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Study reveals potential targets to improve the treatment of myeloma

A ground-breaking study by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has revealed crucial insights into the role of the histone methyltransferase NSD2 and its epigenetic target PKCα in causing t(4;14) translocated multiple myeloma (MM), a high-risk subtype of blood cancer, to be more aggressive and resistant to treatment.

12 Sep 2023

Shorter telomere length of leucocytes may signal heightened dementia risk

Shorter telomeres on the ends of white blood cell chromosomes may signal a heightened dementia risk, suggest the results of a large long term study, published online in the journal General Psychiatry.

12 Sep 2023

How COVID-19 targets the pancreas revealed

The study uncovers the role of the PLAC8 protein in making the human pancreas vulnerable to SARS-CoV-2 infection, leading to pancreatic injury and complications in severe COVID-19 cases. The findings open up new avenues for understanding how the virus affects multiple organ systems and offer a potential target for future treatments.

12 Sep 2023

Unlocking the future of dementia: Your telomere length could predict your risk

The recent study in General Psychiatry found that leukocyte telomere length (LTL) is significantly associated with the risk of developing dementia, especially Alzheimer's disease. Using data from over 430,000 individuals, the study suggests that telomere length could serve as a predictive biomarker for brain health and dementia risk.

12 Sep 2023

Many 'mild' COVID patients still battling lung damage a year later

A recent PLoS ONE study reveals that severe COVID-19 patients are at higher risk of long-term pulmonary impairments, with nearly half experiencing reduced lung function a year after disease onset. The study underscores the need for ongoing monitoring to manage 'long COVID' symptoms effectively.

12 Sep 2023

Sedentary behavior linked to increased risk of dementia in adults over 60

Adults aged 60 and older who spend more time engaging in sedentary behaviors like sitting while watching TV or driving may be at increased risk of developing dementia, according to a new study by USC and University of Arizona researchers.

12 Sep 2023

AI could improve accuracy and speed of lupus nephritis diagnosis

In the ever-perilous autoimmune disease world of systemic lupus erythematosus (SLE or lupus), up to 60% of adult patients and 80% of children will develop lupus nephritis (LN), and up to half of those will move on to end-stage renal disease.

12 Sep 2023

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

An article published in NPJ Aging, a Springer Nature journal, reveals that natural production of auto-antibodies increases with age and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19.

12 Sep 2023

Doctors must address Parkinson’s patients’ hidden burden of stigma, report says

Even the best treatment approaches for Parkinson's disease are inadequate if they do not address patients' feelings of social rejection, isolation, loneliness and other psychosocial effects of stigma, according to a report from experts specializing in Parkinson's and other movement disorders.

12 Sep 2023

Idrevadiloride in hypertonic saline improves lung function in people with primary ciliary dyskinesia, trial shows

Primary ciliary dyskenisia (PCD) is a rare genetic disease that causes the tiny hair-like filtration structures in the respiratory tract to stop working.

12 Sep 2023

University of Kentucky's cardiovascular scientist recognized for excellence in hypertension research

The University of Kentucky's Vice President for Research and leading cardiovascular scientist is being recognized for her foundational work in the field of hypertension with a prestigious award from the American Heart Association (AHA).

12 Sep 2023

Both high- and normal-protein diets are effective for weight loss in adults with Type 2 diabetes

New findings from the University of Alabama at Birmingham indicate that the type of protein in the diet is not as important as the overall amount of weight loss for those with Type 2 diabetes.

12 Sep 2023

Untangling a puzzle at the heart of multimorbidity

Multimorbidity describes the state of having more than one disease. Anthony Webster sought to untangle a puzzle at the heart of multimorbidity: does having had disease make a patient more likely to have another disease, independent of broad risk factors, such as age, smoking status, or weight?

12 Sep 2023

Unified and concentrated lung cancer advocacy program results in 25% increase in research funding

A unified and concentrated lung cancer advocacy program in the United States resulted in a 25 percent increase in funding to a U.S.-based lung cancer research program, according to a presentation given today at the International Association for the Study of Lung Cancer 2023 World Conference on Lung Cancer in Singapore.

12 Sep 2023

Loneliness, depression and social isolation linked to digestive diseases in older adults

While life expectancy rates for older Americans are rising, nearly 40% of adults report living with a digestive disease of some kind.

12 Sep 2023

Intensity-modulated radiation therapy reduces radiation exposure to heart and lungs in NSCLC patients

Intensity-modulated radiation therapy (IMRT) should be the preferred choice when treating patients with locally advanced non-small cell lung cancer (NSCLC), as it reduces radiation exposure to the heart and lungs, according to researchers at The University of Texas MD Anderson Cancer Center.

12 Sep 2023

Arf1 inhibition induces tumor regression by promoting T cell infiltration

In recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have been highly successful and have become an important basis for the future treatment of cancers.

12 Sep 2023

Single-ventricle physiology correlates with higher short-term mortality among adult congenital heart disease transplant recipients

UCLA-led research finds that among adult congenital heart disease (CHD) transplant recipients, single-ventricle physiology correlated with higher short-term mortality.

12 Sep 2023

Chemotherapy drug may promote cancer growth by injuring surrounding cells

A standard chemotherapy drug injures surrounding non-cancer cells, which can then awakens dormant cancer cells and promotes cancer growth, according to a new study publishing September 12th in the open access journal PLOS Biology by Ramya Ganesan of Emory University, US, and colleagues.

12 Sep 2023

Stem cells can be used to repair damaged lung tissue in COPD patients

For the first time, researchers have shown it is possible to repair damaged lung tissue in patients with chronic obstructive pulmonary disease (COPD) using the patients' own lung cells.

12 Sep 2023

Medical Condition News

Study reveals potential targets to improve the treatment of myeloma

Shorter telomere length of leucocytes may signal heightened dementia risk

How COVID-19 targets the pancreas revealed

Unlocking the future of dementia: Your telomere length could predict your risk

Many 'mild' COVID patients still battling lung damage a year later

Sedentary behavior linked to increased risk of dementia in adults over 60

AI could improve accuracy and speed of lupus nephritis diagnosis

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

Doctors must address Parkinson’s patients’ hidden burden of stigma, report says

Idrevadiloride in hypertonic saline improves lung function in people with primary ciliary dyskinesia, trial shows

University of Kentucky's cardiovascular scientist recognized for excellence in hypertension research

Both high- and normal-protein diets are effective for weight loss in adults with Type 2 diabetes

Untangling a puzzle at the heart of multimorbidity

Unified and concentrated lung cancer advocacy program results in 25% increase in research funding

Loneliness, depression and social isolation linked to digestive diseases in older adults

Intensity-modulated radiation therapy reduces radiation exposure to heart and lungs in NSCLC patients

Arf1 inhibition induces tumor regression by promoting T cell infiltration

Single-ventricle physiology correlates with higher short-term mortality among adult congenital heart disease transplant recipients

Chemotherapy drug may promote cancer growth by injuring surrounding cells

Stem cells can be used to repair damaged lung tissue in COPD patients

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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