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Optimizing naloxone kit distribution to prevent opioid deaths

A new study from University of Toronto Engineering researchers points to practical strategies to prevent deaths from opioid poisoning by optimizing the distribution of naloxone kits.

24 Mar 2025

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Study shows decline in ambulatory antibiotic use in France following COVID-19 lockdown

The COVID-19 pandemic and lockdown measures in France affected health care access and prescribing patterns, leading to significant changes in outpatient (ambulatory) antibiotic use.

24 Mar 2025

High-performing clinics share effective strategies for chronic care follow-up

Regular follow-up visits are critical for managing chronic conditions, yet some primary care clinics achieve higher visit regularity than others.

24 Mar 2025

Disparities identified in treatment of chlamydia and gonorrhea in primary care

Prompt treatment of chlamydia and gonorrhea following a confirmed diagnosis is essential to prevent complications and reduce transmission. Adherence to the Centers for Disease Control (CDC) treatment guidelines in primary care settings remains a concern.

24 Mar 2025

More chest X-rays in GP practices lead to better lung cancer survival rates

A groundbreaking study has revealed a significant link between the frequency of chest x-ray referrals from GPs and earlier diagnosis and improved survival rates for lung cancer patients.

24 Mar 2025

Patients value trust and continuity over quick access to primary care

This study focuses on how primary care patients balance the trade-off between continuity of care and access to timely appointments.

24 Mar 2025

New hepatitis B vaccine outperforms standard boosters in health care workers

Health care workers are at higher risk of hepatitis B infection due to occupational exposure to blood and body fluids.

24 Mar 2025

Expectant and new fathers express the need for more support during pregnancy and childbirth

A new Penn Nursing study reveals that expectant and new fathers, particularly Black American fathers, express a significant need for more resources and support to better assist mothers during pregnancy and childbirth.

24 Mar 2025

New brain circuit involved in motion sickness could help improve metabolic health

Motion sickness is a very common condition that affects about 1 in 3 people, but the brain circuits involved are largely unknown. In the current study published in Nature Metabolism, researchers at Baylor College of Medicine, the University of Texas Health Science Center at Houston and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital describe a new brain circuit involved in motion sickness that also contributes to regulating body temperature and metabolic balance.

24 Mar 2025

Study links type 2 diabetes to weakened reward signals in the brain

The high comorbidity of type 2 diabetes (T2D) with psychiatric or neurodegenerative disorders points to a need for understanding what links these diseases.

24 Mar 2025

Family-based approach to lifestyle interventions can reduce weight and cardiovascular risks

The PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC) Study, conducted in India, aimed to assess whether a family-based approach to lifestyle interventions could improve weight management and obesity-related health outcomes among individuals with a family history of premature coronary heart disease.

24 Mar 2025

Long-term inhaled corticosteroids linked to increased health risks in COPD patients

Inhaled corticosteroids (ICS) are commonly prescribed for chronic obstructive pulmonary disease (COPD), but not recommended as first-line treatment unless patients have asthma/COPD overlap or frequent exacerbations.

24 Mar 2025

Scientists uncover role of m6A in prostate cancer progression

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the progression of prostate cancer, including driving some of its most dangerous forms of the disease.

24 Mar 2025

Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors

B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it can affect people of any age.

24 Mar 2025

New insights into how sleep reorganizes neuronal activity for better memory

Why is sleep so important for learning and memory? Neuroscientists from the Csicsvari group at the Institute of Science and Technology Austria (ISTA) provided new insight into this essential function by monitoring neuronal activity in rat brains for up to 20 hours of sleep following spatial learning.

24 Mar 2025