn S. Sterke, from Erasmus University Medical Center, Rotterdam, the Netherlands, report. Authors write, “Even at low doses, SSRIs are associated with increased risk of an injurious fall in nursing home residents with dementia.”

22 Jan 2012

Proposed new definition may affect individuals who qualify for autism diagnosis

Getting an autism diagnosis could be more difficult in 2013 when a revised diagnostic definition goes into effect. The proposed changes may affect the proportion of individuals who qualify for a diagnosis of autism spectrum disorder, according to preliminary data presented by Yale School of Medicine researchers at a meeting of the Icelandic Medical Association.

21 Jan 2012

First genome-wide study of high-altitude adaptations in Ethiopians

Over many generations, people living in the high-altitude regions of the Andes or on the Tibetan Plateau have adapted to life in low-oxygen conditions. Living with such a distinct and powerful selective pressure has made these populations a textbook example of evolution in action, but exactly how their genes convey a survival advantage remains an open question. Now, a University of Pennsylvania team has made new inroads to answering this question with the first genome-wide study of high-altitude adaptations within the third major population to possess them: the Amhara people of the Ethiopian Highlands.

21 Jan 2012

Younger women with breast cancer experience a decrease in health-related QOL

Younger women with breast cancer experience a decrease in their health-related quality of life (QOL), associated with increased psychological distress, weight gain, a decline in their physical activity, infertility and early onset menopause, according to a study published January 20 in the Journal of the National Cancer Institute.

21 Jan 2012

Doctors can use tactile imaging sensor for early detection of cancerous tumors

A key part of a medical patient's physical examination is performed through touch, but the doctor can only glean so much information from what he feels. That's why Temple University researchers have created a prototype device that will not only emulate human tactile sensation, but quantify it as well.

21 Jan 2012

Study evaluates whether PWB predicts negative affectivity in fibromyalgia

Fibromyalgia (FM) is a stress-related functional somatic syndrome consisting of musculoskeletal pain and tenderness, and additional symptoms such as fatigue and difficulty concentrating. Factors such as ill-being, often assessed as negative affectivity, may follow, increasing the risk of unhealthy and dysfunctional lifestyles.

21 Jan 2012

EMA CHMP issues positive opinion to MSD's REMICADE for treatment of pediatric UC

MSD today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion recommending the use of REMICADE (infliximab) in the treatment of severely active ulcerative colitis (UC) in pediatric patients ages 6 to 17 years, who have had an inadequate response to conventional therapy, including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies.

21 Jan 2012

Risperdal lawsuit settlement: Largest Medicaid fraud case in Texas

Texas and Janssen Pharmaceuticals reach a $158 million settlement on a suit claiming that the company lied about the efficacy of the anti-psychotic medicine.

21 Jan 2012

Adding oxaliplatin to adjuvant 5FU improves survival of patients with stage III colon cancer

Stage III colon cancer patients in the general population who receive adjuvant treatment for the disease have an improved rate of survival when oxaliplatin is added to 5-fluorouracil (5FU), according to a study published Jan. 20 in the Journal of the National Cancer Institute.

21 Jan 2012

Scientists develop new way to create electromagnetic T-rays for medical scanners

Scientists have developed a new way to create electromagnetic Terahertz (THz) waves or T-rays - the technology behind full-body security scanners. The researchers behind the study, published recently in the journal Nature Photonics, say their new stronger and more efficient continuous wave T-rays could be used to make better medical scanning gadgets and may one day lead to innovations similar to the 'tricorder' scanner used in Star Trek.

21 Jan 2012

Awake ECMO may be an effective bridging strategy for lung transplantation candidates

Extracorporeal membrane oxygenation (ECMO) support in awake, non-intubated patients may be an effective strategy for bridging patients to lung transplantation, according to a new study from Germany.

21 Jan 2012

Study documents a need for increased injury prevention efforts in many popular activities for kids

A new study by researchers at the Johns Hopkins Center for Injury Research and Policy and the Centers for Disease Control and Prevention (CDC) documents a need for increased injury prevention efforts in many of the most popular activities for kids (walking, bicycling, swimming, sports and playground use) in the United States.

21 Jan 2012

Viewpoints: An endorsement for Gingrich; Paula Deen and diabetes

As the attorney general who filed the lawsuit challenging the constitutionality of the Patient Protection and Affordable Care Act that is now before the U.S. Supreme Court, I care deeply about repealing and replacing the law. For this to happen, President Obama has to be replaced. There is no other candidate as well equipped as Newt Gingrich to take it to Barack Obama in a health care debate.

21 Jan 2012

NHS Choices launches new food allergy and intolerance myth buster tool

To mark food allergy and intolerance awareness week, NHS Choices, the health information website for the NHS, has launched a new tool to help dispel common myths around food allergy and intolerance.

21 Jan 2012

Poor and uneducated smokers face difficulty in quitting

Quitting smoking is never easy. However, when you're poor and uneducated, kicking the habit for good is doubly hard, according to a new study by a tobacco dependence researcher at The City College of New York.

21 Jan 2012

Exercise fails to improve glucose metabolism in autophagy-deficient mice

The health benefits of exercise on blood sugar metabolism may come from the body's ability to devour itself, UT Southwestern Medical Center researchers report in the journal Nature.

21 Jan 2012

Minuscule amounts of ethanol can double C. elegans' life span

Minuscule amounts of ethanol, the type of alcohol found in alcoholic beverages, can more than double the life span of a tiny worm known as Caenorhabditis elegans, which is used frequently as a model in aging studies, UCLA biochemists report. The scientists said they find their discovery difficult to explain.

21 Jan 2012

FDA allows marketing of Stratify JCV Antibody ELISA test for PML

Today, the U.S. Food and Drug Administration allowed marketing of the first test to help determine the risk for a rare brain infection called progressive multifocal leukoencephalopathy (PML) in people using the drug Tysabri (natalizumab) to treat multiple sclerosis (MS) or Crohn's disease.

21 Jan 2012

ICAEL accredits Gottlieb for echocardiography

Gottlieb Memorial Hospital has received a three-year accreditation in the areas of Adult Stress and Adult Transthoracic Echocardiography from the Intersocietal Commission for the Accreditation of Echocardiography Laboratories.

21 Jan 2012