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FDA approves product label change for Biogen Idec's TYSABRI to treat MS

Today Biogen Idec and Elan Corporation, plc announced that the U.S. Food and Drug Administration (FDA) has approved a product label change for TYSABRI that will help enable individual benefit risk assessment for patients with multiple sclerosis.

21 Jan 2012

New data from Infinity saridegib and gemcitabine Phase 1b/2 combination trial on pancreatic cancer

Infinity Pharmaceuticals, Inc. today announced updated data from the Phase 1b portion of an ongoing Phase 1b/2 clinical trial of saridegib in combination with the chemotherapy gemcitabine in patients with previously untreated, metastatic pancreatic cancer.

20 Jan 2012

Exposure to phthalates may increase risk of obesity in young children

Researchers from the Children's Environmental Health Center at The Mount Sinai Medical Center in New York have found an association between exposure to the chemical group known as phthalates and obesity in young children - including increased body mass index (BMI) and waist circumference.

20 Jan 2012

Positive preliminary data from Exelixis' cabozantinib phase 2 trial on HCC

Exelixis, Inc. today reported positive preliminary data from the cohort of hepatocellular carcinoma (HCC) patients participating in the ongoing phase 2 randomized discontinuation trial (RDT) of cabozantinib.

20 Jan 2012

Combination of gefitinib and miRNA-inhibitor might effectively treat NSCLC

New research published in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.

20 Jan 2012

Novel imaging platform reveals new details on aggressive cancer development

When cancers become aggressive and spread they are the most deadly. Unfortunately, little is known about how to stop this development. A new imaging platform developed by Lawson Health Research Institute's Drs. Ann Chambers and John Lewis is providing insight into just that - the exact moment when cancer cells turn deadly.

20 Jan 2012

Cedars-Sinai's annual Brainworks program to take place on Feb. 13

Taking turns gazing into a surgical microscope, 130 seventh- and eighth-graders from Los Angeles area schools will see a phantom skull and perform virtual surgery - and many could catch a glimpse of the future.

20 Jan 2012

Novel nano-carrier platform shows promise for cancer drug delivery

A new class of nanoparticles, synthesized by a UC Davis research team to prevent premature drug release, holds promise for greater accuracy and effectiveness in delivering cancer drugs to tumors. The work is published online in Angewandte Chemie, a leading international chemistry journal.

20 Jan 2012

WSU professors receive NSF grant to develop math model of liver metabolism

Predicting problems in one of the body's most complex organs soon may become easier because of work being done by Wayne State University researchers.

20 Jan 2012

Making Cancer History seminar to take place on Feb. 11

Cancer experts from The University of Texas MD Anderson Cancer Center return to West Palm Beach Feb. 11 for the institution's annual Making Cancer History seminar. The event, in the Cohen Pavilion of the Raymond F. Kravis Center for the Performing Arts, 701 Okeechobee Blvd., begins at 8:30 a.m. with a breakfast buffet.

20 Jan 2012

Scientists discover unexpected way in which a neutrophil prepares for battle

UCSF scientists have discovered the unexpected way in which a key cell of the immune system prepares for battle. The finding, they said, offers insight into the processes that take place within these cells and could lead to strategies for treating conditions from spinal cord injury to cancer.

20 Jan 2012

Upper GI bleeding causes serious health problems in patients with kidney failure

Bleeding in the upper gastrointestinal (GI) tract causes serious health problems—and even early deaths—for many patients with kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

20 Jan 2012

CHORI senior scientist reveals mechanism for iron absorption from non-meat sources

A groundbreaking study conducted by Children's Hospital Oakland Research Institute (CHORI) Senior Scientist Elizabeth Theil, PhD, is the first to reveal the existence of at least two independent mechanisms for iron absorption from non-meat sources-and a potential treatment for iron deficiency, the most common nutrient deficiency worldwide.

20 Jan 2012

RHBDF2 gene plays a key role in growth of oesophageal cancer

New research from Queen Mary, University of London has uncovered a gene which plays a key role in the development of oesophageal cancer.

20 Jan 2012

New biomarkers can predict risk of kidney failure in patients with diabetes

Scientists at Joslin Diabetes Center have identified two novel markers that, when elevated in the blood stream, can predict accurately the risk of renal (kidney) failure in patients with Type 1 and Type 2 diabetes.

20 Jan 2012

Inflammation enhances pancreatic cancer cell progression

Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology at the Perelman School of Medicine, University of Pennsylvania, and Andrew Rhim, MD, a Gastroenterology Fellow in the Stanger lab, discovered that pancreatic cancer cells in an animal model begin to spread before clinically obvious tumor tissue is detected.

20 Jan 2012

First lady praises academic institutions for dedication to America's warriors

As part of a White House effort to ensure that America's military heroes receive care worthy of their service, the UCLA Health System and the David Geffen School of Medicine at UCLA have pledged to mobilize their uniquely integrated missions in education, research and clinical care to help train physicians to meet the special needs of veterans, active service members and their families.

20 Jan 2012

EMA CHMP may issue an opinion on CTI's Pixuvri MAA in mid-Feb.

Cell Therapeutics, Inc. ("CTI") announced today that, following discussions with the European Medicines Agency's ("EMA") Committee for Medicinal Products for Human Use ("CHMP"), the CHMP may issue an opinion on CTI's Marketing Authorization Application ("MAA") for Pixuvri in mid-February.

20 Jan 2012

About half of eligible and due services are missed during PHEs

More than 20 percent of U.S. adults receive periodic health examinations (PHE) each year, yet new research shows that patients who have an annual routine visit to their doctor may not receive recommended preventive screening tests and counseling services that could benefit their health.

20 Jan 2012

Study aims to help adult men and women with SAD

If winter's long nights and cold weather have you feeling depressed, a new research study could lift your spirits. The study, lead by Janis Anderson, PH.D., an associate psychologist in the Brigham and Women's Hospital Department of Psychiatry, aims to help adult (ages 21-64) men and women with Seasonal Affective Disorder (SAD) by comparing two new types of light technologies to determine which one works better.

20 Jan 2012