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OCT-guided PCI does not reduce target vessel failure in complex patients, but improves safety

Optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) leads to a larger minimum stent area but does not reduce the two-year rate of target vessel failure compared with angiography-guided PCI, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

University of Michigan researchers have discovered that the same cellular mechanism involved in a form of cystic fibrosis is also implicated in a form of a rare disease called cystinosis.

28 Aug 2023

Eating your way out of pain: How your gut microbiota and diet can help manage chronic discomfort

A recent study in the Nutrients journal employs bibliometrics to explore how nutrition impacts the relationship between gut microbiota and chronic pain. The research highlights the potential of probiotics and prebiotics in managing pain conditions and underscores the need for further studies to understand the interplay between diet, gut health, and chronic pain.

28 Aug 2023

Study highlights the economic burden of cardiovascular diseases in the European Union

Cardiovascular disease (CVD) cost the EU an estimated €282 billion in 2021, according to late breaking research presented at ESC Congress 2023.

28 Aug 2023

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Researchers explore how lifestyle changes like diet and physical activity can influence microRNA expression in Alzheimer's patients, potentially offering new therapeutic avenues. The study fills a research gap in understanding how such lifestyle modifications could affect molecular mechanisms implicated in Alzheimer’s disease.

28 Aug 2023

Trial addresses the optimal timing for complete revascularization of patients with STEMI and multivessel disease

Immediate multivessel percutaneous coronary intervention (PCI) is non-inferior to staged multivessel PCI for reducing death and ischaemic events in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Scientific breakthrough could someday save the lives of children with rhabdomyosarcoma

"Every successful medicine has its origin story. And research like this is the soil from which new drugs are born," says Cold Spring Harbor Laboratory Professor Christopher Vakoc.

28 Aug 2023

ECLS does not improve survival in patients with acute myocardial infarction complicated by cardiogenic shock

Early extracorporeal life support (ECLS) does not improve survival in patients with acute myocardial infarction complicated by cardiogenic shock who are scheduled for early revascularization, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Pulsed field ablation safe, effective for the treatment of paroxysmal atrial fibrillation

Pulsed field ablation (PFA) is as effective and safe as conventional thermal ablation for the treatment of paroxysmal atrial fibrillation (AF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Study shows efficacy and safety of OCT-guided strategy for percutaneous coronary intervention

Optical coherence tomography (OCT) is non-inferior to intravascular ultrasound (IVUS) for guiding percutaneous coronary intervention (PCI), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Acoramidis shows potential to be effective, safe treatment for transthyretin amyloid cardiomyopathy

Acoramidis improves outcomes in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Switching to NOACs in frail elderly patients with atrial fibrillation increases bleeding risk

Switching vitamin K antagonist (VKA) treatment to a non-vitamin K antagonist oral anticoagulant (NOAC) in frail elderly patients with atrial fibrillation is associated with more bleeding complications compared to continuing VKA treatment.

28 Aug 2023

Intravascular imaging-guided PCI associated with lower rate of target lesion failure

Intravascular imaging-guided percutaneous coronary intervention (PCI) is associated with a lower rate of target lesion failure compared with angiography-guided PCI, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Ablation more effective than medical therapy in patients with end-stage heart failure, study shows

Atrial fibrillation ablation is associated with lower rates of death, urgent heart transplantation or left ventricular assist device (LVAD) implantation compared with medical therapy in patients with end-stage heart failure, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Physiology-guided complete revascularization reduces ischemic events in older MI patients

Physiology-guided complete revascularization reduces ischemic events compared with culprit-only revascularization in myocardial (MI) infarction patients aged 75 years or older with multivessel disease, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

ARREST trial results question need to transport all cardiac arrest patients to centers

A randomized trial involving all hospitals in London, UK, has found no difference in survival at 30 days in patients with resuscitated cardiac arrest in the community who were taken by ambulance to a cardiac arrest center compared with those delivered to the geographically closest emergency department.

28 Aug 2023

First oral treatment for Lipoprotein(a) shows significant cholesterol reduction

A new drug offers a breakthrough world first treatment for Lipoprotein(a), a largely genetic form of cholesterol that increases the risk of heart attack and stroke, announced today by study lead Professor Stephen Nicholls, Director of the Monash University's Victorian Heart Institute and Victorian Heart Hospital.

28 Aug 2023

Study confirms the anti-cancer effects of Kencur extract

You may know it as an aromatic spice to add flavor to your dishes or as a soothing herbal remedy to use for upset stomachs, but researchers from Osaka Metropolitan University have uncovered promising findings that Kencur, a tropical plant in the ginger family native to Southeast Asia, possesses anti-cancer effects.

28 Aug 2023

Obese adults with ARDS may benefit from ECMO

A National Institutes of Health-supported study suggests that adults with obesity may benefit from the use of extracorporeal membrane oxygenation (ECMO), an advanced form of breathing support, when in intensive care for respiratory failure.

28 Aug 2023

Dual-antiplatelet therapy should remain the standard strategy for PCI even in the drug-eluting stent era

Prasugrel monotherapy after percutaneous coronary intervention (PCI) with drug-eluting stents is not superior to dual-antiplatelet therapy (DAPT) for major bleeding but is non-inferior for cardiovascular events in patients with acute coronary syndrome (ACS) or high bleeding risk (HBR), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Medical Condition News

OCT-guided PCI does not reduce target vessel failure in complex patients, but improves safety

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

Eating your way out of pain: How your gut microbiota and diet can help manage chronic discomfort

Study highlights the economic burden of cardiovascular diseases in the European Union

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Trial addresses the optimal timing for complete revascularization of patients with STEMI and multivessel disease

Scientific breakthrough could someday save the lives of children with rhabdomyosarcoma

ECLS does not improve survival in patients with acute myocardial infarction complicated by cardiogenic shock

Pulsed field ablation safe, effective for the treatment of paroxysmal atrial fibrillation

Study shows efficacy and safety of OCT-guided strategy for percutaneous coronary intervention

Acoramidis shows potential to be effective, safe treatment for transthyretin amyloid cardiomyopathy

Switching to NOACs in frail elderly patients with atrial fibrillation increases bleeding risk

Intravascular imaging-guided PCI associated with lower rate of target lesion failure

Ablation more effective than medical therapy in patients with end-stage heart failure, study shows

Physiology-guided complete revascularization reduces ischemic events in older MI patients

ARREST trial results question need to transport all cardiac arrest patients to centers

First oral treatment for Lipoprotein(a) shows significant cholesterol reduction

Study confirms the anti-cancer effects of Kencur extract

Obese adults with ARDS may benefit from ECMO

Dual-antiplatelet therapy should remain the standard strategy for PCI even in the drug-eluting stent era

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