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SORLA protein makes fat cells oversensitive to insulin

SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA was previously known for its protective role in Alzheimer's disease.

22 Jun 2016

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

Researchers from the University of Chicago have shown that microbiota—the bacteria, viruses and other microbes living on the skin and in the digestive system—play an important role in the body's ability to accept transplanted skin and other organs.

22 Jun 2016

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society.

22 Jun 2016

Early childhood behavioral problems have larger impact on educational achievement for boys than girls

A new study finds that behavioral problems in early childhood have a larger negative effect on high school and college completion rates for boys than girls, which partially explains the substantial gender gap in educational attainment that currently exists in the United States.

22 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

Researchers play crucial role in crafting diagnostic criteria for functional GI disorders

With no laboratory test available to diagnose functional gastrointestinal disorders, proper diagnostic criteria are critical for clinicians to make an accurate determination of what ails their patients.

22 Jun 2016

Inflammatory response to mosquito bites can help spread viral infections

Mosquito bite sites are not just itchy, irritating nuisances - they also make viral infections spread by the insects far worse, new research has found.

22 Jun 2016

New study reveals conversion of oral cannabidiol to THC by acidic fluids in the stomach

A new study demonstrating the conversion of oral cannabidiol (CBD) to the psychoactive component tetrahydrocannabinol (THC) in the presence of gastric fluids could explain why children given CBD to treat epilepsy had an unexpectedly high rate of adverse effects such as sleepiness and fatigue.

22 Jun 2016

VUMC researchers aim to decode genetic underpinnings of human immune system

Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human "immunome," the genetic underpinnings of the immune system.

22 Jun 2016

Study shows how age-related inhibitory deficits can affect visual perception

Grandparents may be some of the best storytellers around, in the sense that they usually have plenty of stories to tell. What they're not always as good at, however, is staying on topic when they regale others with their tales.

22 Jun 2016

High fibre diet can help reduce food allergies

Eating a diet rich in fibre can actually shape the immune system to reduce allergies to substances such as peanuts, new research shows.

21 Jun 2016

Plant-based therapies may show modest reductions in menopausal symptoms

An analysis of more than 60 studies suggests that some plant-based therapies are associated with modest reductions in the frequency of hot flashes and vaginal dryness but no significant reduction in night sweats, according to a study appearing in the June 21 issue of JAMA.

21 Jun 2016

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Mapping the molecular structure where medicine goes to work is a crucial step toward drug discovery against deadly diseases.

21 Jun 2016

Food allergies linked to diet and gut microbiome

The development of food allergies in mice can be linked to what their gut bacteria are being fed, reports a study published June 21 in Cell Reports. Rodents that received a diet with average calories, sugar, and fiber content from birth were shown to have more severe peanut allergies than those that received a high-fiber diet.

21 Jun 2016

Study shows Alzheimer's disease can lead to diabetes

Drugs used to treat diabetes could also be used to treat Alzheimer's disease, and vice versa, according to new research from the University of Aberdeen.

21 Jun 2016

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

A new meta-analysis published in Clinical Nutrition found that cardiac surgery patients who received omega-3 polyunsaturated fatty acids (compared to placebo) in advance of surgery experienced reduced postoperative cardiac arrhythmias and significantly reduced the length of hospital stay by up to 2.4 days. The results are based on 11 RCT's with 1038 patients.

21 Jun 2016

Experts use next-generation genetic sequencing to diagnose suspected brain infections

In a proof-of-principle study, a team of physicians and bioinformatics experts at Johns Hopkins reports they were able to diagnose or rule out suspected brain infections using so called next-generation genetic sequencing of brain tissue samples.

21 Jun 2016

New protein risk score may help predict cardiovascular risk in patients with CHD

In a study appearing in the June 21 issue of JAMA, Peter Ganz, M.D., of the University of California-San Francisco, and colleagues conducted a study to develop and validate a score to predict risk of cardiovascular outcomes among patients with coronary heart disease using analysis of circulating proteins.

21 Jun 2016

Experts develop set of resolutions, conclusions to provide clarity on testosterone therapy

In an effort to address widespread concerns related to testosterone deficiency (TD) and its treatment with testosterone therapy, a group of international experts has developed a set of resolutions and conclusions to provide clarity for physicians and patients.

21 Jun 2016

Unmanned drones could be economical to deliver vaccines quickly in developing countries

Using unmanned drones to deliver vaccines in low- and middle-income countries may save money and improve vaccination rates, new research led by the Johns Hopkins Bloomberg School of Public Health and the Pittsburgh Supercomputing Center suggests.

21 Jun 2016

Medical Research News

SORLA protein makes fat cells oversensitive to insulin

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Early childhood behavioral problems have larger impact on educational achievement for boys than girls

New CAR-based therapy using combined cancer target could be effective for solid tumors

Researchers play crucial role in crafting diagnostic criteria for functional GI disorders

Inflammatory response to mosquito bites can help spread viral infections

New study reveals conversion of oral cannabidiol to THC by acidic fluids in the stomach

VUMC researchers aim to decode genetic underpinnings of human immune system

Study shows how age-related inhibitory deficits can affect visual perception

High fibre diet can help reduce food allergies

Plant-based therapies may show modest reductions in menopausal symptoms

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Food allergies linked to diet and gut microbiome

Study shows Alzheimer's disease can lead to diabetes

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

Experts use next-generation genetic sequencing to diagnose suspected brain infections

New protein risk score may help predict cardiovascular risk in patients with CHD

Experts develop set of resolutions, conclusions to provide clarity on testosterone therapy

Unmanned drones could be economical to deliver vaccines quickly in developing countries

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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