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Death risk is higher for dementia patients who take antipsychotic drugs, new study shows

Drugs aimed at quelling the behavior problems of dementia patients may also hasten their deaths more than previously realized, a new study finds.

19 Mar 2015

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified what they describe as "the long-sought culprit" in the mystery behind a cell-signaling breakdown that triggers heart failure. The condition, which affects nearly 6 million Americans and 23 million people worldwide, is marked by progressive weakening and stiffening of the heart muscle and the organ's gradual loss of blood-pumping ability.

19 Mar 2015

New approach to improve cardiac regeneration

The heart tissue of mammals has limited capacity to regenerate after an injury such as a heart attack, in part due to the inability to reactivate a cardiac muscle cell and proliferation program. Recent studies have indicated a low level of cardiac muscle cell (cardiomyocytes) proliferation in adult mammals, but it is insufficient to repair damaged hearts.

19 Mar 2015

Cardiovascular researchers identify MG53 protein necessary for repairing injured kidney cells

Cardiovascular researchers at The Ohio State University Wexner Medical Center have shown that a protein known as MG53 is not only present in kidney cells, but necessary for the organ to repair itself after acute injury. Results from this animal model study are published in the journal Science Translational Medicine.

19 Mar 2015

IU researchers reveal how Toxoplasma parasites modify brain cells

Rodents infected with a common parasite lose their fear of cats, resulting in easy meals for the felines. Now IU School of Medicine researchers have identified a new way the parasite may modify brain cells, possibly helping explain changes in the behavior of mice -- and humans.

19 Mar 2015

New scoring system may help predict memory and thinking problems in elderly people

Researchers have developed a new scoring system to help determine which elderly people may be at a higher risk of developing the memory and thinking problems that can lead to dementia, according to a new study published in the March 18, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Mar 2015

MSU researchers discover what causes death in children with cerebral malaria

Malaria kills a child every minute. While medical researchers have successfully developed effective drugs to kill the malaria parasite, efforts to treat the effects of the disease have not been as successful. But that soon may change.

19 Mar 2015

Study reveals conclusive results in reducing toxicities for Asian patients with mRCC

A study led by the Genitourinary (GU) oncology team at National Cancer Centre Singapore has revealed conclusive results in reducing toxicities for Asian patients with metastatic renal cell carcinoma (mRCC) or cancer that has spread beyond the kidney.

19 Mar 2015

Spironolactone drug reduces side effects of corticosteroid-based dermatological creams

Basic research on blood pressure has led researchers from Inserm (Inserm Unit 1138, "Cordeliers Research Centre") to obtain unexpected results: drugs used to treat hypertension (high blood pressure) reduce side effects from corticosteroid-based creams used to treat certain skin diseases.

19 Mar 2015

Study examines cancer survival statistics for Indigenous Australians

Cancer Council Queensland is calling for enhanced joint efforts to improve Indigenous cancer control this Close the Gap day (tomorrow, Thursday 19 March), following the release of research findings that cancer survival is lower for Indigenous than non-Indigenous Australians for all cancers combined, and for many specific types of cancer.

19 Mar 2015

New tool assesses performance of everyday activities in people with TBI

A recent article by Kessler Foundation researchers describes Actual Reality; as a new tool for assessing performance of activities of everyday life (ADL) in people with traumatic brain injury (TBI). The article, "Actual Reality: Using the Internet to assess everyday functioning after traumatic brain injury," was epublished on February 19 in Brain Injury.

19 Mar 2015

People with severe schizophrenia have major differences in brain networks

People with a severe form of schizophrenia have major differences in their brain networks compared to others with schizophrenia, bipolar disorder and healthy individuals, a new study from the Centre for Addiction and Mental Health shows.

19 Mar 2015

New bodily process may explain low blood oxygen levels for cystic fibrosis patients with lung infection

Researchers have defined a new bodily process in mice that may explain why blood oxygen levels are lower for patients with cystic fibrosis when they get a lung infection.

19 Mar 2015

New approach to improve IVF treatment

Women who have difficulty getting pregnant often turn to in-vitro fertilization (IVF), but it doesn't always work. Now scientists are taking a new approach to improve the technique by studying the proteins that could help ready a uterus for an embryo to implant in its wall.

19 Mar 2015

Researchers discover new cause to explain development of temporal lobe epilepsy

Epilepsy is a very prevalent neurological disorder. Approximately one-third of patients are resistant to currently available therapies. A team of researchers under the guidance of the Institute of Cellular Neurosciences at the University of Bonn has discovered a new cause to explain the development of temporal lobe epilepsy: At an early stage, astrocytes are uncoupled from each other.

19 Mar 2015

Early repeat scan rate for lung cancer decreases by more than 80% with second LDCT screens

The German Lung Cancer Screening Intervention Trial shows that the early repeat scan rate for suspicious findings decreased by more than 80% with the second and subsequent low-dose computed tomography (LDCT) screens, but emphasizes the need to have an organized screening program with the baseline scan available for comparison.

19 Mar 2015

Rural community in Brazil still follows sleep/wake times similar to pre-industrial times

A new study, published today in the journal Scientific Reports, has identified a rural community in Brazil that still follows the earlier sleep and wake times similar to pre-industrial times.

19 Mar 2015

RUB biochemists gain new insights into generation, maintenance of circadian rhythms

Biochemists at the Ruhr-Universität Bochum have gained new insights into the generation and maintenance of circadian rhythms. They demonstrated that the Ras protein is important for setting the phase of such a circadian clock, as its activity determines the period length of the rhythm.

19 Mar 2015

Transplanted regulatory T cells may help in controlling inflammatory diseases

With a $2 million grant from the National Institutes of Health, a team of researchers - including Rensselaer Polytechnic Institute professor Juergen Hahn - will investigate the potential of using transplanted regulatory T cells (Tregs) to reduce inflammation in diseases like inflammatory bowel disease, which currently has no known viable treatment options.

19 Mar 2015

OSU researchers find link between low levels of vitamin D and depression in young women

A new study from Oregon State University suggests there is a relationship between low levels of vitamin D and depression in otherwise healthy young women.

19 Mar 2015

Medical Research News

Death risk is higher for dementia patients who take antipsychotic drugs, new study shows

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

New approach to improve cardiac regeneration

Cardiovascular researchers identify MG53 protein necessary for repairing injured kidney cells

IU researchers reveal how Toxoplasma parasites modify brain cells

New scoring system may help predict memory and thinking problems in elderly people

MSU researchers discover what causes death in children with cerebral malaria

Study reveals conclusive results in reducing toxicities for Asian patients with mRCC

Spironolactone drug reduces side effects of corticosteroid-based dermatological creams

Study examines cancer survival statistics for Indigenous Australians

New tool assesses performance of everyday activities in people with TBI

People with severe schizophrenia have major differences in brain networks

New bodily process may explain low blood oxygen levels for cystic fibrosis patients with lung infection

New approach to improve IVF treatment

Researchers discover new cause to explain development of temporal lobe epilepsy

Early repeat scan rate for lung cancer decreases by more than 80% with second LDCT screens

Rural community in Brazil still follows sleep/wake times similar to pre-industrial times

RUB biochemists gain new insights into generation, maintenance of circadian rhythms

Transplanted regulatory T cells may help in controlling inflammatory diseases

OSU researchers find link between low levels of vitamin D and depression in young women

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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