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Therakos commences enrollment in photopheresis Phase IIb clinical study for chronic GvHD

Therakos, Inc., a pioneer in the innovative treatment of extracorporeal photopheresis (ECP) for immune modulation therapy, today announced that the first patient has been enrolled in its Phase IIb clinical study evaluating the use of the company's photopheresis technology in the treatment of patients with moderate-to-severe chronic Graft-versus-Host Disease (GvHD).

6 Dec 2011

Positive final results from BioLineRx BL-1021 Phase Ia study for neuropathic pain

BioLineRx announced today the final results of the Phase Ia study of BL-1021, an orally available small molecule for neuropathic pain.

6 Dec 2011

PDUFA goal date of NDA for Protalix's taliglucerase alfa extended

Protalix BioTherapeutics, Inc., announced today that it received notification from the U.S. Food and Drug Administration (FDA) that the FDA has extended the Prescription Drug User Fee Act (PDUFA) goal date of the New Drug Application (NDA) for taliglucerase alfa to May 1, 2012, a three-month extension from the previous PDUFA date of February 1, 2012.

6 Dec 2011

Alzheimer's Australia, Bupa Health launch brain health app in the UK

The Bupa Health Foundation and Alzheimer's Australia have announced the UK launch of a world-first brain health app, the latest digital tool to help in the fight against dementia.

6 Dec 2011

Biosensors can detect oxidant production in living organism

Arterial calcification and coronary heart disease, neurodegenerative diseases such as Parkinson's and Alzheimer's, cancer and even the aging process itself are suspected to be partially caused or accelerated by oxidative stress. Oxidative stress arises in tissues when there is an excess of what are called reactive oxygen species.

6 Dec 2011

Experts to explore neuroethics of memory at SUNY Downstate symposium

Recent advances in understanding how memory functions and how memories could potentially be erased medically have raised numerous ethical questions. Scientists, ethicists, and legal scholars will explore the neuroethics of memory at a symposium organized by SUNY Downstate Medical Center on Friday, December 9, at the SUNY Global Center, 116 East 55th Street, New York, New York.

6 Dec 2011

Premature kids more likely to have behavioural/emotional problems

Children born just a few weeks too early are significantly more likely to have behavioural and/or emotional problems in the pre-school years, suggests research published online in the Archives of Disease in Childhood.

6 Dec 2011

Transient absorption tracks carbon nanotubes in living cells and bloodstream

Researchers have demonstrated a new imaging tool for tracking structures called carbon nanotubes in living cells and the bloodstream, which could aid efforts to perfect their use in biomedical research and clinical medicine.

6 Dec 2011

GE Healthcare, UCSF collaborate for cord blood project

UCSF and the Cell Technologies business of GE Healthcare Life Sciences have begun a unique collaboration aimed at overcoming the lack of blood-forming stem cells available to patients suffering from life-threatening diseases such as lymphoma, myeloma, leukemia or sickle cell anemia.

6 Dec 2011

Researchers reveal how podocytes may regenerate themselves during normal kidney function

Damage to podocytes -- a specialized type of epithelial cell in the kidney -- occurs in more than 90 percent of all chronic kidney disease. Now researchers at the Stanford University School of Medicine have uncovered an unexpected pathway that reveals for the first time how these cells may regenerate and renew themselves during normal kidney function.

6 Dec 2011

Researchers identify brain area that controls voluntary movement after damage

Researchers have identified the area of the brain that controls our ability to correct our movement after we've been hit or bumped -- a finding that may have implications for understanding why subjects with stroke often have severe difficulties moving.

6 Dec 2011

Exposure to family violence may increase brain activity in children

Children exposed to family violence show the same pattern of activity in their brains as soldiers exposed to combat, new research has shown.

6 Dec 2011

Epilepsy in children with ASD is photosensitive: Study

Epilepsy is common in children with autism spectrum disorders (ASD). A new study indicates their epilepsy is surprisingly photosensitive as well. Since photosensitive epilepsies can be triggered by flickering lights, the self-stimulatory behavior of ASD children, such as hand flapping in front of the face, has the potential to dramatically increase the risk of inducing photosensitive seizures.

6 Dec 2011

Study identifies ways to differentiate types of diabetes in young Asian Americans

Researchers at Joslin Diabetes Center have determined key differences between Type 1 and Type 2 diabetes in the Asian American population. This study, published today in PLoS ONE, identified ways to differentiate the types of diabetes, which can be clinically similar in young Asian Americans.

6 Dec 2011

Autism linked with disorganized structure of brain's white matter

It's still unclear what's different in the brains of people with autism spectrum disorders (ASDs), but evidence from genetic and cell studies points to abnormalities in how brain cells (neurons) connect to each other. A study at Children's Hospital Boston now provides visual evidence associating autism with a disorganized structure of brain connections, as well as defects in myelin -- the fatty, insulating coating that helps nerve fibers conduct signals and that makes up the brain's white matter.

6 Dec 2011

MHI cardiologists use ABSORB bioresorbable vascular scaffold to treat CAD

The interventional cardiology team at the Montreal Heart Institute (MHI) used the world's first drug eluting bioresorbable vascular scaffold to successfully treat a woman suffering from coronary artery disease. This landmark procedure was performed by Dr. Jean-Fran-ois Tanguay, interventional cardiologist and coordinator of the Coronary Unit, as part of the ABSORB EXTEND clinical trial.

6 Dec 2011

FDA assigns CTIs' pixantrone NDA new PDUFA action date

Cell Therapeutics, Inc. today announced that the U.S. Food and Drug Administration's Division of Oncology Products 1 has notified CTI that CTI's October 2011 resubmitted New Drug Application is considered a complete, Class 2 response to the FDA's April 2010 complete response letter.

6 Dec 2011

Telemedicine can improve depression in nursing home rehab patients

A new pilot study is getting underway in Rhode Island aimed at improving depression in nursing home rehabilitation patients, all through telemedicine. Geriatric mental health specialists from Rhode Island and The Miriam hospitals will work with patients in the Evergreen House Nursing Home and Rehabilitation Center in East Providence to test the program.

6 Dec 2011

Study reveals mechanism of action of laquinimod in patients with RRMS

Laquinimod is an orally available synthetic compound that has been successfully evaluated in phase II/III clinical studies for the treatment of relapsing-remitting multiple sclerosis (RRMS).

6 Dec 2011

Fetal exposure to valproate impairs IQ till age six

Researchers in the U.S. and U.K. are conducting an ongoing investigation of the cognitive effect of fetal exposure across four commonly used antiepileptic drugs (AEDs) as part of an NIH-funded Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) Study. An early NEAD analysis found that fetal exposure to valproate impairs IQ at age three.

6 Dec 2011