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Study sheds light on development of ILCs that play vital role in body's immune defense

Through the use of powerful genomic techniques, researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases have found that the development of immune cells, called innate lymphoid cells (ILCs), gradually prepares these cells for rapid response to infection. This work, which appeared online today in Cell, sheds light on the development and function of a cell type that is increasingly recognized as having an important role in the body's immune defense. NIAMS is part of the National Institutes of Health.

6 May 2016

Globin gene transfer to treat beta-thalassemias shows promise in first clinical trial

Promising results from the first clinical trials of globin gene transfer to treat beta-thalassemias-inherited forms of anemia-have eliminated the need for blood transfusions in some individuals.

6 May 2016

Study identifies sex differences in statin therapy among coronary artery disease patients

Statins are equally effective at decreasing risk of coronary events in men and women, and yet women are less likely to be prescribed these cholesterol-lowering drugs than men.

6 May 2016

Mixed picture for diabetes mortality trends

A large registry analysis shows that younger people may be missing out on a general decline in mortality rates among patients with diabetes.

6 May 2016

Pulmonary hypertension impacts walking ability in SSc patients

The results of a meta-analysis show the adverse impact pulmonary hypertension has on the walking stamina of patients with systemic sclerosis.

6 May 2016

More evidence for combination therapy benefits in PAH

Another meta-analysis adds to evidence of increased benefits for patients with pulmonary arterial hypertension who are given combination therapy.

6 May 2016

Teledermatology improves patients' access to dermatologists

Teledermatology significantly improved access to specialized skin care for a group of patients that traditionally has limited options, according to an independent study led by researchers at the RAND Corporation and Harvard Medical School's Department of Health. The findings appear in a JAMA Dermatology article published online May 4.

6 May 2016

Short sleep duration along with frequent snoring may influence breast cancer survival

A new study reports that short sleep duration combined with frequent snoring reported prior to cancer diagnosis may influence subsequent breast cancer survival.

6 May 2016

Bim protein may hold clue for immunotherapy response in metastatic melanoma patients

A protein called Bim may hold the clue to which patients may be successful on immunotherapy for metastatic melanoma, according to the results of a study by Mayo Clinic researchers led by senior author Haidong Dong, M.D., Ph.D., and published online in the May 5 edition of JCI Insight.

6 May 2016

Scientists use non-invasive way to track rapid myelination of nerve fibers in children's brains

Much like electricity traveling down wires, nerve impulses in our brain travel along nerve fibers. And just as wires need insulation to function well, nerve fibers, too, rely on a kind of insulation called myelin, a fatty substance that protects them and increases the speed at which nerve impulses travel.

6 May 2016

Cancerous lung tumors can alter metabolism by hijacking circadian mechanisms

University of California, Irvine scientists who study how circadian rhythms - our own body clocks - control liver function have discovered that cancerous lung tumors can hijack this process and profoundly alter metabolism.

6 May 2016

Patient-oriented online health resources can impact clinical outcomes of pancreatic cancer patients

The Internet has become a powerful and important resource for daily life. When patients receive a medical diagnosis, particularly a difficult one like pancreatic cancer, the web can be an essential information tool, helping to enable patients to have meaningful discussions with health care providers. However, new research from Beth Israel Deaconess Medical Center published today in JAMA Surgery suggests that online information about pancreatic cancer is often written at a prohibitively high reading level and lacks accuracy concerning alternative therapies.

6 May 2016

Doctor’s access to vaccination data can improve pediatric immunization coverage

Exchange of immunization data between a centralized city immunization registry and provider electronic health records led to significant improvements in pediatric immunization coverage, a reduction in over-immunization for adolescents, and increased completeness of immunization records, according to a study conducted at Columbia University's Mailman School of Public Health, Columbia University Medical Center, NewYork-Presbyterian, and the New York City Department of Health and Mental Hygiene's Citywide Immunization Registry.

6 May 2016

Female sex hormone estradiol may protect women against sexually transmitted viral infections

A team of researchers led by McMaster University's Charu Kaushic has revealed for the first time how estradiol, a female sex hormone present during the menstrual cycle and found in oral contraceptives, may work to protect women against sexually transmitted viral infections.

6 May 2016

Drinking tart Montmorency cherry juice can reduce early signs of hypertension

Drinking tart Montmorency cherry juice significantly reduces high blood pressure at a level comparable to that achieved by medication, according to new research from Northumbria University, Newcastle.

6 May 2016

Studies show mango consumption may contribute to protective health effects

Four new studies surrounding the effects of mango consumption suggest this superfruit has the potential to help combat adverse effects associated with high fat diets and obesity (animal study), as well inhibit growth of fat cells (anti-lipogenic properties in an in-vivo study), slow advancement of breast cancer tumors (animal study), as well as improve regularity and decrease inflammation associated with constipation (human subject study).

6 May 2016

Development of atherosclerosis can increase osteoporosis risk

Patients with atherosclerosis—the buildup of cholesterol and fat in arteries—are at a higher risk of osteoporosis. A new study published in the American Journal of Physiology—Endocrinology and Metabolism shows how the development of atherosclerosis encourages the loss of bone density.

6 May 2016

Gene-replacement therapy could be potential treatment option for SMARD1

Spinal muscular atrophy (SMA) is a disease that causes progressive degeneration in the nerve cells that control muscles, thereby causing muscle weakness and eventually death.

6 May 2016

Memory study shows how people can intentionally forget past experiences

Context plays a big role in our memories, both good and bad. Bruce Springsteen's "Born to Run" on the car radio, for example, may remind you of your first love -- or your first speeding ticket. But a Dartmouth- and Princeton-led brain scanning study shows that people can intentionally forget past experiences by changing how they think about the context of those memories.

6 May 2016

Depressed moms not physiologically 'in sync' with their children

Mothers with a history of depression are not physiologically "in sync" with their kids, according to a new study from Binghamton University. While researchers have known for a while that depression is associated with interpersonal problems with others, this is the first study to examine whether this is also evident physiologically.

6 May 2016

Medical Research News

Study sheds light on development of ILCs that play vital role in body's immune defense

Globin gene transfer to treat beta-thalassemias shows promise in first clinical trial

Study identifies sex differences in statin therapy among coronary artery disease patients

Mixed picture for diabetes mortality trends

Pulmonary hypertension impacts walking ability in SSc patients

More evidence for combination therapy benefits in PAH

Teledermatology improves patients' access to dermatologists

Short sleep duration along with frequent snoring may influence breast cancer survival

Bim protein may hold clue for immunotherapy response in metastatic melanoma patients

Scientists use non-invasive way to track rapid myelination of nerve fibers in children's brains

Cancerous lung tumors can alter metabolism by hijacking circadian mechanisms

Patient-oriented online health resources can impact clinical outcomes of pancreatic cancer patients

Doctor’s access to vaccination data can improve pediatric immunization coverage

Female sex hormone estradiol may protect women against sexually transmitted viral infections

Drinking tart Montmorency cherry juice can reduce early signs of hypertension

Studies show mango consumption may contribute to protective health effects

Development of atherosclerosis can increase osteoporosis risk

Gene-replacement therapy could be potential treatment option for SMARD1

Memory study shows how people can intentionally forget past experiences

Depressed moms not physiologically 'in sync' with their children

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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