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TSRI scientists design potential drug candidate to treat triple negative breast cancer

In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers—triple negative breast cancer.

10 May 2016

Caltech researchers discover new potential cause for Crohn's disease

The community of beneficial bacteria that live in our intestines, known as the gut microbiome, are important for the development and function of the immune system. There has been growing evidence that certain probiotics--therapies that introduce beneficial bacteria into the gut--may help alleviate some of the symptoms of intestinal disorders such as Crohn's disease.

10 May 2016

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Neuroimaging studies of interconnected brain networks may provide the "missing links" between behavioral and biological models of cognitive vulnerability to depression, according to a research review in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.

10 May 2016

Study links infant swaddling for sleep with SIDS risk

The risk of Sudden Infant Death Syndrome (SIDS) appears to increase when infants are swaddled while sleeping on their stomachs or sides, new research has found.

10 May 2016

Combination of hormone therapy and radiotherapy halves risk of death from prostate cancer

A longitudinal Nordic study, comparing the results of hormone (antiandrogen) therapy with or without the addition of local radiotherapy, shows that a combination of treatments halves the risk of death from prostate cancer 15 years after diagnosis. This according to a follow-up study recently published in the journal European Urology.

10 May 2016

CoSTREAM project aims to find common mechanisms, pathways in stroke and Alzheimer's disease

Stroke and Alzheimer's disease are major diseases imposing a huge burden on aging societies. It has long been recognized that stroke and Alzheimer's disease often co-occur, and it has been speculated that the two disorders have an overlapping pathogenesis.

10 May 2016

UCLA study shows anti-nausea drug does not increase risk of birth defects

Women suffering from extreme morning sickness often take Zofran (ondansetron) to combat their debilitating nausea and vomiting. However, two studies have found that the drug may increase risk of heart defects and cleft palate in children exposed in utero.

10 May 2016

Study reveals important new findings about rare cancer

A study comprised of 39 international institutions revealed significant new findings about adrenocortical carcinoma (ACC), a rare cancer with an often poor prognosis.

10 May 2016

Study shows women undergoing TAVR have longer-term survival rate compared to men

Data from one of the largest national registries of transcatheter aortic valve replacement (TAVR) patients shows that although women are more likely to experience vascular complications in the hospital, their one-year survival rate is more favorable than men.

10 May 2016

Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Okayama University researchers report that the overexpression of an adhesion molecule found on the surface of fat cells appears to protect mice from developing obesity and diabetes. The findings, published in the journal Diabetes, March 2016, may fuel the development of new therapies targeting these diseases.

9 May 2016

Study shows obese men, women less likely to be employed

A Sheffield Hallam University study has found that obese men and women are less likely to be employed because of their weight.

From Sheffield Hallam University 9 May 2016

Food deprivation may help treat fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung and the Deutsches Krebsforschungszentrum they were able to show that upon deprivation of food a certain protein is produced that adjusts the metabolism in the liver.

9 May 2016

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

The inability to adequately respond to infection can cause a whole-body state of inflammation known as sepsis. This can eventually lead to systemic inflammatory response syndrome (SIRS), and even death.

9 May 2016

Digital media may affect our likelihood of using abstract thought

Tablet and laptop users beware. Using digital platforms such as tablets and laptops for reading may make you more inclined to focus on concrete details rather than interpreting information more abstractly, according to a new study published in the proceedings of ACM CHI '16, the ACM Conference on Human Factors in Computing Systems, to be held May 7-12, 2016.

9 May 2016

Study shows lunar phases do not influence people's behavior

Always surrounded by an aura of mystery, the moon and its possible influence over human behavior has been object of ancestral fascination and mythical speculation for centuries. While the full moon cannot turn people into werewolves, some people do accuse it of causing a bad night's sleep or creating physical and mental alterations. But is there any science behind these myths?

9 May 2016

Survey finds variability among physicians when treating stroke patients

A physician has to make many quick decisions when confronted with a stroke patient. Should treatment be intensive or comfort-based, or somewhere in between?

9 May 2016

Younger women more likely to experience one-year adverse cardiovascular events after PCI

Women younger than 55 years of age who undergo percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) are more likely to experience one-year adverse cardiovascular events due to risk factors such as diabetes and chronic kidney disease, yet they are less likely to receive potent antiplatelet therapy than men. The PROMETHEUS study found that outcomes for both men and women post-PCI are dependent on their baseline risk factors, not their sex.

9 May 2016

Moderate sedation leads to better clinical outcomes than general anesthesia for TAVR patients

A new study finds the use of moderate sedation, in which patients do not need a breathing tube, leads to better clinical outcomes as compared to general anesthesia for patients undergoing transcatheter aortic valve replacement (TAVR).

9 May 2016

Study highlights significance of tiny RNA molecules in tissue regeneration process

Dr. Elizabeth Hutchins, a Post-Doctoral Fellow in TGen's Neurogenomics Division, and co-lead author of the study, said she hopes this investigation eventually enables such things as regenerating cartilage in knees, repairing spinal cords in accident victims, and reproducing the muscles of injured war veterans.

9 May 2016

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Michigan State University researchers used an old-fashioned neurobiology technique to explore new avenues for treatments to reverse a late-onset neurodegenerative disease that robs men of the capacity to walk, run, chew and swallow.

9 May 2016

Medical Research News

TSRI scientists design potential drug candidate to treat triple negative breast cancer

Caltech researchers discover new potential cause for Crohn's disease

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Study links infant swaddling for sleep with SIDS risk

Combination of hormone therapy and radiotherapy halves risk of death from prostate cancer

CoSTREAM project aims to find common mechanisms, pathways in stroke and Alzheimer's disease

UCLA study shows anti-nausea drug does not increase risk of birth defects

Study reveals important new findings about rare cancer

Study shows women undergoing TAVR have longer-term survival rate compared to men

Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Study shows obese men, women less likely to be employed

Food deprivation may help treat fatty liver disease

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

Digital media may affect our likelihood of using abstract thought

Study shows lunar phases do not influence people's behavior

Survey finds variability among physicians when treating stroke patients

Younger women more likely to experience one-year adverse cardiovascular events after PCI

Moderate sedation leads to better clinical outcomes than general anesthesia for TAVR patients

Study highlights significance of tiny RNA molecules in tissue regeneration process

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

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