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ARPP21 gene mutation could be the cause of ALS

Researchers from the Neuromuscular Diseases Group and the Dementia Neurobiology Group of the Sant Pau Research Institute (IR Sant Pau) and the Memory Unit of the Sant Pau Hospital, led by neurologist Dr. Ricard Rojas-García, have identified a new mutation in the ARPP21 gene that could be the cause of Amyotrophic Lateral Sclerosis (ALS), a devastating neurodegenerative disease.

11 Jul 2024

Light-activated drugs: A revolutionary approach in neuropathic pain treatment

Light can be used to activate drugs in specific parts of the body through photopharmacology.

11 Jul 2024

Unveiling late-onset combined immunodeficiency in patients with 18q del syndrome

Chromosome 18q deletion (18q del) syndromeis a rare genetic condition disorder, affecting approximately 1 in 40,000 to 55,000 individuals, caused by the deletion of genetic material on the long arm of chromosome 18.

11 Jul 2024

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.

11 Jul 2024

Study: 40% of cancer cases in the U.S. attributable to modifiable risk factors

A new study led by researchers at the American Cancer Society (ACS) finds four in 10 cancer cases and about one-half of all cancer deaths in adults 30 years old and older in the United States (or 713,340 cancer cases and 262,120 cancer deaths in 2019) could be attributed to modifiable risk factors, including cigarette smoking, excess body weight, alcohol consumption, physical inactivity, diet, and infections.

11 Jul 2024

New study reveals the genetic cause of Parkinson's disease

According to Science Alert, neuroscientists from Johns Hopkins University have recently discovered a new treatment for Parkinson's disease using an FDA-approved cancer drug.

11 Jul 2024

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy treatments.

11 Jul 2024

Prime editing offers promising path to permanent treatment for cystic fibrosis

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection.

11 Jul 2024

Novel model could predict cognitive decline in patients with mild cognitive impairment due to Alzheimer's

Amsterdam UMC's Alzheimer Centre has developed a prediction model that can predict cognitive decline in patients with mild cognitive impairment or mild dementia due to Alzheimer's disease.

11 Jul 2024

Novel Co-STAR cells show promise in targeting and eradicating cancer

Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center, the Lustgarten Laboratory and Bloomberg~Kimmel Institute for Cancer Immunotherapy have designed a novel type of cell to recognize and fight cancer.

11 Jul 2024

Poverty and mental Illness: A causal relationship revealed

Poverty and mental illness are not only linked, but there is also a causal relationship. This is the conclusion of researchers from Amsterdam UMC, the University of Edinburgh and the University of Modena.

11 Jul 2024

Machine-learning model can predict survival of dialysis patients on Continuous Renal Replacement Therapy

A UCLA-led team has developed a machine-learning model that can predict with a high degree of accuracy the short-term survival of dialysis patients on Continuous Renal Replacement Therapy (CRRT).

11 Jul 2024

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

A study led by the Hospital del Mar Research Institute, with Cima University of Navarra and Pompeu Fabra University, has identified a group of small molecules exclusive to liver tumors that could be key to developing cancer vaccines.

11 Jul 2024

Innovative aiTBS therapy shortens treatment duration for bipolar disorder

A potential new treatment for bipolar disorder (BP) that significantly shortens treatment time has emerged, following a randomized clinical trial using accelerated intermittent theta burst stimulation (aiTBS).

11 Jul 2024

LSVT LOUD outperforms NHS speech and language therapy for people with Parkinson's disease

An intensive voice treatment developed in the USA and known as the Lee Silverman voice treatment (LSVT LOUD) is more effective than conventional NHS speech and language therapy or no therapy for people with Parkinson's disease, finds a trial published in The BMJ today.

11 Jul 2024

Medical Condition News

ARPP21 gene mutation could be the cause of ALS

Light-activated drugs: A revolutionary approach in neuropathic pain treatment

Unveiling late-onset combined immunodeficiency in patients with 18q del syndrome

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Study: 40% of cancer cases in the U.S. attributable to modifiable risk factors

New study reveals the genetic cause of Parkinson's disease

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

Prime editing offers promising path to permanent treatment for cystic fibrosis

Novel model could predict cognitive decline in patients with mild cognitive impairment due to Alzheimer's

Novel Co-STAR cells show promise in targeting and eradicating cancer

Poverty and mental Illness: A causal relationship revealed

Machine-learning model can predict survival of dialysis patients on Continuous Renal Replacement Therapy

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

Innovative aiTBS therapy shortens treatment duration for bipolar disorder

LSVT LOUD outperforms NHS speech and language therapy for people with Parkinson's disease

AI model accurately estimates pulmonary function from chest x-rays

Archaeal, fungal, viral, as well as bacterial, functional makers for autism spectrum disorder in children

How did hospitalizations for mental health conditions in children change following the COVID-19 pandemic?

Gut bacteria-metabolized equol shows promise in cancer prevention

Study finds disparities in heart bypass surgery for women

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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