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A scaffolded vaccine approach for broader influenza protection

Most people who get the seasonal influenza vaccine – which contains strains of viruses from distinct virus subtypes – mount a strong immune response to one strain, leaving them vulnerable to infection by the others, and researchers have long wondered what impacts such variable responses more – host genetics or prior exposure to virus strains.

19 Dec 2024

Pregnant women must be prioritized in pandemic vaccination programs

The vast majority of women who contract bird flu during pregnancy and their unborn baby will die from the virus, according to a new study. And the findings stress the importance of early inclusion of pregnant women in public health vaccination programs during pandemics.

19 Dec 2024

Nogo-A inhibition demonstrates potential for spinal cord injury recovery

The latest study results have been published online in the renowned "The Lancet Neurology" journal. A multi-centre clinical trial (NISCI trial: Nogo-A Inhibition in acute Spinal Cord Injury Study) investigated the antibody NG 101 (anti-Nogo-A), which blocks and thus neutralizes the body's own Nogo-A protein.

19 Dec 2024

A new link between brain health and mitochondrial function

New findings in mice have uncovered a crucial mechanism linking neuronal activity to mitochondrial function, researchers report, revealing a potential pathway to combat age-related cognitive decline. Mitochondria play a pivotal role in meeting the dynamic energy demands of neuronal activity, producing adenosine triphosphate (ATP) primarily via oxidative phosphorylation (OXPHOS).

19 Dec 2024

New insights into glioblastoma resistance to temozolomide

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used as the front-line medicine in its treatment.

19 Dec 2024

Unleashing the potential of biological timekeeping

Living organisms monitor time – and react to it – in many different ways, from detecting light and sound in microseconds to responding physiologically in pre-programmed ways, via their daily sleep cycle, monthly menstrual cycle, or to changes in the seasons.

19 Dec 2024

Using impulse oscillometry for lung function testing in preterm children

Infants born preterm remain vulnerable to numerous health complications, such as respiratory distress syndrome, chronic lung disease, and pulmonary dysfunction.

19 Dec 2024

Research sheds light on the ethical complexities in conducting Industry-funded cannabis studies

In the first study of its kind, research led by the Centre for Addiction and Mental Health (CAMH) sheds light on the ethical complexities and systemic barriers facing scientists conducting cannabis research funded by the for-profit cannabis industry.

19 Dec 2024

Early physical therapy can help prevent lingering symptoms after concussion

People who suffer from continued symptoms of concussion should seek a referral to physical therapy as soon as possible, new research from Oregon Health & Science University suggests.

19 Dec 2024

Sulfide-producing bacteria may explain lingering symptoms in Crohn's disease

A study from University of Michigan researchers may provide an explanation for why some patients with Crohn's disease continue to experience symptoms, even in the absence of inflammation.

19 Dec 2024

Study finds facial shape differences linked to schizophrenia and bipolar disorder

A study published in Psychiatry Research identifies subtle differences in facial shapes that may be linked to the diagnosis of schizophrenia and bipolar disorder.

19 Dec 2024

Study uncovers a previously unknown genetic link to autism spectrum disorder

New research published in The American Journal of Human Genetics has identified a previously unknown genetic link to autism spectrum disorder (ASD). The study found that variants in the DDX53 gene contribute to ASD, providing new insights into the genetic underpinnings of the condition.

19 Dec 2024

Innovative method to study ALS could lead to personalized treatments

Amyotrophic lateral sclerosis (ALS) is a fast-progressing neurodegenerative disease with an average survival time of three years.

19 Dec 2024

Drinking more coffee linked to reduced cognitive decline in people with atrial fibrillation

Drinking multiple cups of coffee a day may help prevent cognitive decline in people with atrial fibrillation (AFib or AF), according to new research published on Dec. 14, 2024 in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

19 Dec 2024