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Caltech researchers map out pathways of neurons responsible for Parkinson's motor impairments

Because billions of neurons are packed into our brain, the neuronal circuits that are responsible for controlling our behaviors are by necessity highly intermingled. This tangled web makes it complicated for scientists to determine exactly which circuits do what. Now, using two laboratory techniques pioneered in part at Caltech, Caltech researchers have mapped out the pathways of a set of neurons responsible for the kinds of motor impairments--such as difficulty walking--found in patients with Parkinson's disease.

21 Apr 2016

Gladstone scientists bioengineer micro-scale heart tissues from stem cells

Scientists at the Gladstone Institutes have invented a new way to create three-dimensional human heart tissue from stem cells. The tissue can be used to model disease and test drugs, and it opens the door for a precision medicine approach to treating heart disease. Although there are existing techniques to make three-dimensional tissues from heart cells, the new method dramatically reduces the number of cells needed, making it an easier, cheaper, and more efficient system.

21 Apr 2016

Utah researchers link military sexual trauma to higher risk for veteran homelessness

The devastating consequences of sexual trauma in the military reported by 25 percent of female and 1 percent of male veterans who served in the U.S. armed forces don't end with psychological and physical trauma, but are associated with a much higher risk for homelessness, a study led by Utah researchers has found.

21 Apr 2016

Multivitamin use prior to diagnosis may reduce effects of CIPN in breast cancer survivors

Researchers at Roswell Park Cancer Institute, in collaboration with investigators from the cooperative group SWOG, have found that use of multivitamins prior to diagnosis may reduce the risk of neuropathy in breast cancer patients treated with the class of drugs known as taxanes. The team will present their findings at the American Association for Cancer Research Annual Meeting 2016, to be held April 16-20 in New Orleans.

21 Apr 2016

Novel method could help analyze GWAS results for sporadic diseases

Using a novel method, Whitehead Institute researchers have determined how a non-coding mutation identified in genome-wide association studies can contribute to sporadic Parkinson's disease (PD). The approach could be used to analyze GWAS results for other sporadic diseases with genetic causes, such as multiple sclerosis, diabetes, and cancer.

21 Apr 2016

Low levels of 25-hydroxyvitamin D highly prevalent among children with type 1 diabetes

During the past two decades, vitamin D status, defined as serum concentration of 25-hydroxyvitamin D, has emerged as a predictor of key clinical outcomes including bone health, glucose metabolism, cardiovascular health, immune health and survival.

21 Apr 2016

Hot packs or hot-water immersion may be effective in treating jellyfish stings

A recent study by researchers at the University of Hawaiʻi at Mānoa, published this month in the journal Toxins, may finally put to rest the ongoing debate about whether to use cold or heat to treat jellyfish stings. Their systematic and critical review provides overwhelming evidence that clinical outcomes from all kinds of jellyfish stings are improved following treatment with hot packs or hot-water immersion.

21 Apr 2016

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer's disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.

21 Apr 2016

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children's Research Hospital and at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine.

21 Apr 2016

Climate change, global travel may increase dengue epidemic risk

Researchers at Umea University have developed a model for evidence-based predictions of the mosquito-borne dengue virus. Results show that global travel and climate change increase the risk for epidemics of dengue, and potentially other climate-sensitive infectious diseases carried by mosquitos, spreading into temperate areas. This according to a doctoral dissertation at Umeå University.

21 Apr 2016

MAILES study finds link between fatty diets and sleep

University of Adelaide researchers have found that men who consume diets high in fat are more likely to feel sleepy during the day, to report sleep problems at night, and are also more likely to suffer from sleep apnea.

21 Apr 2016

Non-invasive test to diagnose EoE could replace need for repeated endoscopy

A non-invasive test to diagnose and monitor an inflammatory disease that injures the esophagus - called eosinophilic esophagitis or EoE - would replace the need for repeated endoscopy for a growing number of children and adults with this relatively new condition.

21 Apr 2016

Scientists aim to identify marker that could indicate aggressive basal cell skin cancer

Most basal cell skin cancers are easily removed -- those on the arm, leg or back. But when the cancer is on the eyelid or when it starts to invade surrounding tissue, it's no longer straightforward.

21 Apr 2016

Study explores effectiveness of cognitive behavioral therapy in primary care for depressed teenagers

Depressed teenagers who received cognitive behavioral therapy in their primary care clinic recovered faster, and were also more likely to recover, than teens who did not receive the primary care-based counseling, according to a Kaiser Permanente study published today in the journal Pediatrics.

21 Apr 2016

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

In our bioanalytical mass spectrometry lab we use proteomics techniques to try to understand more about Alzheimer's disease. The primary thrust of our research is that we're interested in understanding the changes that take place outside of the brain and how those correlate with what's taking place inside the brain

From Pittcon 21 Apr 2016

Scientists identify genetic variants that may influence wellbeing, depression and neuroticism

An international group of more than 190 scientists who analyzed the genomes of 298,420 individuals have found genetic variants that may influence our sense of wellbeing, depression and neuroticism.

21 Apr 2016

Single dose of intraoperative radiotherapy effective for early stage breast cancer patients

In the South East of England, a patient experience study of 18 early stage breast cancer patients who opted for single dose intraoperative radiotherapy, found positive patient reported outcomes for this alternative to standard daily external beam radiotherapy.

21 Apr 2016

Patients who survived life-threatening illness in ICU at increased risk for psychiatric symptoms

Results of a multi-institutional national study of nearly 700 people who survived life-threatening illness with a stay in an intensive care unit (ICU) suggest that a substantial majority of them are at high risk for persistent depression, anxiety and post-traumatic stress disorder — especially if they are female, young and unemployed.

21 Apr 2016

New diagnostic approach may help physicians more efficiently screen for dementia

A tiered diagnostic approach that incorporates clinical, imaging and laboratory data may help physicians more efficiently screen for neurodegenerative disorders such as dementia, according to the consensus of a multi-disciplinary panel of experts.

From Quest Diagnostics 21 Apr 2016

Orthocell announces further validation of 'Cell Factory' concept for generation of bone, cartilage

Regenerative medicine company Orthocell Limited is pleased to announce further validation of ‘Cell Factory’ concepts for generating tissue specific growth factors and protein’s to aid in the healing and regeneration of bone, tendon and cartilage.

21 Apr 2016

Medical Research News

Caltech researchers map out pathways of neurons responsible for Parkinson's motor impairments

Gladstone scientists bioengineer micro-scale heart tissues from stem cells

Utah researchers link military sexual trauma to higher risk for veteran homelessness

Multivitamin use prior to diagnosis may reduce effects of CIPN in breast cancer survivors

Novel method could help analyze GWAS results for sporadic diseases

Low levels of 25-hydroxyvitamin D highly prevalent among children with type 1 diabetes

Hot packs or hot-water immersion may be effective in treating jellyfish stings

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Climate change, global travel may increase dengue epidemic risk

MAILES study finds link between fatty diets and sleep

Non-invasive test to diagnose EoE could replace need for repeated endoscopy

Scientists aim to identify marker that could indicate aggressive basal cell skin cancer

Study explores effectiveness of cognitive behavioral therapy in primary care for depressed teenagers

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

Scientists identify genetic variants that may influence wellbeing, depression and neuroticism

Single dose of intraoperative radiotherapy effective for early stage breast cancer patients

Patients who survived life-threatening illness in ICU at increased risk for psychiatric symptoms

New diagnostic approach may help physicians more efficiently screen for dementia

Orthocell announces further validation of 'Cell Factory' concept for generation of bone, cartilage

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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