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Infants with cystic fibrosis show stunted gut microbiome development

Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut microbiome (communities of bacteria) of infants with cystic fibrosis (CF) compared to that of healthy infants, and how these alterations may adversely affect their health.

14 Feb 2025

Risk of bleeding with blood thinners reduces over time

Blood thinners prescribed after blood clots in leg or lung initially increase the risk of bleeding, especially in women and elderly.

14 Feb 2025

Evidence increasingly links ultra-processed food consumption to weight gain

Research shows that promoting fruits and vegetables isn't enough to combat weight gain, highlighting the significant role of ultra-processed foods in obesity.

14 Feb 2025

Study highlights the need for more diversity in vaginal microbiome research

This study emphasizes the need for global equity in vaginal microbiome research, addressing health disparities and improving female health strategies worldwide.

14 Feb 2025

Leveling up NGS workflows with INTEGRA Biosciences’ solutions

INTEGRA Biosciences offers liquid handling solutions and magnetic modules to streamline every stage of NGS sample preparation. These innovative tools help to reduce errors, improve the precision and reliability of sequencing data, and provide more efficient processes.

From INTEGRA Biosciences 14 Feb 2025

Interferon pathway activation identified as key driver in OPLL pathogenesis

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal cord compression. This condition is more prevalent in Asian countries and has been associated with various genetic and hormonal factors.

14 Feb 2025

Engineering safe and effective vaccinia virus vectors for next-generation vaccines

Announcing a new article publication for Zoonoses journal. Vaccinia virus (VACV) confers cross-protective immunity against the variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine. Despite the global eradication of smallpox in the 1980s, research efforts involving VACV have continued due to the potential threat of the variola virus being used as a bioweapon, which poses grave risks to human health.

14 Feb 2025

Self-sampling: New option for HPV screening

Genital human papillomavirus is the most common sexually transmitted infection in the United States and is thought to be responsible for more than 99% of cervical cancers.

14 Feb 2025

Researchers uncover cause of persistent blood clots despite treatment

A team of researchers have made a new discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

14 Feb 2025

Harvard researchers map 70,000 synaptic connections in rat brain

Harvard researchers have mapped and catalogued more than 70,000 synaptic connections from about 2,000 rat neurons, using a silicon chip capable of recording small yet telltale synaptic signals from a large number of neurons.

14 Feb 2025

Researchers identify genetic cause of Lennox-Gastaut syndrome

Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, Baylor Genetics and collaborating institutions provided a long-awaited and rare genetic diagnosis in a child with Lennox-Gastaut syndrome, a type of developmental epileptic encephalopathy (DEE), associated with a severe, complex form of epilepsy and developmental delay.

14 Feb 2025

Addressing the global challenge of bacterial STIs

According to the World Health Organization (WHO), hundreds of millions of new cases of bacterial sexually transmitted infections (STIs) are reported worldwide each year. Many infections go undiagnosed due to their often silent symptoms, contributing to transmission, disease and complications such as infertility and miscarriage.

14 Feb 2025

IgG-guided diet outperforms sham diet in clinical trial

Michigan Medicine and Cleveland Clinic researchers have found that patients with irritable bowel syndrome were more likely to experience less abdominal pain if they followed a diet guided by the results of a blood test, compared to those who followed a sham elimination diet.

13 Feb 2025

New insight into gut stem cell aging

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signaling is essential for preserving the intestinal stem cell population during aging.

13 Feb 2025

Pollution shift: How truck electrification moves the burden to power plants

Electrifying heavy-duty trucks reduces on-road emissions but shifts pollution burdens to power plants, with disadvantaged communities still facing higher exposure despite overall air quality improvements.

13 Feb 2025

New biomarker can accurately predict outcomes in meningiomas and breast cancers

Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD Anderson Cancer Center have uncovered a biomarker capable of accurately predicting outcomes in meningioma brain tumors and breast cancers.

13 Feb 2025

People with depression at higher risk for long-term physical health conditions

Adults with a history of depression gain long-term physical conditions around 30% faster than those without, according to research publishing February 13th in the open-access journal PLOS Medicine.

13 Feb 2025

Discovery of gene silencer offers hope for autosomal dominant leukodystrophy

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene "silencer" that resides in junk DNA is directly sparing people from a devastating and fatal progressive neurological disease.

13 Feb 2025

Menthol cigarettes contribute to higher death rates in smokers

In a large, nationwide study led by the American Cancer Society (ACS), researchers found mortality risks for smoking menthol cigarettes were higher than non-menthol cigarettes for death from any cause and cardiovascular diseases, especially heart diseases.

13 Feb 2025

Study reveals brain circuit linked to human creativity

A new study led by researchers at Mass General Brigham suggests that different brain regions activated by creative tasks are part of one common brain circuit.

13 Feb 2025