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Scientists identify role of non-coding elements in shaping human-specific traits

Human-specific variants of four microRNAs may have altered expression levels and gene targets compared to other great apes, according to a study published April 22, 2016 in the open-access journal PLOS ONE by Alicia Gallego from the Institute of Evolutionary Biology, Spain, and colleagues.

10 May 2016

Study shows risk of developing MDD depends on symptom centrality in network

A novel study published in the current issue of Psychotherapy and Psychosomatics discloses how depression may develop.

10 May 2016

Trauma-focused cognitive behavioral therapy effective in overcoming PTSS in children, adolescents

A multicenter randomized controlled trial performed in Germany and published in the current issue of Psychotherapy and Psychosomatics discloses new indications for overcoming trauma in children and adolescents.

10 May 2016

Study highlights role of specific chromosomal deletion in cancer development, progression

In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study of individual genes. Prof. Anna Sablina and her team at VIB/KU Leuven optimized a workflow for the generation of cell lines with targeted chromosomal deletions.

10 May 2016

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates that mindfulness based cognitive therapy (MBCT) is most helpful when antidepressant drugs are not used.

10 May 2016

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

St. Jude Children's Research Hospital scientists report the first evidence that a pathogen-specific antibiotic was less disruptive to the gut microbiome than broad-spectrum antibiotics.

10 May 2016

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

In most cases, tumors of the thymus gland are removed by surgical resection. However, they recur after a few years in up to one third of patients. A research team headed up by thoracic surgeon Bernhard Moser of the Thoracic Surgery Department at MedUni Vienna has successfully demonstrated that these tumors form heat-shock proteins. The lower the concentration of these proteins, the more quickly tumors recur. The study has been published in the leading journal Scientific Reports.

10 May 2016

Novel iPad simulation app can instruct future nurses in monitoring babies and mothers during labor

Sheila Taylor leaned in to see the baby's heartbeat rhythm. She watched as the baby's heartbeat line fell without a corresponding spike showing the mother's uterus contracting down on it.

10 May 2016

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

A new study on the epigenetics of lactose intolerance may provide an approach to understanding schizophrenia and other complex, serious illnesses

10 May 2016

Genetic biomarkers may predict response to psychological treatments in anxious children

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates that genetic biomarkers may predict response to psychotherapy in anxious children.

10 May 2016

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

A recent study reported in the May issue of the Journal of Nuclear Medicine demonstrates that Ga-68 DOTATATE PET/CT scans are superior to In-111 pentetreotide scans, the current imaging standard in the United States for detecting neuroendocrine tumors, and could significantly impact treatment management.

10 May 2016

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Some children and youth with high videogame addiction tendencies may be at risk of sleep deprivation and disorders associated with obesity and poor cardio-metabolic health, Hamilton researchers have found.

10 May 2016

NYUCD awarded $1.6M grant to explore biological and physiological effects of e-cig use on oral health

The National Institute of Dental and Craniofacial Research, a division of the National Institutes of Health, has awarded NYU College of Dentistry Professors Deepak Saxena, MS, PhD, and Xin Li, PhD, a four-year $1.6M NIDCR grant to study the biological and physiological effects of electronic cigarette aerosol mixtures on oral health.

10 May 2016

Transcranial direct current stimulation proves effective for binge-eating disorder

Transcranial direct current stimulation, or tDCS, has proved effective for binge-eating disorder for the first time, according to researchers at the University of Alabama at Birmingham.

10 May 2016

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

The Medical University of South Carolina's Hollings Cancer Center received an $8.9 million grant from the National Cancer Institute designed to foster collaboration across clinical and laboratory research for the study of signaling in sphingolipids, a class of lipids known to be involved in the growth of solid tumor cancers.

10 May 2016

MGH researchers develop device to rapidly diagnose health-care-associated infections

A team of Massachusetts General Hospital investigators has developed a device with the potential of shortening the time required to rapidly diagnose pathogens responsible for health-care-associated infections from a couple of days to a matter of hours.

10 May 2016

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Researchers report in the journal Cancer Cell an experimental therapy that in laboratory tests on human cells and mouse models stops aggressive, treatment-resistant and deadly brain cancers called glioblastoma and high-grade gliomas.

10 May 2016

Smartphones may have potential in treatment of insomnia

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates how the smartphone may have a potential in the treatment of insomnia.

10 May 2016

TSRI scientists design potential drug candidate to treat triple negative breast cancer

In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers—triple negative breast cancer.

10 May 2016

Medical Research News

Scientists identify role of non-coding elements in shaping human-specific traits

Study shows risk of developing MDD depends on symptom centrality in network

Trauma-focused cognitive behavioral therapy effective in overcoming PTSS in children, adolescents

Study highlights role of specific chromosomal deletion in cancer development, progression

lncRNA in placenta may help protect unborn baby from invading pathogens

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

Novel iPad simulation app can instruct future nurses in monitoring babies and mothers during labor

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

Genetic biomarkers may predict response to psychological treatments in anxious children

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

NYUCD awarded $1.6M grant to explore biological and physiological effects of e-cig use on oral health

Transcranial direct current stimulation proves effective for binge-eating disorder

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

MGH researchers develop device to rapidly diagnose health-care-associated infections

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Smartphones may have potential in treatment of insomnia

TSRI scientists design potential drug candidate to treat triple negative breast cancer

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