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Adaptive platform trial shows promise for finding new glioblastoma therapies

An innovative phase 2 clinical trial led by Dana-Farber Cancer Institute in collaboration with 10 major brain tumor centers around the country and designed to find new potential treatments for glioblastoma has reported initial results in the Journal of Clinical Oncology. While none of the three therapeutics tested so far improved overall survival of patients, this adaptive platform trial, the first of its kind in neuro-oncology, has the potential to rapidly and efficiently identify therapies that benefit patients.

19 Sep 2023

Nano-based cancer therapies may be less effective in younger patients, finds study

Researchers at The University of Texas MD Anderson Cancer Center have discovered that certain nano-based cancer therapies may be less effective in younger patients, highlighting the need for further investigation into the impact of aging on the body's ability to respond to treatment.

19 Sep 2023

New study suggests higher buprenorphine doses could help save lives

Individuals with opioid use disorder who were prescribed a lower buprenorphine dose were 20% more likely to discontinue treatment than those on a higher dose, according to a study of patients prescribed buprenorphine in Rhode Island from 2016 to 2020, as fentanyl became widely available.

19 Sep 2023

New CAR T cell therapy approach minimizes severe side effects

In recent years, cancer researchers have hailed the arrival of chimeric antigen receptor T cell (CAR T) therapy, which has delivered promising results, transforming the fight against various forms of cancer. The process involves modifying patients' T-cells to target cancer cells, resulting in remarkable success rates for previously intractable forms of cancer.

19 Sep 2023

Analyzing development of improved child-resistant medication dispensing and tracking systems

Attention-deficit/hyperactivity disorder (ADHD) is among the most common pediatric neurodevelopmental disorders. In 2019, nearly 10% of United States (U.S.) children had a diagnosis of ADHD. Approximately 3.3 million children, or roughly 5 out of every 100 children in the U.S., are currently prescribed medication for ADHD.

19 Sep 2023

New tool may help identify inflammatory breast cancer quicker and at earlier stages

A new diagnostic scoring system, developed by renowned breast cancer experts, is now available as an easy-to-use online tool through Susan G. Komen®, the world's leading breast cancer organization.

19 Sep 2023

Gaining new insights into neurological diseases by studying circular RNAs in brain cells

Researchers are gaining new insights into neurological diseases by studying circular RNAs (circRNAs) in brain cells.

19 Sep 2023

New implantable device carries insulin-producing islet cells to control diabetes

One promising approach to treating Type 1 diabetes is implanting pancreatic islet cells that can produce insulin when needed, which can free patients from giving themselves frequent insulin injections.

19 Sep 2023

Uniink: A new 3D bioprinted cell therapy approach for Type 1 diabetes

Javier Ramón Azcón, an ICREA research professor and the leader of the Biosensors for Bioengineering group at the Institute for Bioengineering of Catalonia (IBEC), has been granted an "ERC Proof of Concept Grant."

18 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Researchers identify key mechanisms to address future treatments for hereditary blindness

There are still many enigmas about the mechanism of action of the CERKL gene, which causes retinitis pigmentosa and other hereditary vision diseases.

18 Sep 2023

Study highlights a promising therapy to mitigate spaceflight-induced bone loss

A new study published in a Nature Partner Journal, npj Microgravity, finds an engineered compound given to mice aboard the International Space Station (ISS) largely prevented the bone loss associated with time spent in space.

18 Sep 2023

New immunoregulatory protein linked to autoimmune disease

Autoimmune diseases are complex illnesses, the causes of which are diverse and have not yet been fully explained.

18 Sep 2023

Researchers conduct comprehensive psychological evaluation of university students

The prevalence rates of stress, depression, anxiety, insomnia, mania, suicidal ideation, loneliness, and psychotic experiences among university-going students in the UK.

18 Sep 2023

How important is inflammation and body weight in the origin of depression?

A new paper in BMC Medicine examines the role of inflammation and body mass index (BMI) in the etiology of treatment-resistant depression.

18 Sep 2023

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers develop CRISPR-human organoids-single-cell RNA sequencing system to identify developmental brain defects in autism.

18 Sep 2023

AI model for detecting ocular disease using retinal images

Researchers present RETFound, a self-supervised learning masked autoencoder-based foundation model for retinal images.

18 Sep 2023

Wireless molecular-electrical communications for tumor-cell-induced apoptosis

Researchers utilize electricity generated by wireless-induced redox interactions at bio-nanoantennae to cause apoptosis in cancerous cells.

18 Sep 2023

Physical therapy can help reduce risk of dizziness-induced injury

The association between symptomatic dizziness and vestibular disorders and the subsequent risk of falls and other injuries.

18 Sep 2023

AI in clinical practice: positive outcomes dominate but questions linger, study finds

The clinical relevance of AI.

18 Sep 2023

Medical Condition News

Adaptive platform trial shows promise for finding new glioblastoma therapies

Nano-based cancer therapies may be less effective in younger patients, finds study

New study suggests higher buprenorphine doses could help save lives

New CAR T cell therapy approach minimizes severe side effects

Analyzing development of improved child-resistant medication dispensing and tracking systems

New tool may help identify inflammatory breast cancer quicker and at earlier stages

Gaining new insights into neurological diseases by studying circular RNAs in brain cells

New implantable device carries insulin-producing islet cells to control diabetes

Uniink: A new 3D bioprinted cell therapy approach for Type 1 diabetes

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Researchers identify key mechanisms to address future treatments for hereditary blindness

Study highlights a promising therapy to mitigate spaceflight-induced bone loss

New immunoregulatory protein linked to autoimmune disease

Researchers conduct comprehensive psychological evaluation of university students

How important is inflammation and body weight in the origin of depression?

Single-cell screening of cerebral organoids to identify developmental defects in autism

AI model for detecting ocular disease using retinal images

Wireless molecular-electrical communications for tumor-cell-induced apoptosis

Physical therapy can help reduce risk of dizziness-induced injury

AI in clinical practice: positive outcomes dominate but questions linger, study finds

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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