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Genetic analysis reveals novel traits associated with COVID-19 severity

Researchers in the United States have conducted genetic correlation studies revealing novel traits associated with the development of severe coronavirus disease 2019 (COVID-19).

23 Dec 2020

E-cigarettes, as consumer products, are not associated with smoking cessation

E-cigarette use has risen steeply and mostly without regulation over the past decade. The devices have diversified into a dizzying array of vape pens, tank systems, "mods," and more, mass-marketed and sold to the public.

23 Dec 2020

First UK lockdown during COVID-19 pandemic negatively impacted dementia care

Researchers in the United Kingdom have conducted an extensive survey exploring the impact that lockdown had on people living with low prevalence and young-onset dementias during the first wave of the coronavirus disease 2019 (COVID-19) pandemic.

23 Dec 2020

Giving antimalarial medicines to children during the rainy season reduces malaria deaths

Giving antimalarial medicines to children monthly during the rainy season cut malaria deaths in children by 42 per cent, making a case for wide implementation in malaria-endemic African regions, a study found.

23 Dec 2020

Modeling the phases of quarantine reveals two-phase route is always better than one

New research into this question shows that the second wave of an epidemic is very different if a population has a homogenous distribution of contacts, compared to the scenario of subpopulations with diverse number of contacts.

23 Dec 2020

SARS-CoV-2 mutations may evade T cell immunity

A potentially disturbing new study suggests that SARS-CoV-2 may be undergoing strategic mutations that affect the host immune capacity to recognize and combat the pathogen via T effector cells.

23 Dec 2020

COVID-19 severity could be linked to genetic variance

A new study describes some potentially important genetic factors in the host that may shape the clinical symptoms and signs of the disease.

23 Dec 2020

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

A new study sheds light on some important differences between asymptomatic and symptomatic patients with coronavirus disease 2019 (COVID-19).

23 Dec 2020

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers claim to have reproduced disease mechanisms due to coronavirus disease 2019 (COVID-19) in the fruit fly, Drosophila, while also providing proof of the efficacy of one drug against these disease processes. If validated, these findings represent a new understanding of how the virus causes neurological symptoms that could help develop more effective therapies.

23 Dec 2020

Study assesses link between secondary bloodstream infection and severe COVID-19

People with severe COVID-19 and a secondary blood infection were significantly sicker upon hospital admission, had longer hospital stays and poorer outcomes, according to a Rutgers study.

23 Dec 2020

Novel computational tool can systematically analyze cell images in C. elegans

A joint research team co-led by City University of Hong Kong (CityU) has developed a novel computational tool that can reconstruct and visualise three-dimensional (3D) shapes and temporal changes of cells, speeding up the analysing process from hundreds of hours by hand to a few hours by the computer.

23 Dec 2020

Changes in consciousness linked to the same brain network for sleep and anesthesia

The loss and return of consciousness is linked to the same network of brain regions for both sleep and anesthesia, according to new research published in JNeurosci.

23 Dec 2020

Common ophthalmic devices measure corneal parameters using different technologies

As the recently published article in the journal Open Ophthalmology Journal shows, there are significant differences among the measures of corneal parameters obtained by the three most commonly used ophthalmic devices, called topographers.

23 Dec 2020

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Researchers at the Kobe University Graduate School of Medicine have revealed that alterations in fetal microglia resulting from maternal inflammation could contribute towards the onset of developmental and psychiatric disorders.

23 Dec 2020

Modulating BST2 expression on blood stem cells may help regulate cell activation during chronic infections

When a person has an infection, the body activates immune responses to fight it. IFNγ is an inflammatory molecule produced by the immune system that helps fight infections.

23 Dec 2020

Long-term opioid use cannot treat chronic pain, has serious health consequences

A broken heart is often harder to heal than a broken leg. Now researchers say that a broken heart can contribute to lasting chronic pain.

22 Dec 2020

Researchers uncover key regulation step that inhibits tumor growth

Most living things need oxygen to grow and thrive. Even cancerous tumors. That's why tumors will readily sprout new blood vessels if their oxygen is starved, creating new lifelines for survival.

22 Dec 2020

Research shows how colanic acid extends lifespan in C. elegans

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.

22 Dec 2020

Study finds sex and age-based differences among youth who experience nonfatal opioid overdose

Results of a national study show significant sex and age-based differences among youth and young adults who experience a nonfatal opioid overdose.

22 Dec 2020

First human clinical trial validates the practicality, accuracy of oxygen-sensing liquid bandage

In the first human clinical trial, researchers at Massachusetts General Hospital and surgeons at Beth Israel Deaconess Medical Center have validated the practicality and accuracy of an oxygen-sensing liquid bandage that measures the concentration of oxygen in transplanted tissue

22 Dec 2020

Medical Research News

Genetic analysis reveals novel traits associated with COVID-19 severity

E-cigarettes, as consumer products, are not associated with smoking cessation

First UK lockdown during COVID-19 pandemic negatively impacted dementia care

Giving antimalarial medicines to children during the rainy season reduces malaria deaths

Modeling the phases of quarantine reveals two-phase route is always better than one

SARS-CoV-2 mutations may evade T cell immunity

COVID-19 severity could be linked to genetic variance

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

Researchers use fruit fly model to understand COVID-19-related neurological complications

Study assesses link between secondary bloodstream infection and severe COVID-19

Novel computational tool can systematically analyze cell images in C. elegans

Changes in consciousness linked to the same brain network for sleep and anesthesia

Common ophthalmic devices measure corneal parameters using different technologies

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Modulating BST2 expression on blood stem cells may help regulate cell activation during chronic infections

Long-term opioid use cannot treat chronic pain, has serious health consequences

Researchers uncover key regulation step that inhibits tumor growth

Research shows how colanic acid extends lifespan in C. elegans

Study finds sex and age-based differences among youth who experience nonfatal opioid overdose

First human clinical trial validates the practicality, accuracy of oxygen-sensing liquid bandage

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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