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Air pollution: a pressing global health crisis demanding urgent interdisciplinary action

The research highlights the severe health impacts of air pollution and underscores the urgent need for interdisciplinary research and evidence-based interventions to mitigate these effects, particularly in vulnerable populations and low- and middle-income countries.

28 Jul 2024

Cytomegalovirus in breast milk linked to changes in infant growth and gut microbiome

Research shows human cytomegalovirus (CMV) reactivation in breast milk affects milk composition, infant gut microbiome, and growth, with potential impacts on neonatal health.

28 Jul 2024

Machine learning revolutionizes Parkinson's disease symptom tracking and progression prediction

Research develops an automated system using machine learning to quantify motor symptoms in Parkinson's disease and predict disease progression, offering new therapeutic insights.

28 Jul 2024

Study finds genetic factors key to post-stroke cardiovascular risks

Research identifies genetic and molecular risk factors for cardiovascular outcomes after an initial stroke, uncovering potential therapeutic targets to improve patient prognoses.

28 Jul 2024

Study finds body composition impacts neurodegenerative disease risk

Research reveals body composition patterns can influence the risk of neurodegenerative diseases, with certain patterns linked to increased risk due to cardiovascular disease.

28 Jul 2024

Scientists explore early life factors contributing to SMA

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists at DZNE and the Dresden University of Technology are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies of so-called organoids: Laboratory-grown tissue cultures that can reconstruct disease processes. Their findings are published in the journal Cell Reports Medicine.

27 Jul 2024

Breakthrough therapy heals spinal cord injuries

In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving "dancing molecules," to repair tissues and reverse paralysis after severe spinal cord injuries.

27 Jul 2024

Innovative dual-drug strategy for colorectal cancer treatment

A combination of two drugs was capable of suppressing tumors in a non-conventional manner. Instead of inhibiting tumor cell division, as the most widely used medications do, the strategy consisted of hyperactivating oncogenic signaling by these cells to the point where they became stressed.

27 Jul 2024

New biomarker helps determine the optimal treatment for colon cancer

Many people with stage II or III colon cancer receive additional, or adjuvant, chemotherapy following surgery. However, clinical trials have shown that this treatment doesn't improve the chances of survival for every patient. A study published July 25th, 2024 in Cell Reports Medicine identifies and validates a 10-gene biomarker that potentially predicts whether a stage II or III colon cancer patient will benefit from adjuvant chemotherapy.

27 Jul 2024

New study highlights paternal influence on child's T1D risk

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) (Madrid, 9-13 September) shows that a child is almost twice as likely to develop type 1 diabetes (T1D) if their father has the condition than if their mother has the condition.

27 Jul 2024

New guidelines expand BRCA testing and screening for men

More and more studies show that men face risks of cancer from BRCA1 and BRCA2 genetic mutations that are most often associated with breast and ovarian cancers in women.

27 Jul 2024

Study finds stark differences in stroke center access by income

Low-income communities are up to 42% less likely to obtain stroke center certification.

27 Jul 2024

Moffitt study identifies predictive biomarkers for immunotherapy in merkel cell carcinoma

Merkel cell carcinoma is a rare but highly aggressive form of skin cancer known for its rapid growth and tendency to metastasize. Despite the promise of immune checkpoint blockade therapy, which can boost the body's immune response against cancer cells, nearly half of patients do not respond to this treatment.

26 Jul 2024

UCLA scientists awarded $300,000 grant to study glioblastoma microenvironment

Scientist Dr. Aparna Bhaduri, assistant professor of medicine and biological chemistry, and neurosurgeon Dr. Kunal Patel, assistant professor of neurosurgery, both part of the UCLA Health Jonsson Comprehensive Cancer Center, have received the 2024 Neurobiology of Brain Disorders Award from the McKnight Endowment Fund for Neuroscience, which supports innovative research by U.S. scientists who are studying neurological and psychiatric diseases.

26 Jul 2024

Anxiety’s Long-Term Impact on Dementia Development

The longitudinal relationship between chronic, resolved, and new onset anxiety and the risk of all-cause dementia (Progressive cognitive decline affecting memory and thinking).

26 Jul 2024

Machine learning models predict disability progression in multiple sclerosis

Machine learning models can reliably inform clinicians about the disability progression of multiple sclerosis, according to a new study published this week in the open-access journal PLOS Digital Health by Edward De Brouwer of KU Leuven, Belgium, and colleagues.

25 Jul 2024

Cordyceps sinensis shown to alleviate idiopathic pulmonary fibrosis in mice

A recent study from China has reported that Cordyceps sinensis (CS), a traditional Chinese medicinal fungus, can ameliorate idiopathic pulmonary fibrosis (IPF) in mice by inhibiting mitochondrion-mediated oxidative stress.

25 Jul 2024

Medicaid policies boost oncology clinical trial enrollment for Black and Hispanic patients

Two Medicaid policies can interact to increase oncology clinical trial enrollment among Black and Hispanic patients, according to a new study by investigators at Weill Cornell Medicine, the University of Pennsylvania, and Medidata AI.

25 Jul 2024

Researchers identify a potential therapeutic target for advanced multiple sclerosis

Researchers from Kyushu University have identified a potential therapeutic target for the treatment of advanced multiple sclerosis (MS), a potentially disabling condition associated with the central nervous system.

25 Jul 2024

New review highlights advances in diabetes research and treatment

A new paper surveying advances in diabetes pathogenesis and treatment explores the complex factors contributing to the onset and progression of the disease, suggesting that an understanding of these dynamics is key to developing targeted interventions to reduce the risk of developing diabetes and managing its complications.

25 Jul 2024