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Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported Aug. 24 in the Journal of Clinical Investigation.

24 Aug 2023

Researchers find link between topography of the genome and presence of cancer mutations

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer.

24 Aug 2023

Largest genetic study of heart failure finds new risk factors

In a new study co-led by investigators at the United States Department of Veterans Affairs and Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, a global team of scientists conducted one of the largest genetic association studies on heart failure to date.

24 Aug 2023

Brain circuitry repair offers hope for new Parkinson's disease treatments

Van Andel Institute scientists have identified a series of processes that help the brain adapt to damage caused by breakdowns in circuits that govern movement, cognition and sensory perception.

24 Aug 2023

Engineered adeno-associated virus vector yields high transduction of the brain vasculature

Researchers have developed an engineered adeno-associated virus (AAV) vector that yields high transduction of brain vascular pericytes and smooth muscle cells.

24 Aug 2023

Specific alterations in brain structural connectivity may be an early diagnostic marker for ASD

ASD, a complex neurodevelopmental disorder, is known to be linked to altered brain development. However, precise markers that can accurately diagnose ASD at the individual level have been elusive.

24 Aug 2023

Bystander defibrillation improves 30-day survival even with short ambulance response times

Using a defibrillator for a cardiac arrest victim improves 30-day survival even with ambulance response times as short as two minutes, according to research presented at ESC Congress 2023.

24 Aug 2023

The role played by the gut microbiome in metabolizing selected sweeteners

The current evidence on the role of the gut microbiome in metabolizing sweeteners and their metabolites.

24 Aug 2023

Pioneering drug for rare kidney disease improves outcome for patients

A pioneering drug for a rare kidney disease prevents organ failure and significantly improves the outcome for patients, new research has confirmed.

24 Aug 2023

The role of orexin in the modulation of sleep and wakefulness

The current evidence of the intricate relationship between orexin, rapid eye movement (REM) sleep, and appetite.

24 Aug 2023

Ketogenic diets, gut microbiota, and health effects

The evidence on ketogenic diets (KDs) from the past three decades.

24 Aug 2023

Gonorrhoea surge in England following COVID-19 restrictions lift

Researchers analyzed the rise in gonorrhea diagnoses in England post-coronavirus disease 2019.

24 Aug 2023

Novel approach uses machine learning for quick and easy rheumatic disease diagnosis

Researchers evaluated fluorescence optical imaging as a method to accurately and rapidly diagnose rheumatic diseases of the hands.

24 Aug 2023

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

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24 Aug 2023

The most recent neuroimaging procedures and machine learning approaches for the prediction of Alzheimer’s progression

Researchers examined recent studies exploring neuroimaging modalities aided by advanced machine learning (ML) algorithms.

24 Aug 2023

Study finds examining retinal structure could provide markers for Parkinson disease

A new paper examined the retinal data from Parkinson disease patients in attempt to identify disease markers.

24 Aug 2023

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

23 Aug 2023

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

Brain lesions associated with MS memory dysfunction connect to a memory circuit

Between 30 to 50 percent of people living with multiple sclerosis (MS) will experience memory problems but the cause is uncertain.

23 Aug 2023

New gene variant linked to Parkinson's disease found in people of African ancestry

A gene variant found almost exclusively in the genomes of people of African ancestry increases the risk of developing Parkinson's disease, according to an international study of nearly 198,000 participants with this genetic background.

23 Aug 2023

Medical Condition News

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Researchers find link between topography of the genome and presence of cancer mutations

Largest genetic study of heart failure finds new risk factors

Brain circuitry repair offers hope for new Parkinson's disease treatments

Engineered adeno-associated virus vector yields high transduction of the brain vasculature

Specific alterations in brain structural connectivity may be an early diagnostic marker for ASD

Bystander defibrillation improves 30-day survival even with short ambulance response times

The role played by the gut microbiome in metabolizing selected sweeteners

Pioneering drug for rare kidney disease improves outcome for patients

The role of orexin in the modulation of sleep and wakefulness

Ketogenic diets, gut microbiota, and health effects

Gonorrhoea surge in England following COVID-19 restrictions lift

Novel approach uses machine learning for quick and easy rheumatic disease diagnosis

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

The most recent neuroimaging procedures and machine learning approaches for the prediction of Alzheimer’s progression

Study finds examining retinal structure could provide markers for Parkinson disease

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

Brain lesions associated with MS memory dysfunction connect to a memory circuit

New gene variant linked to Parkinson's disease found in people of African ancestry

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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