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U-M and Karmanos receive NCI grant to find new solutions for prostate cancer

Michigan's two elite cancer programs are joining forces to find new solutions for prostate cancer. The University of Michigan Rogel Cancer and the Barbara Ann Karmanos Cancer Institute have received a prestigious $9.2 million grant from the National Cancer Institute.

23 Sep 2019

Discrete choice experiments can predict real-world healthcare choices, research shows

Value in Health, the official journal of ISPOR- the professional society for health economics and outcomes research, announced today the publication of research demonstrating that discrete choice experiments are able to predict real-world healthcare choices.

23 Sep 2019

Researchers use high-throughput mutagenesis approach to study ALS

Amyotrophic lateral sclerosis is a devastating and incurable nervous system disease that affects nerve cells in the brain and spinal cord, causing loss of muscle control and normally death within a few years of diagnosis.

23 Sep 2019

Fat mass index, not BMI, linked to higher risk of cardiovascular events in diabetic patients

In people with diabetes, fat mass index, not body mass index, is associated with a higher risk of cardiovascular events, according to new research in CMAJ.

23 Sep 2019

How one family counters epilepsy and caregiver stress by giving back

For people with epilepsy, seizures affect almost every aspect of their lives. The seizures also affect their caregivers' lives, with impacts on physical health, emotional functioning, social relationships, employment and finances.

23 Sep 2019

Conference reviews effects of tobacco products, underscores the importance of oral health

On September 14, 2018 AADR held the "Oral Health Effects of Tobacco Products: Science and Regulatory Policy" meeting in Bethesda, Maryland, USA.

23 Sep 2019

African bacterium resists almost all drugs

It looks like it’s time to pay the piper. The first extensively drug-resistant (XDR) strain of Salmonella typhimurium, called ST313 sublineage II.1, has cropped up in the Democratic Republic of Congo (DRC). This fails to respond to any of the antibiotics that are commonly used in the DRC, except for ciprofloxacin. And to make things worse, one sample has been isolated that shows incomplete response even to this last drug.

22 Sep 2019

Faster, cheaper, better: improved gene therapy tool production

The heart of modern therapy is increasingly personalized and targeted at specific cellular or genetic deficits. This requires gene therapy, in many cases. A new study, published on 19 September 2019 in the journal Nature, describes an improved way to produce purified gene carrier viruses called AAVs cheaply and quickly, from the culture medium.

22 Sep 2019

New study identifies potential enzyme target for diabetic retinopathy

A new study shows that diabetic retinopathy (DR), or retinal disease caused by the high blood glucose levels in diabetes mellitus, is due to the death of retinal cells because of the high levels of a pro-enzyme called lysyl oxidase propeptide (LOX-PP). This could help researchers develop specific treatments by targeting this molecule.

22 Sep 2019

RNA hitches lysosome rides to make proteins far away from the nucleus

Proteins inside a cell are often made at the site where they are used, rather than being shipped long distances. This is so with nerve cells which have long cell extensions in the form of axons and dendrites, up to four feet long in some case

22 Sep 2019

UTHealth's innovative cancer-fighting projects receive $11 million CPRIT funding

Five innovative cancer-fighting projects at The University of Texas Health Science Center at Houston received just over $11 million during the latest round of grants awarded by the Cancer Prevention and Research Institute of Texas

21 Sep 2019

Leukemia drug appears to be effective in treating deadly pediatric brain tumor

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional team led by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego.

21 Sep 2019

Researchers aim to explore effects of age, gender on brain injury mechanics

Traumatic brain injury and chronic traumatic encephalopathy have become common in athletes who suffer repeated blows to the head. Most recently, former New England Patriots tight end Rob Gronkowski revealed that he had sustained about 20 concussions during his nine-year career in the National Football League.

21 Sep 2019

Open Medicare data provides critical insights on hidden costs of health care

An interdisciplinary team of Indiana University scientists studying Medicare data have found an association between health care industry payments to medical providers for non-research expenses and what these providers charge for medical services -- shedding new light on potential hidden costs to the public.

20 Sep 2019

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

Dengue virus infects about 400 million people annually around the world, with a high prevalence in tropical and sub-tropical regions.

20 Sep 2019

Study confirms lasting impact of neonatal CPAP technology in Malawi

Malawi's national adoption of affordable, rugged, neonatal CPAP technology as a part of routine hospital care resulted in sustained improvements in the survival of babies with respiratory illness, according to a new study in the journal Pediatrics.

20 Sep 2019

Undocumented immigrants have comparable transplant survival rates to U.S. citizens

Unauthorized immigrants who receive liver transplants in the United States have comparable three-year survival rates to U.S. citizens, according to a study by researchers at UC San Francisco.

20 Sep 2019

Penn researchers develop novel vaccine to protect against genital herpes

Researchers from the Perelman School of Medicine at the University of Pennsylvania have developed a vaccine to protect against genital herpes.

20 Sep 2019

Study shows a promising alternative for HIV prevention and treatment

A new study published today in Nature Communications shows a promising alternative for those who have to take a daily pill regimen.

20 Sep 2019

UMSOM receives landmark contract from NIAID for influenza research

Kathleen Neuzil, MD, MPH, Professor of Medicine and Pediatrics and Director of the Center for Vaccine Development and Global Health at the University of Maryland School of Medicine and Dean E. Albert Reece, MD, PhD, MBA, announced that CVD has been awarded a contract from the National Institute of Allergy and Infectious Diseases, with total funding up to more than $200 million over seven years if all contract options are exercised.

20 Sep 2019