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Recombinant shingles vaccination found to lower dementia risk

The effects of recombinant shingles vaccines on dementia.

25 Jul 2024

Racial, ethnic, and socioeconomic differences in air pollution-related deaths in the United States

Disparities in mortality rates by ethnicity, race, educational attainment, social vulnerability, and rurality, ascribed to differences in susceptibility and exposure to particulate matter up to 2.5 millimeters in diameter (PM2.5).

25 Jul 2024

Study reveals moderate burden of post-COVID conditions in primary care

The post-COVID-19 conditions (PCC) or long COVID prevalence among United States (US) adults infected with SARS-CoV-2.

25 Jul 2024

Study highlights infection as major post-CAR-T therapy challenge

In patients with diffuse large B-cell non-Hodgkin lymphoma (DLBCL), the two hallmark post-chimeric antigen receptor (CAR)-T therapy toxicities are extremely rare after two weeks, supporting a shorter, more flexible toxicity monitoring period, according to a study published in Blood Advances.

25 Jul 2024

Unprecedented brain cell mapping sheds light on Alzheimer's

Less than a decade ago, when Dr. Hansruedi Mathys launched an ambitious project to create an annotated library of all the gene readouts stored within 100 individual brain cells, the task felt daunting.

25 Jul 2024

Tiny titin mutation linked to developmental heart defects and adult atrial fibrillation

Millions of adults have atrial fibrillation - an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.

25 Jul 2024

Comprehensive analysis of Alzheimer’s brain tissue identifies novel biomarkers

From studying the human genome, to analyzing the way proteins are encoded, or monitoring RNA expression, researchers are rapidly gaining a far richer understanding of the complex genetic and cellular mechanisms that underpin dementia. But there's a catch: While new technologies are revealing myriad avenues for Alzheimer's research, it's impossible to know in advance which research pathways will lead to effective treatments.

25 Jul 2024

New insights into p16 protein could lead to advances in cancer diagnosis and treatment

Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis of various cancers.

25 Jul 2024

Gene variant predicts cognitive decline after stroke

New research led by UCLA Health has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

25 Jul 2024

Pesticide use in agriculture may pose cancer risks similar to smoking

In modern day agriculture, pesticides are essential to ensure high enough crop yields and food security.

25 Jul 2024

Study confirms esaxerenone as a safe and effective alternative for hypertension treatment

Researchers find that esaxerenone is a non-inferior alternative to trichlormethiazide for treating uncontrolled hypertension in Japanese patients. The study confirms similar safety profiles for both drugs.

25 Jul 2024

Opioid use disorder medications underused after injection-related infections

Deaths from injection-related infections like endocarditis have increased among young people, likely due to the growth of injection drug use and stronger, shorter-acting fentanyl.

24 Jul 2024

Cognitive decline persists in older adults long after severe COVID-19 recovery

Older adults recovering from COVID-19 experience varying degrees of cognitive decline over 2.5 years, with severe cases showing the most significant impact. Early cognitive care and monitoring are crucial for improving outcomes.

24 Jul 2024

Wearable devices can amplify anxiety in people with Afib

Using a wearable device, such as a smart watch, to track health data and symptoms, is supposed to help people monitor their health and address symptoms as quickly as possible to spur positive health outcomes.

24 Jul 2024

Retinoblastoma therapy evolves with higher success rates and lower complications

The evolution of retinoblastoma treatment over the past 15 years has resulted in a higher likelihood of vision preservation without compromising survival, according to research released today at the Society of NeuroInterventional Surgery's (SNIS) 21st Annual Meeting.

24 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

24 Jul 2024

High belly and arm fat linked to Alzheimer's and Parkinson's risk

People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to a study published in the July 24, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

24 Jul 2024

Breakthrough in acute myeloid leukemia treatment targets stem cells

Acute myeloid leukemia is one of the deadliest cancers. Leukemic stem cells responsible for the disease are highly resistant to treatment.

24 Jul 2024

Simple blood test may predict CAR-T therapy success in multiple myeloma

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research from Weill Cornell Medicine, NewYork-Presbyterian, Columbia University and Icahn School of Medicine at Mount Sinai.

24 Jul 2024