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Children with allergic disease have higher risk of heart disease

Children with allergic disease, particularly asthma and hay fever, have about twice the rate of high blood pressure and high cholesterol, setting them on a course for heart disease at a surprisingly early age, reports a new Northwestern Medicine study.

8 Dec 2015

New algorithm helps analyze microscope images of cells growing in petri dishes

Scientists looking for ways to stimulate the growth of neurons can spend hours painstakingly analyzing microscope images of cells growing in petri dishes. A new algorithm developed by Brown University researchers automates that process and analyzes images more accurately than previous automated approaches.

8 Dec 2015

New way to antagonize human nuclear receptor

On Monday 7 December the journal Nature Communications published the research findings of Eindhoven University of Technology (TU/e), Merck Research Laboratories (Merck is known as MSD outside the US and Canada) and Leiden University concerning an entirely new way of antagonizing a human nuclear receptor.

8 Dec 2015

UB researchers develop a way to ramp up conversion of skin cells into dopamine neurons

For decades, the elusive holy grail in Parkinson's disease research has been finding a way to repair faulty dopamine neurons and put them back into patients, where they will start producing dopamine again. Researchers have used fetal material, which is difficult to obtain and of variable quality. Embryonic stem cells represented a tremendous innovation, but making dopamine neurons from stem cells is a long process with a low yield.

8 Dec 2015

Diet linked to development of prostate cancer

New research suggests that what you eat is linked to the development of prostate cancer. Prostate cancer, also known as the "silent killer," is the second leading cause of cancer death in men in the United States, behind lung cancer. It is also the most common type of cancer in men other than skin cancer.

8 Dec 2015

Researchers find new significant link between NPM protein and development of AML

A team of researchers from the National University of Singapore has found a new significant correlation between the protein nucleophosmin (NPM) and the development of an aggressive form of blood cancer called acute myeloid leukemia (AML).

8 Dec 2015

Simple approach to predict viral evolution may improve vaccine efficacy

New results from a study performed at the University of Helsinki suggest that genomic information from circulating influenza viruses can help in producing more efficient seasonal vaccines. The researchers were able to develop a simple approach for reliable real-time tracking and prediction of viral evolution based on whole-genome sequences of influenza viruses.

8 Dec 2015

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Scientists have shown for the first time why loss of the enzyme CD73 in human cancer promotes tumor progression.

8 Dec 2015

Most U.S. hospitals did not adopt effective interventions to address crowding in emergency departments

The most crowded emergency departments in the U.S. have not adopted proven interventions to address crowding, a major public health concern.

8 Dec 2015

People exiting prison or jail get access to health services

With the expansion of Medicaid under the Affordable Care Act, an entire new population is eligible for government health care: low-income men.

8 Dec 2015

Coordinated health care not helping people with mental health conditions

People who are diagnosed with mental health conditions did not see improvements in coordination and quality of care as hoped but did not experience large cuts in access as some had feared under an early alternative payment model designed to encourage coordinated health care, according to a team led by researchers from Harvard Medical School and Johns Hopkins Bloomberg School of Public Health.

8 Dec 2015

Androgen deprivation therapy for prostate cancer may up Alzheimer's disease risk

Men taking androgen deprivation therapy (ADT) for prostate cancer were almost twice as likely to be diagnosed with Alzheimer's disease in the years that followed than those who didn't undergo the therapy, an analysis of medical records from two large hospital systems by Penn Medicine and Stanford University researchers has shown.

8 Dec 2015

Web-based survey system for symptom collection benefits cancer patients

Systematic collection of cancer patients' symptoms using computer surveys was linked to less frequent emergency room admissions, longer average chemotherapy adherence, greater quality of life improvements, and improved survival, according to a new randomized, controlled trial spearheaded by a UNC Lineberger Comprehensive Cancer Center researcher.

8 Dec 2015

Existing compound offers hope for slowing Huntington's disease progression

Currently, there is no treatment to halt the progression of Huntington's disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities. Now, researchers at University of California, San Diego School of Medicine have discovered that an existing compound, previously tested for diabetes, offers hope for slowing HD and its symptoms.

8 Dec 2015

Plasmacytoid dendritic cells may not contribute to late-stage lupus

For years, biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in lupus patients, but until now they haven't known for sure one way or the other.

8 Dec 2015

CTTV launches new web platform for identifying therapeutic targets

The Centre for Therapeutic Target Validation (CTTV) has launched a new web platform for life-science researchers that helps them identify therapeutic targets for new and repurposed medicines. Today's launch underscores the CTTV's commitment to share its data openly to benefit the broader scientific community.

8 Dec 2015

Penile prostheses benefit men with erectile dysfunction

Most men who receive penile prostheses are very satisfied with the implants, indicating that the intervention is a valid treatment for erectile dysfunction.

8 Dec 2015

Macrophages play key role in maintaining healthy arteries after inflammation

Researchers from the University of Toronto have found that a specific cell type plays a key role in maintaining healthy arteries after inflammation. It's a discovery that could provide treatment options for cardiovascular disease -- one of the leading causes of death in Canada.

8 Dec 2015

NEK7 enzyme acts as on-off switch in innate immune system

UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection.

8 Dec 2015

Young men with HIV engage in risky sexual behavior

Young men who have sex with men and have detectable levels of HIV were more likely to report not using a condom during anal intercourse with a partner not infected with HIV, compared with virologically suppressed young men who have sex with men, according to researchers at Columbia University's Mailman School of Public Health.

8 Dec 2015