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Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study demonstrates that inhibiting stromal class I histone deacetylases (HDACs) can effectively slow down pancreatic cancer progression, shedding light on a new therapeutic approach targeting the tumor microenvironment.

10 Dec 2023

Key role of ion and water influx in T cell migration uncovered

Research reveals that T cell migration relies on ion and water influx for actin polymerization and movement, with the WNK1 kinase playing a critical role in regulating these processes, offering new insights into adaptive immunity.

10 Dec 2023

Study assesses links between early negative life events, orbitofrontal cortical thickness and depression in young adults

Study found that early negative life events predict depressive symptoms in young adulthood, but not through accelerated thinning of the orbitofrontal cortex (OFC) across adolescence, challenging previous assumptions about the brain's structural changes and mental health.

10 Dec 2023

Study links air pollution to increased risks of preterm birth and low birth weight

Study highlights the importance of reducing air pollution exposure during pregnancy to prevent risks like preterm birth and low birth weight, showing a strong correlation between air quality and maternal and neonatal health outcomes.

10 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Study links organic Mediterranean diet to improved male fertility

Researchers in Italy have found that a low-carbohydrate organic Mediterranean diet significantly enhances male fertility by increasing testosterone levels and reducing sperm DNA fragmentation, offering new dietary guidelines for improving male reproductive health.

10 Dec 2023

Understanding why healthy cells help cancer cells to evade treatment

Chemotherapy becomes less effective because healthy cells push cancer cells to grow more slowly, according to two studies from researchers at UCL and Yale.

9 Dec 2023

Using near-infrared spectroscopy to study how infant brains respond to touch

Researchers from Tokyo Metropolitan University have measured how oxygenated hemoglobin levels in the blood change in infants' brains in response to touch.

9 Dec 2023

Women over 50 can safely reduce mammogram frequency after breast cancer surgery

Women 50 or older who de-escalated to less-frequent mammography three years after curative surgery for early-stage breast cancer had similar outcomes to women who received annual mammography, according to results from the Mammo-50 trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

Patients with low-risk ductal carcinoma in situ (DCIS) who skipped adjuvant radiotherapy after breast-conserving surgery had comparable five-year outcomes to those with high-risk DCIS who received adjuvant radiotherapy, according to results from the E4112 clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

New insights into how anti-obesity drugs could help prevent kidney disease

Data from Australian researchers could partly explain why a trial of a new drug for diabetes, was recently halted because it was found to be so effective.

8 Dec 2023

Study identifies targetable fusion RNAs in breast cancer

Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Viruses have limited genetic material - and few proteins - so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins.

8 Dec 2023

Women undergoing chemotherapy may not benefit from common fertility protection drug

A new study from Karolinska Institutet in Sweden has found no evidence that a common drug used to protect the ovaries of women undergoing chemotherapy increases their chances of having children after cancer treatment.

8 Dec 2023

Neuroscientists decipher secrets of the brain’s language hub and its replacement strategy

A University of Iowa-led team of international neuroscientists have obtained the first direct recordings of the human brain in the minutes before and after a brain hub crucial for language meaning was surgically disconnected.

8 Dec 2023

Genome-wide study shows strong negative correlation between reproduction and lifespan

A University of Michigan-led study based on a review of genetic and health information from more than 276,000 people finds strong support for a decades-old evolutionary theory that sought to explain aging and senescence.

8 Dec 2023

Small molecule drug shows promise as potential new treatment for multiple sclerosis

CAMH-led pre-clinical studies using a small molecule drug have shown promise as a potential new treatment for multiple sclerosis (MS). The results have been published today in the journal Science Advances.

8 Dec 2023

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

It only takes holding your breath for slightly too long to understand that too little oxygen is bad for you. But can you also have too much? Indeed, breathing air with a higher oxygen level than your body needs can cause health problems or even death.

8 Dec 2023

Unmasking system hesitancies that aggravated the COVID-19 tragedy

More than 1.2 million people have died in the United States during the COVID-19 pandemic to date, more documented deaths than any other nation on Earth.

8 Dec 2023

New discovery could provide a potential target to treat diabetes

Researchers at Case Western Reserve University and University Hospitals have identified an enzyme that blocks insulin produced in the body - a discovery that could provide a new target to treat diabetes.

8 Dec 2023

Medical Research News

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Key role of ion and water influx in T cell migration uncovered

Study assesses links between early negative life events, orbitofrontal cortical thickness and depression in young adults

Study links air pollution to increased risks of preterm birth and low birth weight

Study explores the intricate gut-brain-liver connection and its impact on health

Study links organic Mediterranean diet to improved male fertility

Understanding why healthy cells help cancer cells to evade treatment

Using near-infrared spectroscopy to study how infant brains respond to touch

Women over 50 can safely reduce mammogram frequency after breast cancer surgery

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

New insights into how anti-obesity drugs could help prevent kidney disease

Study identifies targetable fusion RNAs in breast cancer

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Women undergoing chemotherapy may not benefit from common fertility protection drug

Neuroscientists decipher secrets of the brain’s language hub and its replacement strategy

Genome-wide study shows strong negative correlation between reproduction and lifespan

Small molecule drug shows promise as potential new treatment for multiple sclerosis

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

Unmasking system hesitancies that aggravated the COVID-19 tragedy

New discovery could provide a potential target to treat diabetes

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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