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St. Jude scientists develop insights to guide development of powerful novel anti-influenza drugs

By analyzing the molecular details of how artificially created drug-resistant flu strains manage to survive treatment, St. Jude Children's Research Hospital scientists have developed insights to guide development of powerful new anti-influenza drugs. These compounds will target a viral enzyme critical to the virus' proliferation in the body.

15 Mar 2016

UCSF study marks important step toward finding cure for Ebola

In experiments carried out partly at the Department of Energy's SLAC National Accelerator Laboratory, scientists have determined in atomic detail how a potential drug molecule fits into and blocks a channel in cell membranes that Ebola and related "filoviruses" need to infect victims' cells.

15 Mar 2016

Prognostic test could help lower cancer recurrence for colorectal patients

Colorectal cancer, one of the most commonly diagnosed cancers in the United States, is not a commonly discussed disease. Often symptomless in early stages, the cancer is more difficult to treat as it progresses, requiring chemotherapy in later stages. Researchers at the University of Notre Dame are working on a way to identify patients who would benefit from chemotherapy before the cancer progresses.

15 Mar 2016

New blood test may potentially facilitate detection of Alzheimer's disease at early stage

Today, Alzheimer's disease is diagnosed too late. In collaboration with a research team at the university and German Center for Neurogenerative Diseases in Göttingen, Researchers at Ruhr-Universität Bochum have developed a blood test that may potentially facilitate detection of Alzheimer's at an early stage. It is based on an immuno-chemical analysis using an infrared sensor.

15 Mar 2016

New drug shows promise against mesothelioma

A new drug is showing promise as a treatment for mesothelioma - one of the most lethal cancers of all.

15 Mar 2016

Study on kidney cancer can help pave way toward more effective personalized medicine

Understanding the complexity of cancer is a major goal of the scientific community, and for kidney cancer researchers this goal just got closer. Dr. Chad Creighton, associate professor of medicine and member of the Dan L Duncan Comprehensive Cancer Center Division of Biostatistics at Baylor College of Medicine, led the study that analyzed close to 900 kidney cancers at the molecular level.

15 Mar 2016

Humanoid robot can be used as a tool in therapy for improvement of children with autism

Children with autism have special difficulty in expressing emotions, usually have no social skills and face major problems when communicating. In order to help children with this problem learn to recognize facial expressions in themselves and in others, a group of researchers at the Tec de Monterrey, in Mexico, created a robot using artificial intelligence.

15 Mar 2016

Heart failure drug has unexpected ability to block herpesvirus infection

Today, there is only one class of antiviral medicines against herpesviruses - a family of viruses that cause mononucleosis, herpes, and shingles, among other illnesses - meaning options for treating these infections are limited. If viruses become resistant to these frontline treatments, a growing problem particularly in clinical settings, there are no alternative drugs to serve as backup.

15 Mar 2016

Researchers identify new mutation responsible for spinocerebellar ataxia

Using the genetic information of two different families with three generations of disease, researchers have identified a new mutation responsible for a degenerative and ultimately fatal movement disorder. Through induced pluripotent stem cell techniques, researchers also grew neurons from one patient in the laboratory to be used in future experiments.

15 Mar 2016

Fish's retina inspired autofocus contact lens could benefit presbyopia patients

Making the most of the low light in the muddy rivers where it swims, the elephant nose fish survives by being able to spot predators amongst the muck with a uniquely shaped retina, the part of the eye that captures light. In a new study, researchers looked to the fish's retinal structure to inform the design of a contact lens that can adjust its focus.

15 Mar 2016

Exercise programme reduces symptoms among young adults with first-episode psychosis

An exercise programme devised by researchers at the University of Manchester has dramatically reduced symptoms among young people with first-episode psychosis.

15 Mar 2016

Excessive fat accumulation in lower extremities of children linked to insulin resistance, metabolic disorders

Children with a severe type of spina bifida called myelomeningocele have a high prevalence of obesity and excess fat accumulation in their lower extremities. In a study designed to assess bone, muscle and fat tissue distribution in the lower legs of children with this disease, researchers at Children's Hospital Los Angeles determined that this excess fat tissue is within the muscle boundary (muscle-associated) rather than subcutaneous.

15 Mar 2016

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

The ability to reprogram cells has revolutionized stem cell research with major implications for almost all fields of modern biology. A decade ago Shinya Yamanaka described a procedure that revolutionized stem cell biology. Using a genetic trick that introduces a cocktail of four genes into cultured cells from human biopsies, he was able to generate induced pluripotent stem cells (iPS) from mature skin or blood cells

15 Mar 2016

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Researchers on Mayo Clinic's Florida campus have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent.

15 Mar 2016

Alcohol consumption may increase risk for breast cancer

A University of Houston researcher and his team have discovered an important link between alcohol and breast cancer by identifying a cancer-causing gene triggered by alcohol

15 Mar 2016

Researchers discover potentially-pathogenic bacteria in water supply pipes

The human microbiome, a diverse collection of microorganisms living inside us and on our skin, has attracted considerable attention for its role in a broad range of human health issues. Now, researchers are discovering that the built environment also has a microbiome, which includes a community of potentially-pathogenic bacteria living inside water supply pipes.

15 Mar 2016

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

New research from Boston Children's Hospital could potentially change how doctors approach two blinding diseases: 'Wet' age-related macular degeneration (AMD), the leading cause of blindness in the elderly, and macular telangiectasia (MacTel).

15 Mar 2016

New chemical probe could tag cells for detection by MRI

The need to non-invasively "see" and track cells in living persons is indisputable - a boon to both research and development of future therapies. Emerging treatments using stem cells and immune cells are poised to most benefit from cell tracking, which would visualize their behavior in the body after delivery. Clinicians require such data to speed these cell treatments to patients.

15 Mar 2016

One-fourth of seniors acquire new superbugs during hospital stay

One in four seniors is bringing along stowaways from the hospital to their next stop: superbugs on their hands.Moreover, seniors who go to a nursing home or other post-acute care facility will continue to acquire new superbugs during their stay, according to findings made by University of Michigan researchers published today in a JAMA Internal Medicine research letter.

15 Mar 2016

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Researchers report photoimmunotherapy to be effective against elusive gastric cancer cells following transduction with the gene that expresses the extracellular domain protein of HER2. The results are published in the journal Small Molecule Therapeutics in February 2016.

15 Mar 2016

Medical Research News

St. Jude scientists develop insights to guide development of powerful novel anti-influenza drugs

UCSF study marks important step toward finding cure for Ebola

Prognostic test could help lower cancer recurrence for colorectal patients

New blood test may potentially facilitate detection of Alzheimer's disease at early stage

New drug shows promise against mesothelioma

Study on kidney cancer can help pave way toward more effective personalized medicine

Humanoid robot can be used as a tool in therapy for improvement of children with autism

Heart failure drug has unexpected ability to block herpesvirus infection

Researchers identify new mutation responsible for spinocerebellar ataxia

Fish's retina inspired autofocus contact lens could benefit presbyopia patients

Exercise programme reduces symptoms among young adults with first-episode psychosis

Excessive fat accumulation in lower extremities of children linked to insulin resistance, metabolic disorders

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Alcohol consumption may increase risk for breast cancer

Researchers discover potentially-pathogenic bacteria in water supply pipes

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

New chemical probe could tag cells for detection by MRI

One-fourth of seniors acquire new superbugs during hospital stay

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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