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Researchers find mechanism behind pancreatic cancer cells' resistance to certain drugs

Pancreatic cancer is on track to become the second leading cause of cancer-related deaths by 2020. These statistics are due, in part, to pancreatic cancer's resistance to most targeted cancer therapies. Working with pancreatic cancer cells, researchers have now found a mechanism that could be responsible for the cancer's resistance to at least one targeted approach.

19 Apr 2016

Well-established optics technique can locate brain tumors within a minute compared to conventional methods

When operating on cancer, surgeons want to remove tumors and not healthy tissue. This is especially important and challenging when dealing with brain tumors, which are often spread out and mixed in with the healthy tissue. Now, researchers have shown that a well-established optics technique can reveal exactly where brain tumors are, producing images in less than a minute -- unlike conventional methods that can take a whole day.

19 Apr 2016

Removing immunomodulatory protein improves symptoms of muscular dystrophy in mice

Removing an immunomodulatory protein called osteopontin improves the symptoms of mice with muscular dystrophy by changing the type of macrophages acting on damaged muscle tissue, according to a paper published in The Journal of Cell Biology.

19 Apr 2016

Study describes precise mechanisms that enable TB bacteria to persist in the body

Bacteria that cause tuberculosis trick immune cells meant to destroy them into hiding and feeding them instead. This is the result of a study led by researchers from NYU Langone Medical Center and published online April 18 in Nature Immunology.

19 Apr 2016

OASIS study to investigate link between SIDS and alteration on newborn hearing screen test

Seattle Children's is partnering on the launch of a study called the 'Oto-Acoustic Signals in SIDS'study that will investigate a possible association between Sudden Infant Death Syndrome (SIDS) and hearing alteration on the newborn hearing screen test.

19 Apr 2016

SBRT for prostate cancer treatment offers higher cure rate than many traditional approaches

A five-year study shows that Stereotactic Body Radiation Therapy (SBRT) to treat prostate cancer offers a higher cure rate than more traditional approaches, according to researchers at UT Southwestern Medical Center Harold C. Simmons Comprehensive Cancer Center.

19 Apr 2016

Actin filaments may be key to molecular machinery that forms, stores long-term memories

Thank the little "muscles" in your neurons for allowing you to remember where you live, what your friends and family look like and a lot more.

19 Apr 2016

New study links specific psychological, social work factors with sleep problems

A new study found that specific psychological and social work factors were associated with sleep problems both concurrently and two years after exposure, indicating prolonged consequences.

19 Apr 2016

Low doses of bisphenol A can affect development of metabolism, reproductive and nervous systems

If rats are exposed to bisphenol A in low doses during early development it can lead to reduced sperm count, obesity and changes to breast development and behaviour. These are some of the findings of a new study from the National Food Institute, Technical University of Denmark. The results support previous animal studies, which have shown that low doses of bisphenol A can affect development of the metabolism as well as the reproductive and nervous systems.

19 Apr 2016

Cyclodextrin offers potential new therapy for cardiovascular disease

An American mother's hunch might result in new treatments for patients who can't tolerate conventional cholesterol-lowering drugs.

19 Apr 2016

Delay in radiation therapy increases chances of DCIS recurrence in women

Delaying radiation therapy too long after surgery significantly increases the risk of recurrent tumors in women treated for very early, or what is referred to as "stage 0," breast cancer, according to new research at Washington University School of Medicine in St. Louis.

19 Apr 2016

Study points to novel way to treat diabetes in some patients

Blocking the hormone that raises sugar levels in the blood could increase insulin levels while keeping blood sugar levels down.

19 Apr 2016

Newly discovered player in epigenetic regulation closely linked to known cancer promoters

If genes form the body's blueprint, then the layer of epigenetics decides which parts of the plan get built. Unfortunately, many cancers hijack epigenetics to modulate the expression of genes, thus promoting cancer growth and survival.

19 Apr 2016

Researchers examine neuropsychological effect in ecstasy users

Researchers from the University of Liverpool have conducted a study examining the effect ecstasy has on different parts of the brain.

19 Apr 2016

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Asthma is an enormous public health problem that continues to grow larger, in part because scientists don't fully understand how it is caused. Existing therapies don't cure the disease and often don't even significantly alleviate the symptoms. Now, scientists from the Perelman School of Medicine at the University of Pennsylvania and Rutgers University have identified a biological pathway that potentially explains why current asthma therapies don't work well in many cases—and might be targeted to help those patients.

19 Apr 2016

Study shows women may face decreased kidney damage from ischemia reperfusion injury

After a kidney transplant, women may experience decreased kidney damage from ischemia reperfusion injury compared to men due to the impact of gender-specific hormones, suggests a new preclinical study and an analysis of patient data published online in the Journal of Clinical Investigation from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Apr 2016

Penn researchers report results of CAR therapy trial in brain cancer patients

Immune cells engineered to seek out and attack a type of deadly brain cancer known as glioblastoma (GBM) were found to have an acceptable safety profile and successfully migrate to and infiltrate tumors, researchers from Penn Medicine and Harvard University reported at the AACR Annual Meeting 2016.

19 Apr 2016

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Cancer cells often devise ways to survive even in the presence of toxic chemotherapy. Now, a research team led by investigators at Beth Israel Deaconess Medical Center has found a way to attack a process that tumor cells use to escape the effects of standard cancer drugs. The discovery is published online today in the journal Nature Cell Biology.

19 Apr 2016

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia.

19 Apr 2016

Scientists discover new diagnostic marker for liver cancer

Scientists may have discovered a significant new diagnostic marker for liver cancer, according to a paper published in the April 18 online issue of Nature Cell Biology.

19 Apr 2016

Medical Research News

Researchers find mechanism behind pancreatic cancer cells' resistance to certain drugs

Well-established optics technique can locate brain tumors within a minute compared to conventional methods

Removing immunomodulatory protein improves symptoms of muscular dystrophy in mice

Study describes precise mechanisms that enable TB bacteria to persist in the body

OASIS study to investigate link between SIDS and alteration on newborn hearing screen test

SBRT for prostate cancer treatment offers higher cure rate than many traditional approaches

Actin filaments may be key to molecular machinery that forms, stores long-term memories

New study links specific psychological, social work factors with sleep problems

Low doses of bisphenol A can affect development of metabolism, reproductive and nervous systems

Cyclodextrin offers potential new therapy for cardiovascular disease

Delay in radiation therapy increases chances of DCIS recurrence in women

Study points to novel way to treat diabetes in some patients

Newly discovered player in epigenetic regulation closely linked to known cancer promoters

Researchers examine neuropsychological effect in ecstasy users

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Study shows women may face decreased kidney damage from ischemia reperfusion injury

Penn researchers report results of CAR therapy trial in brain cancer patients

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Scientists discover new diagnostic marker for liver cancer

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Leveraging the Radian ASAP in standard casework

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