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Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

Flinders University scientists are looking to bacteriophages – highly specific viruses - as the as the best way to attack antibiotic-resistant bacterial superbug infections.

21 Apr 2016

LAP defects may lead to lupus-like autoimmune disorder

A casual observation about size differences in mice has led to the discovery that defects in a process for digesting dead cells called LC3-associated phagocytosis (LAP) may lead to a lupus-like autoimmune disorder. St. Jude Children's Research Hospital scientists led the research, which appears as an advance online publication today in the scientific journal Nature.

21 Apr 2016

High fructose consumption during pregnancy may increase risk factors for heart disease in children

The negative health effects of consuming large amounts of fructose could impact several generations, according to researchers at The University of Texas Medical Branch at Galveston.

21 Apr 2016

Study finds links between phthalate exposure and obesity

Exposure to chemicals found in everyday products could affect the amount of fat stored in the body, according to a study by University of Georgia researchers.

21 Apr 2016

Non-invasive optogenetic therapy can help treat chronic pain

The potential of light as a non-invasive, highly-focused alternative to pain medication was made more apparent thanks to research conducted by scientists at the Montreal Neurological Institute and Hospital of McGill University and the McGill University Health Centre.

21 Apr 2016

Savouring positive memories can boost mood in individuals with mental health problems

Researchers from the University of Liverpool have published a study highlighting the effectiveness of using positive memories and images to help generate positive emotions.

21 Apr 2016

Mother’s misperception of child's weight status linked to childhood obesity or malnutrition

A new study from the University of Houston Department of Health and Human Performance finds a child's risk for obesity or malnutrition may be tied to the mother's misperception of her child's weight status. A key to understanding this phenomenon may lie in how she regards her own weight status. Researchers say the situation shows that healthcare providers need to broaden their health care screenings.

21 Apr 2016

New study shows visuomotor errors accumulate during memory delay

Who will win the women's singles tennis title at the 2016 Rio Olympics this August? That's a question recent York U brain research can help answer.

21 Apr 2016

Study discusses adequacy of fluid intake for replacing meaningful water losses

A study from the Journal of the American College of Nutrition (JACN) discusses fluid intake adequacy in detail and a simple tool is reviewed that may help healthy, active, low-risk populations answer the question, "Am I drinking enough?" The article "Am I Drinking Enough? Yes, No, and Maybe" by Samuel N. Cheuvront PhD, RD and Robert W. Kenefick PhD is made available with Free Access in JACN Issue 35(2) 2016, the official publication of the American College of Nutrition.

21 Apr 2016

Scientists discover CD2AP protein that plays key role in nervous system

University of Louisville researchers have discovered that a protein previously known for its role in kidney function also plays a significant role in the nervous system. In an article featured in the April 13 issue of the Journal of Neuroscience, they show that the adaptor protein CD2AP is a key player in a type of neural growth known as collateral sprouting.

21 Apr 2016

Athletes who have psychosomatic symptoms prior to concussion may take longer to recover

Athletes may take longer to recover after concussion if they had experienced psychosomatic symptoms before they became concussed, report researchers.

21 Apr 2016

Prompt attention may limit recurrence risk in TIA patients

Centres with procedures in place for the rapid assessment of patients with transient ischaemic attack or minor stroke achieve low recurrence rates in these patients, a multinational study shows.

21 Apr 2016

Imatinib-related symptom burden linked to adherence in Indian CML patients

Research shows low adherence to imatinib in Indian patients with chronic myeloid leukaemia, with an association between nonadherence and worse symptom burden related to treatment.

21 Apr 2016

Frontline nilotinib supported for newly diagnosed CP-CML

Long-term results from the ENESTnd trial indicate a favourable risk-benefit profile for frontline use of nilotinib in patients within 6 months of chronic phase-chronic myeloid leukaemia diagnosis.

21 Apr 2016

KEYNOTE-001 findings add support to pembrolizumab for advanced melanoma

A third of patients with advanced or metastatic melanoma will achieve an objective response to treatment with the programmed cell death protein inhibitor pembrolizumab, suggest KEYNOTE-001 findings, regardless of whether they have previously been treated with ipilimumab.

21 Apr 2016

Pre-TKI cytokine profiling predicts CP-CML outcome

Measuring levels of transforming growth factor-α and interleukin-6 may help identify patients with newly diagnosed chronic phase-chronic myeloid leukaemia at risk of a poor outcome from tyrosine kinase inhibitor therapy, research suggests.

20 Apr 2016

Additional chromosomal abnormalities prognostic for CML

Additional chromosomal abnormalities can be used to create two prognostic groups of patients with chronic myeloid leukaemia, suggests research published in Blood.

20 Apr 2016

Proteins can be used as targets to deliver drugs into stressed cancer cells

Targeted missiles that can enter cancer cells and deliver lethal cell toxins without harming surrounding healthy tissue. This has been a long-standing vision in cancer research, but it has proved difficult to accomplish. A research group at Lund University in Sweden has now taken some crucial steps in this direction.

20 Apr 2016

Researchers discover new, previously underappreciated role for immature dentate gyrus granule cells

University of Alabama at Birmingham researchers have proposed a model that resolves a seeming paradox in one of the most intriguing areas of the brain -- the dentate gyrus.

20 Apr 2016

Researchers develop insoles impregnated with silver nanoparticles to treat diabetic foot syndrome

Scientists from Tomsk Polytechnic University and National Autonomous Mexico University develop techniques to treat diabetic foot syndrome with special insoles with silver nano-particles. The techniques help to fight ulcers appearing on feet in diabetic patients, facilitates their healing and disinfection, reducing the risk of amputation.

20 Apr 2016