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Cancer genomes: Distinguishing between 'driver' and 'passenger' mutations

A new study of mutations in cancer genomes shows how researchers can begin to distinguish the 'driver' mutations that push cells towards cancer from the 'passenger' mutations that are a by-product of cancer cell development. The study also shows that at least one in nine genes can be removed without killing human cells.

19 Feb 2010

Mental health care for federally incarcerated offenders through telemedicine

A bold new initiative soon to be implemented in federal prisons in Ontario will help to address the treatment needs for federal offenders with mental health issues.

19 Feb 2010

United Therapeutics announces withdrawal of Tyvaso European MAA for treatment of PAH

United Therapeutics Corporation announced today that it has withdrawn its Marketing Authorization Application (MAA) for Tyvaso (treprostinil sodium) 0.6 mg/ml nebuliser solution for the treatment of pulmonary arterial hypertension (PAH) in the European Union.

19 Feb 2010

Depomed receives final meeting minutes from FDA for pre-NDA meeting on DM-1796 for PHN

Depomed, Inc. today announced that it has received final meeting minutes from the FDA for a pre-NDA meeting related to DM-1796 for postherpetic neuralgia (PHN) held in December 2009. Depomed also commented on recent public disclosures related to the Complete Response letter from the U.S. Food and Drug Administration regarding the New Drug Application (NDA) for Horizant™ (gabapentin enacarbil) Extended-Release Tablets.

19 Feb 2010

Most genetic abnormalities shared across multiple cancers

An international team of researchers has created a genome-scale map of 26 different cancers, revealing more than 100 genomic sites where DNA from tumors is either missing or abnormally duplicated compared to normal tissues. The study, the largest of its kind, finds that most of these genetic abnormalities are not unique to one form of cancer, but are shared across multiple cancers. The work appears in the February 18 issue of the journal Nature.

19 Feb 2010

University of California researchers awarded AAN's 2010 Potamkin Prize

The American Academy of Neurology (AAN) is awarding its 2010 Potamkin Prize to two researchers for their work in Alzheimer's disease and frontotemporal lobar degeneration (FTLD), a common type of dementia. Bruce L. Miller, MD, and Lennart Mucke, MD, both of the University of California San Francisco will receive the Award during the AAN's 62nd Annual Meeting in Toronto, April 10 - 17, 2010. The AAN Annual Meeting is the world's largest gathering of neurologists with more than 2,000 presentations made on the latest advances in neurologic research.

19 Feb 2010

Contrast-enhanced MRI may help physicians differentiate between rheumatoid and psoriatic arthritis

Contrast-enhanced magnetic resonance imaging (MRI) may help physicians differentiate between rheumatoid arthritis and psoriatic arthritis in the hand and wrist enabling more targeted therapies unique to each condition, according to a study in the March issue of the American Journal of Roentgenology. Contrast-enhanced MRI uses contrast media to improve the visibility of internal bodily structures.

19 Feb 2010

Roseville ROC commences cancer treatment with Elekta VMAT

The first treatments with Elekta Volumetric Modulated Arc Therapy (VMAT) began November 17, 2009 at Roseville Radiation Oncology Center (ROC) at Radiological Associates of Sacramento (RAS). RAS, a large private medical group, includes diagnostics as well as therapy in its centers. ROC treats 30-35 patients per day, mainly with prostate and breast lesions.

From Elekta 19 Feb 2010

Most important osteoporosis meeting of 2010: More than 850 abstracts received

More than 850 abstracts have been received - guaranteeing broad global attendance at the year's most noteworthy platform for osteoporosis research. Don't miss the most important osteoporosis meeting of 2010, to be held in the center of Florence, Italy from May 5 to 8, 2010.

19 Feb 2010

AGH neurosurgeons explore new therapeutic approach for brain tumor

Neurosurgeons at Allegheny General Hospital (AGH) are exploring use of a drug that illuminates brain tumor cells to determine if the experimental visualization technique will enhance their ability to surgically excise tumors and improve patient survival.

19 Feb 2010

Researchers use Life Technologies’ next-generation sequencing instruments for cancer research

Life Technologies Corporation today announced the publication of two key scientific papers that highlight the utility of next-generation sequencing instruments in better understanding disease and the genetic differences that cause diversity within and between human populations. The Applied Biosystems SOLiD™ System was used in both of these research studies.

19 Feb 2010

FDA approves 53 new cancer indications between July 2005 and end of 2007

The U.S. Food and Drug Administration's Office of Oncology Drug Products approved more than 50 new indications for the use of oncology and hematology drugs and biologics between July 2005, when the office began reviewing marketing applications, and the end of 2007, according to a new agency study.

19 Feb 2010

Research shows natural compound in marine sponges reduces cancer cell motility

Investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham, formerly Burnham Institute for Medical Research) led by Kristiina Vuori, M.D., Ph.D., have discovered that the natural compound sceptrin, which is found in marine sponges, reduces cancer cell motility (movement) and has very low toxicity.

19 Feb 2010

ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy

ATM, a protein that reacts to DNA damage by ordering repairs or the suicide of the defective cell, plays a similar, previously unknown role in response to oxidative damage outside of the nucleus, researchers report this week in the online version of the Proceedings of the National Academy of Sciences.

19 Feb 2010

Novartis' Tasigna capsules granted priority review by FDA for treatment of adult patients with Ph+ CML

Novartis announced today that Tasigna® (nilotinib) 200 mg capsules has been granted priority review by the US Food and Drug Administration for the treatment of adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase.

19 Feb 2010

Untreated gum disease has potentially dangerous implications

The American Academy of Periodontology (AAP) estimates that approximately three out of four Americans suffer from some form of gum disease -- from mild cases of gingivitis, to the more severe form known as periodontitis. However, despite this prevalence, approximately only three percent seek treatment for their gum disease. With increasingly more research indicating that gum disease may be linked to several other diseases, including diabetes, heart disease and certain forms of cancer, maintaining healthy teeth and gums has become more important that ever.

19 Feb 2010

NBCH's annual report: How America's health plans are doing to improve care and control costs for diabetes

Today the National Business Coalition on Health issued its annual report on how America's health plans are doing to improve care and control costs for diabetes. The analysis is based on health plan survey data from NBCH's eValue8™ program, the nation's leading Request for Information (RFI) tool used by employers, coalitions and their purchaser members to set expectations and measure health plan performance.

19 Feb 2010

Medical experts craft much-needed classification system for diabetic nephropathy

An international group of medical experts has crafted a much-needed classification system for diabetic nephropathy, the leading cause of total kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The effort should improve communication among health professionals, help researchers design better clinical studies, and guide patient care.

19 Feb 2010

New endoscopic ablation technique safe and effective for treating Barrett's esophagus

Early tumor formation in Barrett's esophagus (BE) can be effectively and safely treated with radiofrequency ablation (RFA), in combination with prior endoscopic removal of visible lesions, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.

19 Feb 2010

Lucile Packard Children’s Hospital gearing up for National Eating Disorders Awareness Week

Lucile Packard Children’s Hospital at Stanford is gearing up for National Eating Disorders Awareness Week, Feb. 21 – 27. The hospital's Comprehensive Eating Disorders Program is reaching out to Bay Area families to enhance knowledge of anorexia nervosa, bulimia nervosa and related diagnoses.

19 Feb 2010

Medical Condition News

Cancer genomes: Distinguishing between 'driver' and 'passenger' mutations

Mental health care for federally incarcerated offenders through telemedicine

United Therapeutics announces withdrawal of Tyvaso European MAA for treatment of PAH

Depomed receives final meeting minutes from FDA for pre-NDA meeting on DM-1796 for PHN

Most genetic abnormalities shared across multiple cancers

University of California researchers awarded AAN's 2010 Potamkin Prize

Contrast-enhanced MRI may help physicians differentiate between rheumatoid and psoriatic arthritis

Roseville ROC commences cancer treatment with Elekta VMAT

Most important osteoporosis meeting of 2010: More than 850 abstracts received

AGH neurosurgeons explore new therapeutic approach for brain tumor

Researchers use Life Technologies’ next-generation sequencing instruments for cancer research

FDA approves 53 new cancer indications between July 2005 and end of 2007

Research shows natural compound in marine sponges reduces cancer cell motility

ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy

Novartis' Tasigna capsules granted priority review by FDA for treatment of adult patients with Ph+ CML

Untreated gum disease has potentially dangerous implications

NBCH's annual report: How America's health plans are doing to improve care and control costs for diabetes

Medical experts craft much-needed classification system for diabetic nephropathy

New endoscopic ablation technique safe and effective for treating Barrett's esophagus

Lucile Packard Children’s Hospital gearing up for National Eating Disorders Awareness Week

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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