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Targeted microglia replacement shows promise against fatal neurodegenerative conditions

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

6 Aug 2025

Heart cells adapt and stretch to shape a healthy beating heart

Researchers at the Francis Crick Institute have discovered that the heart's own contractions trigger biological signals that guide the formation of a functional beating heart.

6 Aug 2025

Many patients with high-risk myelodysplastic syndromes do not receive guideline-recommended treatment

Most patients with high-risk myelodysplastic syndromes (MDS) do not receive guideline-recommended treatment with hypomethylating agents (HMAs), according to results published in Blood Neoplasia.

6 Aug 2025

Air purifiers can lower blood pressure in at-risk adults

Using portable high-efficiency particulate air (HEPA) purifiers at home can significantly lower systolic blood pressure (SBP) in adults with elevated baseline readings — even in areas with relatively low overall air pollution levels, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

6 Aug 2025

Immune aging drives the progression of type 2 diabetes

Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell failure.

6 Aug 2025

TEER shows promising outcomes in elderly patients with atrial functional mitral regurgitation

The mitral valve controls blood flow between the heart's left atrium and ventricle. When structural changes affect the atrium or valve, it may not close fully-causing blood to leak backwards, a condition known as atrial functional mitral regurgitation (AFMR).

6 Aug 2025

Gut microbiota and short chain fatty acids influence bone health in postmenopausal osteoporosis

Postmenopausal osteoporosis (PMOP) is framed as a systemic bone disease driven by estrogen withdrawal, but emerging evidence positions gut dysbiosis and its fermentation products—short-chain fatty acids (SCFAs)—as equally influential regulators of skeletal fate.

6 Aug 2025

Prime editing reverses symptoms of severe childhood neurological disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

From The Jackson Labs 6 Aug 2025

Study finds link between past life memories and mental health challenges

Researchers analyzed the profile of adults who claim to have past-life memories, the features of these memories, and their associations with mental health, happiness, and religiosity/spirituality.

6 Aug 2025

Staying in hurricane affected zones linked to increased mortality in the elderly

Hurricanes and related natural catastrophes like flooding are becoming more severe and more frequent around the world. Older people are especially at risk, but relatively little is known about long-term health effects.

6 Aug 2025

Diabetes drug linked to lower risks of dementia and early death

New research in Diabetes, Obesity and Metabolism reveals that metformin, a medication traditionally prescribed to treat diabetes, is linked to lower risks of dementia and early death.

6 Aug 2025

Low oxygen environment protects brain and restores movement in mice with Parkinson's

Researchers from the Broad Institute and Mass General Brigham have shown that a low-oxygen environment - similar to the thin air found at Mount Everest base camp - can protect the brain and restore movement in mice with Parkinson's-like disease.

6 Aug 2025

Apple snail eye regeneration offers new insights into human sight restoration

The eye of the apple snail is unusually similar to a human eye-but, unlike human eyes, it can regrow itself if injured or even amputated.

6 Aug 2025

Excessive screen time linked to higher cardiometabolic risk in youth

Children and young adults who spend excessive hours glued to screens and electronic devices may have higher risks for cardiometabolic diseases, such as high blood pressure, high cholesterol and insulin resistance, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

6 Aug 2025

HOXB13 emerges as a context-dependent regulator in cancer biology

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer.

5 Aug 2025

Targeting lactate metabolism offers new avenues for cancer treatment

Lactic acid (LA) has transitioned from being perceived as a mere glycolytic waste product to a pivotal regulator of tumor-immune crosstalk.

5 Aug 2025

Researchers question the historical basis of ancient psychedelic rituals

A new article in the peer-reviewed journal Psychedelic Medicine takes aim at one of the most influential, and controversial, narratives in comparative psychedelic culture: the idea that ancient Greek mystery rites at Eleusis were fueled by psychedelic drugs.

5 Aug 2025

Medical Research News

Targeted microglia replacement shows promise against fatal neurodegenerative conditions

Heart cells adapt and stretch to shape a healthy beating heart

Many patients with high-risk myelodysplastic syndromes do not receive guideline-recommended treatment

Air purifiers can lower blood pressure in at-risk adults

Immune aging drives the progression of type 2 diabetes

TEER shows promising outcomes in elderly patients with atrial functional mitral regurgitation

Gut microbiota and short chain fatty acids influence bone health in postmenopausal osteoporosis

Prime editing reverses symptoms of severe childhood neurological disease

Study finds link between past life memories and mental health challenges

Staying in hurricane affected zones linked to increased mortality in the elderly

Diabetes drug linked to lower risks of dementia and early death

Low oxygen environment protects brain and restores movement in mice with Parkinson's

Apple snail eye regeneration offers new insights into human sight restoration

Excessive screen time linked to higher cardiometabolic risk in youth

HOXB13 emerges as a context-dependent regulator in cancer biology

Targeting lactate metabolism offers new avenues for cancer treatment

Researchers question the historical basis of ancient psychedelic rituals

Solastalgia identified as key concept linking climate change to mental health

Australian study finds lasting relief for back pain through cognitive functional therapy

Mother’s genetics may play an important role in influencing her child's weight

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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